Comparing heart imaging techniques for coronary artery disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study aims to compare the functional abnormalities detected by myocardial perfusion SPECT imaging with the anatomical findings from coronary computed tomography angiography in patients suspected of having coronary artery disease. The study will enroll 50 patients who will undergo both imaging modalities, including pharmacological stress and rest-phase dynamic and static MPI SPECT, followed by coronary CTA. The goal is to enhance the diagnostic value of MPI SPECT by quantifying myocardial blood flow and calculating myocardial flow reserve, ultimately improving risk assessment for patients with moderate cardiovascular risk.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* suspected coronary artery disease
* referred to coronary CTA or SPECT MPI by the patient's physician
* agrees to the other imaging modality that was not indicated by their physician (coronary CTA or SPECT MPI)
* suitable for informed consent

Exclusion Criteria:

* moderate or severe aortic valve stenosis
* atrial fibrillation
* pregnancy or breastfeeding
* history of coronary artery bypass graft implantation
* history of stent implantation
* chronic renal failure (eGFR \< 30 ml/m2)
* active oncological treatment
* congenital heart disease
* left or right bundle branch block

Where it's running

• Semmelweis University, Medical Imaging Centre
  Budapest, Budapest, Hungary Recruiting

Study contacts

• Principal investigator: Pál Maurovich-Horvat, Prof. Dr. — Semmelweis University Medical Imaging Centre
• Study coordinator: Pál Maurovich-Horvat, Prof. Dr.
• Email: maurovich-horvat.pal@semmelweis.hu
• Phone: +36206632485

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.