Magnetocardiography in people with chest pain and non-obstructive heart arteries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective observational study, researchers test whether magnetocardiography can detect ischemia in patients with chest pain who have non-obstructive arteries on imaging. Eligible participants are adults with ischemic symptoms and mild or no arterial blockage, confirmed by coronary angiography or CT angiography. The test is noninvasive and aims to improve the identification of myocardial ischemia when standard imaging shows little obstruction. Data will be collected to explore the association between magnetocardiography results and ischemic symptoms. The study is conducted at Qilu Hospital of Shandong University in Jinan, China.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older;
* Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing \<70% stenosis at the most severe site or CTA showing non-severe stenosis
* Signed informed consent.

Exclusion Criteria:

* Patients with absolute or relative contraindications to CFR-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy;
* Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease;
* Patients with Hemodynamic instability (systolic blood pressure\<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia,

  #degree atrioventricular block and above that have not returned to normal;
* Patients who have severe renal abnormality with eGFR \<30 ml/min, or patients who are on dialysis;
* Patients with malignant tumors with predicted survival of less than 1 year;
* Pregnant or breastfeeding women;
* Patients who are unable to enter the MCG device, who are unable to perform MCG examination due to interference from metal implants or other reasons, or who are deemed by the investigators to be unsuitable for enrollment.

Where it's running

• Qliu Hospital of Shandong University
  Jinan, Shandong, China Recruiting

Study contacts

• Principal investigator: Yuguo Chen, Professor — Qliu Hospital of Shandong University
• Study coordinator: Jiaojiao Pang, Doctor
• Email: jiaojiaopang@126.com
• Phone: 0086-0531-82165398

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.