AI-assisted cardiac CT to predict coronary artery disease risk

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The ACTION Registry is a prospective, single-centre observational registry at University Hospital Galway that collects multimodal data from adults undergoing clinically indicated cardiac CT. Participants provide consent and give demographic and clinical information, blood samples for cardiovascular and metabolic biomarkers, a resting ECG, and complete lifestyle and risk-factor questionnaires while their standard-of-care cardiac CT is acquired and interpreted. Imaging data, including CT-derived plaque characteristics and a subset with invasive OCT, will be integrated with biochemical and clinical variables for AI-based analyses to stratify cardiovascular risk and explore plaque vulnerability. Data are collected at a baseline visit with routine clinical follow-up information added where available.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥18 years
* Undergoing clinically indicated cardiac CT
* Able and willing to provide informed consent

Exclusion Criteria:

* History of malignancy
* Abnormal renal function (e.g., eGFR or serum creatinine outside reference range)
* Contraindications to iodinated contrast agents or CT imaging

Where it's running

• Clinical Research Facility
  Galway, Ireland Recruiting

Study contacts

• Principal investigator: Faisal Sharif, MBBS, PhD, FRCPI, FESC, FACC — University of Galway
• Study coordinator: Faisal Sharif
• Email: faisal.sharif@universityofgalway.ie
• Phone: +353 91524222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.