Condition

Malnutrition clinical trials and research

• 39Clinical trials
• 38NIH research projects
• 19Countries

Newest Malnutrition clinical trials

All recruiting trials (39)

• Hospital-based look at infants under 6 months with acute malnutrition

  This study follows hospitalized infants under 6 months with acute malnutrition to see how common it is and how they grow during treatment.

  Recruiting at 16 sites Universitas Indonesia · Denpasar, Bali and 15 other locations · NCT07831343

• Preoperative Immunonutrition for bone and soft tissue sarcoma patients

  This study tests whether a short course of an oral nutrition supplement before surgery can help patients with bone or soft tissue sarcomas recover better after major tumor-related surgery.

  Recruiting St. Anne's University Hospital Brno, Czech Republic · Brno · NCT07609329

• Even protein distribution plus exercise for people awaiting liver transplant

  This trial tests whether spreading daily protein evenly and combining it with a 12-week exercise program improves nutrition, muscle mass, and function in people waiting for a liver transplant compared with uneven protein timing or usual advice.

  Recruiting at 2 sites Agricultural University of Athens · Athens, Attica and 1 other locations · NCT07561138

• Preoperative Oral Nutrition for Frail Elderly Hip Fracture Patients

  This observational study tests whether giving preoperative oral nutrition helps frail elderly patients with femur fractures fare better around surgery.

  Recruiting Duzce University · Düzce · NCT07463352

• Nutritional care for adults with type 2 or drug-induced diabetes who are malnourished or at risk

  This observational study will follow adults with type 2 or drug-induced diabetes who are malnourished or at risk to see if taking a diabetes-specific high-calorie, high-protein oral supplement with soluble fiber helps their nutrition, blood sugar, and quality of life.

  Recruiting at 12 sites Outcomes'10 · Santander, Cantabria and 11 other locations · NCT07252765

• Body composition monitoring for people with IBD starting biologic or JAK inhibitor therapy

  This project will use bioelectrical impedance to track lean mass percentage and phase angle over one year in adults with moderate-to-severe Crohn's disease or ulcerative colitis who are starting biologic or JAK inhibitor treatment.

  Recruiting Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Barcelona · NCT07162701

• Depression and nutrition problems after surgical site infections in orthopedic patients

  This study will see how often adults treated for surgical site infections after orthopedic surgery develop depression or problems like malnutrition.

  Recruiting University Hospital, Bordeaux · Bordeaux · NCT07125196

• Remote nutritional prehabilitation for people with invasive cancer starting treatment

  This study will test whether low- versus high-intensity remote nutrition support helps adults with invasive cancer who are starting systemic treatment stick with their treatment and feel better.

  Recruiting University of Vermont Medical Center · Burlington, Vermont · NCT07072377

• High-protein, plant-dominant diet for people with liver cirrhosis

  This 6-month test compares a high-protein, mostly plant-based diet to a usual low-fat animal-protein diet in adults with decompensated cirrhosis who are awaiting kidney transplant to see which better preserves nutrition and muscle.

  Recruiting at 2 sites Agricultural University of Athens · Athens, Attica and 1 other locations · NCT07028580

• Understanding how nutrition affects older hospitalized patients' recovery and survival

  This study looks at how good nutrition can help older patients in the hospital recover faster and live longer after being treated for serious illnesses.

  Recruiting Bispebjerg Hospital · Copenhagen · NCT06946537

• Understanding pediatric feeding disorders at Amiens University Hospital

  This study looks at children under 18 with feeding problems to see how these issues develop and what might help improve their eating and nutrition.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06928714

• Transplanting washed microbiota with nutritional support for gastroptosis

  This study is testing if a new treatment using washed microbiota along with special nutrition can help adults with gastroptosis and malnutrition feel better.

  Recruiting The Second Hospital of Nanjing Medical University · Nanjing, Jangsu · NCT06837194

• Pancreatic enzyme plus oral supplements for older adults at risk of malnutrition

  This will see if taking pancrelipase with oral nutritional supplements helps hospitalized adults aged 70 and older who are at risk of malnutrition absorb nutrients better.

  Recruiting Kantonsspital Aarau · Aarau · NCT06826105

• Comparing high-protein and standard protein nutrition for critically ill patients at risk for refeeding syndrome

  This study is testing whether giving critically ill patients more protein in their nutrition can help them recover better and avoid serious complications while in the ICU.

  Recruiting Shahid Beheshti University · Tehran · NCT06825377

• Nutritional support for older patients after hospital discharge

  This study is testing if providing better nutrition support to older patients after they leave the hospital can help them recover faster and stay out of the hospital.

  Recruiting Herlev and Gentofte Hospital · Herlev · NCT06706661

• Cognitive effects of stomach or esophagus cancer surgery

  This study will see how often people who have surgery for stomach or esophagus cancer develop postoperative delirium and whether it is linked to preoperative depression, frailty, malnutrition, sarcopenia, or lower quality of life.

  Recruiting Karolinska Institutet · Huddinge · NCT06687291

• How nutrition and body composition relate to outcomes in people with IBD

  This study will see if nutrition and muscle mass affect outcomes in people with Crohn's disease or ulcerative colitis who are starting advanced medicines or having IBD-related surgery.

  Recruiting Barts & The London NHS Trust · London · NCT06550310

• Understanding nutrition care in cancer treatment

  This study looks at how dietitians can help cancer patients improve their nutrition and overall well-being during treatment by using personalized plans and tracking their food intake and muscle health.

  Recruiting Uppsala University · Uppsala · NCT06531174

• Impact of protein intake on muscle mass and quality of life during and after radiotherapy

  This study looks at how eating enough protein can help cancer patients keep their muscle mass and improve their quality of life during and after radiotherapy.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT06480266

• Using washed microbiota transplantation to treat malnutrition

  This study is testing if a new treatment using washed gut bacteria can help adults with malnutrition gain weight and improve their health.

  Recruiting The Second Hospital of Nanjing Medical University · Nanjing, Jiangsu · NCT06447220

• Assessing muscle mass and strength in patients with cirrhosis

  This study is testing how muscle mass and strength change in people with cirrhosis to see how it affects their daily lives and health.

  Recruiting University Hospital, Antwerp · Edegem, Antwerpen · NCT06345547

• Survey on malnutrition in hospitalized patients at Pitié-Salpêtrière Hospital

  This study is trying to find out how many hospitalized adults at Pitié-Salpêtrière Hospital are dealing with malnutrition by using a questionnaire and focus groups to gather information.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris, France · NCT06317402

• Evaluating the safety of Omegaven in children with liver disease from parenteral nutrition

  This study is testing whether Omegaven, a fish oil treatment, is safe for children with liver disease caused by long-term feeding through an IV.

  Recruiting at 10 sites Fresenius Kabi · Fountain Valley, California and 9 other locations · NCT06274788

• Improving malnutrition assessment methods

  This study is testing different ways to check for malnutrition in patients to see which methods work best at identifying it and predicting health outcomes over a year.

  Recruiting University of Tartu · Tartu, Tartu · NCT06164925

• Analyzing breath to understand malnutrition

  This study is testing if certain breath markers can help us understand malnutrition in people by looking at how they change with different diets.

  Recruiting Pennington Biomedical Research Center · Baton Rouge, Louisiana · NCT06115148

• Evaluating the safety of SMOFlipid in preventing malnutrition-related complications

  This study is testing if SMOFlipid, a special fat mixture, can help both kids and adults who need long-term feeding through a vein avoid serious nutrition-related problems.

  Recruiting at 4 sites Phase 4 Fresenius Kabi · Atlanta, Georgia and 5 other locations · NCT06049680

• Improving health before colorectal cancer surgery for older patients with malnutrition

  This study is testing whether older patients with colorectal cancer who are malnourished can do better before surgery by focusing on nutrition alone or nutrition plus exercise.

  Recruiting McGill University · Montreal, Quebec · NCT05999370

• Optimized nutritional therapy with early physiotherapy for long-stay ICU patients

  This program tests whether better-tailored nutrition combined with early physiotherapy helps adults on ventilators who are expected to stay in the ICU seven days or more leave the hospital with stronger muscles.

  Recruiting University Hospital, Geneva · Geneva, Canton of Geneva · NCT05865314

• Investigating gut health and nutrition in malnourished Bangladeshi women

  This study is testing how gut health affects malnourished women in Bangladesh and whether a special nutrition plan can improve their health during pregnancy.

  Recruiting International Centre for Diarrhoeal Disease Research, Bangladesh · Dhaka, Dhaka Division · NCT05862363

• Assessing nutritional status in gastric cancer patients using bioelectrical impedance analysis

  This study is testing if a special method can help doctors check the nutrition and body health of gastric cancer patients during their treatment to better support their care.

  Recruiting Medical University of Lublin · Lublin · NCT05723718

• Using imaging to predict malnutrition in cervical cancer patients

  This study is testing if special imaging of a muscle in the back can help doctors predict malnutrition in women with early-stage cervical cancer who have had treatment.

  Recruiting Zhejiang Provincial People's Hospital · Hangzhou, Zhejiang · NCT05709769

• Supporting immune and mitochondrial health in older adults with targeted nutrition

  This trial will test whether a personalized supplement containing branched-chain amino acids, micronutrients, and omega-3s helps older adults with malnutrition and sarcopenia improve muscle, immune, and mitochondrial function.

  Recruiting Centre Hospitalier Universitaire Vaudois · Lausanne, Switzerland · NCT05324475

• Preventing pressure ulcers, malnutrition, poor oral health, and falls in older adults receiving municipal health care

  This study is testing a new program to help prevent pressure ulcers, malnutrition, poor oral health, and falls in older adults living in nursing homes by training staff on better care practices.

  Recruiting Malmö University · Malmö · NCT05308862

• Integrated diagnosis and treatment for chronic kidney disease outcomes

  This study is trying to see if a combined approach to diagnosing and treating chronic kidney disease can help patients manage their health better and improve their overall outcomes.

  Recruiting Capital Medical University · Beijing, Beijing Municipality · NCT05242055

• Continued nutritional support after hospital discharge for malnourished patients

  This study is testing if extra nutritional support after leaving the hospital can help malnourished patients recover better and live longer compared to standard home nutrition.

  Recruiting at 10 sites Kantonsspital Aarau · Barcelona and 17 other locations · NCT04926597

• Does crunching sound affect eating pleasure in older adults who are frail or malnourished?

  This study tests whether crunchy textures in cookies can enhance eating enjoyment for adults 65 and older who are frail, malnourished, or toothless.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice · NCT04923087

• Comparing nutritional screening tools for liver cirrhosis patients

  This study is testing two special questionnaires to see which one better helps find malnutrition in people with liver cirrhosis.

  Recruiting Hospital Clinic of Barcelona · Barcelona, Catalonia · NCT04502719

• Nutritional support for patients with Critical Limb Ischemia

  This study tests if giving nutritional supplements to patients with Critical Limb Ischemia before and after surgery can help them recover better and feel stronger.

  Recruiting Early Phase 1 Boston Medical Center · Boston, Massachusetts · NCT03529019

• Survey on nutritional risk and malnutrition in hospitalized patients

  This study looks at how many hospitalized patients are at risk for malnutrition and how it affects their recovery and hospital costs.

  Recruiting at 8 sites Peking Union Medical College · Beijing, Beijing Municipality and 14 other locations · NCT00289380

NIH-funded research (38)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Azithromycin added to standard care for kids with severe malnutrition in Africa

  This project tests whether giving azithromycin as an extra antibiotic to young children with uncomplicated severe acute malnutrition improves weight gain and recovery compared with amoxicillin or placebo.

  NIH research Washington University · Saint Louis, United States · NIH-11625627

• Gut-Liver-Bone clues to growth problems in malnourished children

  A study in malnourished children and a mouse model looks at how the gut, liver, and bone interact to cause growth faltering and tests a bile-acid therapy that could improve growth and reduce inflammation.

  NIH research University of Texas Med Br Galveston · Galveston, United States · NIH-11595691

• Azithromycin adjunct in kids with severe malnutrition in Africa

  A randomized trial will compare azithromycin, amoxicillin, and placebo as adjunctive antibiotics for children with uncomplicated severe acute malnutrition to see which supports better weight gain and recovery.

  NIH research Washington University · Saint Louis, United States · NIH-11578609

• Digital tools to fight adolescent malnutrition in schools (low-resource settings)

  A school-based mobile health approach helps younger adolescents in low-resource areas improve nutrition and health behaviors.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11520385

• How caregiver mental health affects recovery from severe malnutrition in young children

  This project will track caregivers' depression and anxiety while their children get treatment for severe acute malnutrition to learn how caregiver mental health relates to child recovery and relapse.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11514557

• Preventing Growth Problems in Poor Children by Treating Small Intestine Bacteria

  A phase II effort in urban Bangladesh tests a treatment plan to stop growth failure and malnutrition in young children by addressing small intestinal bacterial overgrowth.

  NIH research University of Virginia · Charlottesville, United States · NIH-11478598

• Prioritizing food system changes to reduce adolescent hunger and malnutrition in low-income areas

  A project will work with teens in low-income urban areas of Nairobi, Kenya, to understand how local food systems affect their nutrition and find practical ways to improve access to healthy foods.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11474068

• Prioritizing food systems for healthier adolescent nutrition in low-income settings

  This grant aims to help adolescents in low-income communities eat better by studying how access to food and local systems affect their nutrition.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11474067

• Prioritizing food systems to improve teens’ nutrition in low-income settings

  A project to help hungry and malnourished adolescents in low-income urban areas by studying how food systems affect what teens eat and how to make healthier choices.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11474066

• Integrated nutrition support for mothers and young children in Guatemala

  This project offers food supplements and counseling to pregnant and new mothers and their young children in rural Guatemala to reduce both maternal overweight and child undernutrition.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11466687

• Using monthly malaria prevention visits to help prevent child malnutrition

  This project uses monthly door-to-door malaria medicine deliveries to also provide extra care to young children in the Sahel to try to reduce both malaria and malnutrition.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11465099

• Azithromycin as extra treatment for uncomplicated severe acute malnutrition

  This project compares giving azithromycin, amoxicillin, or a placebo to young children with uncomplicated severe acute malnutrition to see which helps them gain weight and recover.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11462170

• Preventing Growth Problems in At-Risk Kids by Treating SIBO in Bangladesh

  Aimed at helping under-2 to 11-year-old children in urban Bangladesh, this study tests a treatment plan for small intestine bacterial overgrowth to improve growth and nutrition.

  NIH research University of Virginia · Charlottesville, United States · NIH-11417903

• NOURISH: Clinically Delivered Food Bank Support for Cancer Patients

  A program partners cancer centers with local food banks to deliver medically tailored food bags to patients in the clinic to support nutrition and health.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11380951

• Prioritizing food-system changes to help teens in low-income communities eat better

  This grant tests how to improve food access and choices for adolescents in low-income areas to prevent malnutrition and obesity.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11378176

• Better food access and nutrition for adolescents in low-income urban neighborhoods

  This project tries different food-system changes to help teens in low-income urban areas get affordable, healthy food and reduce both hunger and unhealthy weight.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11373822

• Improving food access and nutrition for teens in low-income neighborhoods

  This project will try community-led ways to make healthy food more available and affordable for teenagers living in low-income urban areas.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11373821

• Making healthy food easier to get for adolescents in low-income urban neighborhoods

  Researchers will work with teenagers, families, and communities to find practical ways to make healthy food more available and affordable for adolescents in low-income urban areas.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11373820

• Understanding why bile acid production falters in malnutrition

  This project explores why severe malnutrition in children disrupts the liver’s production of bile acids and how that harms growth and health.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11370173

• 3-D bedside scanning to track malnutrition in anorexia nervosa

  A bedside 3D optical scan method will help track malnutrition in adolescents with anorexia nervosa during hospitalization.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11368870

• Caregiver mental health and recovery after severe childhood malnutrition

  This project looks at whether depression and anxiety in caregivers are linked to how well young children recover and stay healthy after treatment for severe acute malnutrition in Burkina Faso.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11307658

• Harnessing mobile tech to improve adolescent nutrition in low-resource schools

  A school-based mobile health program for 10–14 year-olds in Tanzania aims to improve diet, activity, and anemia awareness using engaging digital content.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11307313

• Program to improve mothers' weight and children's growth in rural Guatemala

  This project offers combined food supplements and counseling to pregnant and postpartum women and their young children in rural Guatemala to help mothers reach healthy weights and support better child growth.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11251737

• Using monthly malaria pill visits to support children’s nutrition and health

  This project adds nutrition and other child-health services to the monthly malaria drug visits for young children in Burkina Faso to help them stay healthier during the rainy season.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11240334

• Finding better ways to diagnose tuberculosis in young children in Malawi.

  This study is looking for better ways to find tuberculosis in young children under five in Malawi, especially those who are very malnourished, to help improve their treatment and care.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11230626

• Azithromycin to help recovery in children with severe acute malnutrition

  This project compares a single dose of azithromycin, a course of amoxicillin, or a placebo to see which helps young children with uncomplicated severe acute malnutrition gain weight and recover better.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11229612

• Cancer center–food bank partnership providing medically tailored food bags to transplant and cell therapy patients

  This project links cancer centers with food banks to give medically tailored food bags during clinic visits to transplant and cellular therapy patients who struggle with food access.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11195727

• An automated system to identify malnutrition in cancer patients early

  This study is working on a smart system that helps find out if cancer patients are not getting enough nutrition by looking at their CT scans and answering some questions, so we can catch any problems early and help them feel better.

  NIH research Biosensics, LLC · Newton, UNITED STATES · NIH-11193066

• Helping adolescents in low-income areas get healthy food

  This project aims to understand and improve how adolescents in low-income countries can access and afford healthy foods to prevent both undernutrition and obesity.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11181156

• Understanding how malnutrition affects bile acid production

  This project explores why severe malnutrition in children prevents the body from making enough bile acids, which are crucial for absorbing nutrients and growing.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11098567

• Using malaria prevention methods to also tackle malnutrition in children

  This study is looking at how giving kids aged 3 to 59 months in Burkina Faso special malaria medicine during the rainy season can help not only prevent malaria but also improve their nutrition and health.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11053897

• Addressing malnutrition in mothers and children in Guatemala

  This study is looking for ways to help pregnant mothers in rural Indigenous communities in Guatemala gain healthy weight and ensure their children get enough nutrition, by providing food support and guidance to 766 families.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11047198

• Training leaders to address malnutrition and tuberculosis in Tanzania

  This study is creating a training program for scientists in Tanzania to help them tackle malnutrition and tuberculosis, so they can become strong leaders in improving health in their communities.

  NIH research University of Virginia · Charlottesville, United States · NIH-11040350

• Exploring how caregiver mental health affects children recovering from severe malnutrition

  This study looks at how a caregiver's feelings, like depression and anxiety, can affect how well children recover from severe malnutrition, and it’s for families in Burkina Faso who are going through this treatment together.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11031233

• Using azithromycin to help treat severe malnutrition in children

  This study is looking at whether adding azithromycin to the usual treatment helps children with severe acute malnutrition gain weight and get healthier, and it will involve kids in sub-Saharan Africa who are facing this challenge.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10997402

• Using milk-derived supplements to help children recover from diarrhea and malnutrition

  This study is looking at whether two milk-based supplements, lactoferrin and lysozyme, can help young children aged 6 to 24 months recover faster from diarrhea and malnutrition after being in the hospital.

  NIH research University of Washington · Seattle, United States · NIH-10991382

• Optimizing malaria treatment for children with severe malnutrition and adults with HIV

  This study is looking at the best way to give malaria medications to young children with severe malnutrition and adults with HIV, to make sure they get the right dose for effective treatment and prevention of malaria.

  NIH research Kamuzu University of Health Sciences · Blantyre, Malawi · NIH-10979190

• Using rice bran in therapeutic foods to treat childhood malnutrition

  This study is looking at how adding rice bran to special foods for kids with severe malnutrition can help them get better by improving their gut health and reducing the chances of getting sick again.

  NIH research Colorado State University · Fort Collins, United States · NIH-10750478

Related topics

Quick answers

How many Malnutrition clinical trials are recruiting right now?

39, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (5 trials), China (5 trials), France (4 trials), Switzerland (4 trials), Spain (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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