Nutritional support for patients with Critical Limb Ischemia

Perioperative Nutritional Optimization in Patients With Critical Limb Ischemia

Early Phase 1 Interventional Boston Medical Center · NCT03529019

This study tests if giving nutritional supplements to patients with Critical Limb Ischemia before and after surgery can help them recover better and feel stronger.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorBoston Medical Center Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT03529019 on ClinicalTrials.gov

What this trial studies

This pilot study investigates the effects of nutritional supplements on vascular surgery patients suffering from Critical Limb Ischemia (CLI), a condition often associated with malnutrition. The research aims to evaluate the nutritional and functional status of these patients through objective lab assessments and hand grip strength tests. By providing perioperative nutritional supplements, the study seeks to enhance the patients' nutritional status, potentially leading to improved clinical outcomes following surgery. The study is part of the Enhanced Recovery After Surgery protocol, which emphasizes the importance of nutrition in surgical recovery.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with Critical Limb Ischemia.

Not a fit: Patients who are pregnant, lactating, or have advanced chronic kidney disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve recovery and health outcomes for patients with Critical Limb Ischemia.

How similar studies have performed: While there is limited research specifically on vascular surgery patients, other studies have shown that nutritional optimization can improve outcomes in general surgical populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Critical Limb Ischemia

Exclusion Criteria:

* Female patients who are pregnant or lactating
* Chronic Kidney Disease Stages 4 and 5
* Patients who are on dialysis

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Critical Limb IschemiaMalnutritionNutritional SupplementsEnhanced Recovery After Surgery Protocol
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.