Using washed microbiota transplantation to treat malnutrition

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effects of washed microbiota transplantation (WMT) on patients suffering from malnutrition. It focuses on the relationship between gut microbiota and malnutrition, highlighting how the diversity of gut bacteria differs in malnourished individuals compared to healthy ones. The study aims to assess whether dietary interventions combined with WMT can improve nutritional status, weight gain, and overall health outcomes in malnourished patients. Participants will include adults who have experienced significant weight loss or have a low body mass index (BMI).

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥18 years old;
2. Meet any of the following two conditions: ①weight loss (\>5% weight loss in the past 6 months or \>10% weight loss in more than 6 months); ②low BMI (\<70 years old and BMI\<18.5kg/m2 or ≥70 years old and BMI\<22kg/m2);
3. Underwent washed microbiota transplantation.

Exclusion Criteria:

1. Expected survival time \<3 months;
2. Women who are pregnant or breastfeeding;
3. Other patients deemed not suitable for enrollment by the investigator.

Where it's running

• Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Principal investigator: Faming Zhang, PhD — The Second Hospital of Nanjing Medical University
• Study coordinator: Faming Zhang, PhD
• Email: fzhang@njmu.edu.cn
• Phone: 086-025-58509883

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Hospital-based look at infants under 6 months with acute malnutrition

  This study follows hospitalized infants under 6 months with acute malnutrition to see how common it is and how they grow during treatment.

  Recruiting at 16 sites Universitas Indonesia · Denpasar, Bali and 15 other locations · NCT07831343

• Preoperative Immunonutrition for bone and soft tissue sarcoma patients

  This study tests whether a short course of an oral nutrition supplement before surgery can help patients with bone or soft tissue sarcomas recover better after major tumor-related surgery.

  Recruiting St. Anne's University Hospital Brno, Czech Republic · Brno · NCT07609329

• Even protein distribution plus exercise for people awaiting liver transplant

  This trial tests whether spreading daily protein evenly and combining it with a 12-week exercise program improves nutrition, muscle mass, and function in people waiting for a liver transplant compared with uneven protein timing or usual advice.

  Recruiting at 2 sites Agricultural University of Athens · Athens, Attica and 1 other locations · NCT07561138

• Preoperative Oral Nutrition for Frail Elderly Hip Fracture Patients

  This observational study tests whether giving preoperative oral nutrition helps frail elderly patients with femur fractures fare better around surgery.

  Recruiting Duzce University · Düzce · NCT07463352

• Nutritional care for adults with type 2 or drug-induced diabetes who are malnourished or at risk

  This observational study will follow adults with type 2 or drug-induced diabetes who are malnourished or at risk to see if taking a diabetes-specific high-calorie, high-protein oral supplement with soluble fiber helps their nutrition, blood sugar, and quality of life.

  Recruiting at 12 sites Outcomes'10 · Santander, Cantabria and 11 other locations · NCT07252765

• Body composition monitoring for people with IBD starting biologic or JAK inhibitor therapy

  This project will use bioelectrical impedance to track lean mass percentage and phase angle over one year in adults with moderate-to-severe Crohn's disease or ulcerative colitis who are starting biologic or JAK inhibitor treatment.

  Recruiting Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Barcelona · NCT07162701

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.