Improving health before colorectal cancer surgery for older patients with malnutrition

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of nutrition prehabilitation alone versus nutrition combined with supportive exercise for older colorectal cancer patients who are malnourished and have low physical function. The study focuses on patients aged 65 and older who are scheduled for primary colorectal surgery and have a six-minute walking distance (6MWD) of less than 400 meters. By addressing malnutrition, the researchers aim to improve patients' physical performance before surgery, potentially enhancing surgical outcomes. The trial will measure adherence to interventions and the impact on achieving a clinically significant improvement in walking distance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 65 years and older;
* Patients with cancer scheduled for primary colorectal resection;
* Patients with 6MWD at baseline less than 400 m;
* Patients with Patient-Generated Subjective-Global Assessment (malnutrition assessment) score equal or greater than 9.

Exclusion Criteria:

* Patients with history of premorbid conditions that contraindicate exercise including dementia, -Parkinson's disease or previous stroke with paresis;
* Metastatic cancer;
* Patients who do not speak English or French and cannot be accompanied by someone who speaks English or French;

Where it's running

• MUHC Research Ethics Board
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Chelsia Gillis, RD PhD — McGill University
• Study coordinator: Chelsia Gillis, RD PhD
• Email: chelsia.gillis@mcgill.ca
• Phone: 514-398-7905

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.