Preoperative Oral Nutrition for Frail Elderly Hip Fracture Patients
Official title: Evaluation of the Effects of Preoperative Oral Nutritional Support on Hemodynamic Stability, Morbidity, Mortality, and Anthropometric Measurements in Patients With Femur Fractures and High Frailty Index: A Prospective Observational Study
Run by Duzce University · NCT07463352 · Data updated 2026-11-12
This observational study tests whether giving preoperative oral nutrition helps frail elderly patients with femur fractures fare better around surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 228 (estimated) |
| Sponsor | Duzce University Academic / other |
| Locations | 1 site (Düzce) |
| Status | Recruiting |
| Started | March 12, 2026 |
| Main results expected | January 1, 2027 |
| Study ends | January 1, 2027 |
| Registry record updated | June 16, 2026 |
| Trial ID | NCT07463352 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 65+, with femur fractures, a Clinical Frailty Scale score of 5 or higher, and who are expected to require postoperative intensive care.
✕Probably not a fit
Patients without frailty or those who do not tolerate enteral nutrition may not experience benefit from preoperative nutrition.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study will compare frail adults aged 65 and older with femur fractures who receive preoperative oral nutritional support to those who follow routine diets. Hemodynamic stability during surgery and in the ICU, along with postoperative complications, mortality, and length of hospital stay, will be recorded. Participants will be followed for 30 and 90 days after surgery to assess outcomes, with nutritional status assessed at baseline. No assignment of treatment is made by investigators; groups reflect standard clinical practice at the host institution, Duzce University. The study aims to clarify whether preoperative nutrition can improve perioperative care in a population with high frailty and malnutrition risk.
Why it matters
Potential benefit: If successful, preoperative nutrition could improve stability around surgery and reduce complications and recovery time for frail elderly patients with hip fractures.
How similar studies have gone: Prior studies in older adults suggest nutrition can influence outcomes, but data specific to frail, surgically managed hip fracture patients are limited and further investigation is warranted.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 65 years or older hospitalized with a diagnosis of femur fracture * High frailty index (Clinical Frailty Scale ≥ 5) * Patients expected to require postoperative intensive care Exclusion Criteria: * Patients requiring preoperative intensive care * Patients unable to tolerate enteral nutrition * Patients with advanced liver or kidney failure * Patients unable to cooperate * Patients with neuromuscular disease * Patients with severe malnutrition according to NRS-2002 guidelines * Patients who refuse to participate
Where it's running
-
Duzce University Health Research Center
Düzce, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Özlem Ersoy Karka, Ass. Prof.
- Email: drozlemersoy@gmail.com
- Phone: +90 533 729 3978
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Even protein distribution plus exercise for people awaiting liver transplant
This trial tests whether spreading daily protein evenly and combining it with a 12-week exercise program improves nutrition, muscle mass, and function in people waiting for a liver transplant compared with uneven protein timing or usual advice.
-
Cognitive effects of stomach or esophagus cancer surgery
This study will see how often people who have surgery for stomach or esophagus cancer develop postoperative delirium and whether it is linked to preoperative depression, frailty, malnutrition, sarcopenia, or lower quality of life.
-
Does crunching sound affect eating pleasure in older adults who are frail or malnourished?
This study tests whether crunchy textures in cookies can enhance eating enjoyment for adults 65 and older who are frail, malnourished, or toothless.
-
Postprandial drop and frailty in older adults having planned noncardiac surgery
This study tests whether a drop in blood pressure after meals and frailty predict low blood pressure after anesthesia starts in adults 65 and older undergoing planned noncardiac surgery.
-
Frailty Training for Emergency Nurses in Morocco
This trial tests whether a four-module training program helps Moroccan emergency nurses recognize and care for frail older adults in the ER.
-
Physical Function and Fall Risk in Older Adults in Lalín's Frailty Prevention Program
This study will look at how physical function and fall risk change in people 70 and older who participate in a routine frailty and falls prevention program, by comparing assessments before and after the 8–12 week program.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.