Assessing nutritional status in gastric cancer patients using bioelectrical impedance analysis
MalnutritiOn Assessment With biOelectrical impedaNce Analysis in gastRic Cancer patIentS Undergoing Multimodal trEatment - MOONRISE Study
This study is testing if a special method can help doctors check the nutrition and body health of gastric cancer patients during their treatment to better support their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 125 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Medical University of Lublin Academic / other |
| Locations | 1 site (Lublin) |
| Trial ID | NCT05723718 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the nutritional status and body composition of gastric cancer patients undergoing multimodal treatment through bioelectrical impedance analysis. It will include 125 patients with locally advanced gastric adenocarcinoma, who will undergo four consecutive nutritional assessments during their treatment. The goal is to determine if this method can serve as a validated tool to support clinical decisions regarding patient care. By understanding the relationship between nutritional status and tumor regression, the study seeks to address the high rates of malnutrition in this patient population.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with histologically confirmed locally advanced gastric adenocarcinoma who are eligible for multimodal treatment.
Not a fit: Patients with early-stage gastric cancer, distant metastasis, or those who cannot undergo bioelectrical impedance analysis will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a reliable method for assessing nutritional status, potentially improving treatment outcomes for gastric cancer patients.
How similar studies have performed: While the use of bioelectrical impedance analysis in nutritional assessment is established, this specific application in gastric cancer treatment is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Histologically confirmed gastric adenocarcinoma (or undifferentiated carcinoma) 3. Stage II - III disease (cT2 cN+ and cT3-T4 cN+/-) based on the 8th edition of TNM classification 4. Qualification for multimodal treatment by the decision of the multidisciplinary tumor board Exclusion Criteria: 1. Early gastric cancer (cT1N0-3M0) scheduled for endoscopic treatment by multidisciplinary team 2. Gastric stump carcinoma 3. Distant metastasis 4. Upfront surgery 5. Other malignancies 6. Contraindications to bioelectrical impedance analysis (e.g., implanted cardiac devices, metal implants or pregnancy)
Where this trial is running
Lublin
- Medical University of Lublin — Lublin, Poland (Recruiting)
Study contacts
- Principal investigator: Zuzanna Pelc, PhD — Medical University of Lublin
- Study coordinator: Zuzanna Pelc, PhD
- Email: zuzannapelc@umlub.pl
- Phone: +48 81 531 81 26
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.