Condition

Quality of Life (QOL) clinical trials and research

• 24Clinical trials
• 14Countries

Newest Quality of Life (QOL) clinical trials

All recruiting trials (24)

• Active surveillance after immunotherapy for MMR-deficient colorectal and GI cancers

  This study looks at whether some patients with non-metastatic, MMR-deficient or MSI-H colorectal cancers can skip surgery after a strong response to immunotherapy.

  Recruiting at 3 sites University Hospital, Basel, Switzerland · Basel and 2 other locations · NCT07829081

• Effect of Resistance Training on Muscle Mass and Mental Health in Adults on Obesity Medication

  This study tests whether 60 minutes of resistance training twice a week for 3 months helps people on GLP-1 RAs keep muscle and feel mentally better.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07652333

• Posterior tibial nerve stimulation to help bowel function after rectal cancer surgery

  This trial tests whether posterior tibial nerve stimulation can improve fecal continence and quality of life for adults who had rectal cancer surgery.

  Recruiting at 2 sites Althaia Xarxa Assistencial Universitària de Manresa · Manresa, Barcelona and 1 other locations · NCT07632196

• Prehabilitation within ERAS for gynecologic oncology surgery

  This trial tests whether a pre-surgery program of tailored exercise, immunonutrition (Ocoxin), breathing exercises and psychological support combined with ERAS helps people having gynecologic cancer surgery recover faster and with fewer complications.

  Recruiting Aristotle University Of Thessaloniki · Thessaloniki · NCT07210164

• Psychosocial teleassistance programme for adults with spina bifida

  This study tests a 10-week group telecare psychological program to see if it improves self-esteem, social skills, and overall psychological well-being in adults with spina bifida.

  Recruiting University of Deusto · Bilbao, Bizkaia · NCT07178873

• Quality of life and medical care for long-term sarcoma survivors in Germany (PROSa+)

  This project will ask adults in Germany who were diagnosed with sarcoma at least five years ago to complete questionnaires and some interviews to see how cancer and its treatments affect their quality of life and medical care.

  Recruiting at 4 sites Technische Universität Dresden · Dresden, Saxony and 4 other locations · NCT07148193

• Early exercise-based rehabilitation for adults hospitalized with acute pulmonary embolism

  This trial tries an early, supervised exercise and education program for adults hospitalized with acute pulmonary embolism to see if it prevents long-term breathlessness and improves quality of life.

  Recruiting at 6 sites Insel Gruppe AG, University Hospital Bern · Aarau and 5 other locations · NCT07143539

• ICU rehabilitation for adults on invasive mechanical ventilation

  This project will look at rehabilitation approaches used in ICUs worldwide to see if they relate to outcomes for adults who have been on invasive mechanical ventilation for at least 48 hours.

  Recruiting Universita degli Studi di Genova · Genova, Italy · NCT07093125

• Remote nutritional prehabilitation for people with invasive cancer starting treatment

  This study will test whether low- versus high-intensity remote nutrition support helps adults with invasive cancer who are starting systemic treatment stick with their treatment and feel better.

  Recruiting University of Vermont Medical Center · Burlington, Vermont · NCT07072377

• Enhancing self-esteem in people with multiple sclerosis using the Lexical Association Technique

  This trial tests whether the Lexical Association Technique can improve well-being and quality of life for adults with recent MS diagnoses compared with a placebo-like control.

  Recruiting University Hospital, Grenoble · Grenoble · NCT07064291

• Cities for Better Health: Preventing Childhood Obesity in Chiba City, Japan

  This project tests a multi-component effort in schools and communities to see if it can lower BMI z-scores and improve health-related quality of life for children aged 6-12 in Chiba City.

  Recruiting Chiba University · Chiba, Chiba · NCT07061665

• Group EMDR therapy for ongoing traumatic stress after road traffic accidents

  This trial will try a group EMDR program to see if it reduces post-traumatic stress symptoms, depression, and anxiety and improves quality of life for adults aged 18–45 who had a road traffic accident 3 months to 10 years ago.

  Recruiting University of the Punjab · Lahore, Punjab Province · NCT07027930

• How local breast cancer treatments affect side effects and quality of life in Chinese patients

  This project will test how surgery and related treatments (chemotherapy, radiation, hormone or targeted therapy) affect side effects and daily quality of life for people with early-stage breast cancer in China.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality and 2 other locations · NCT07010939

• Compassion Strikes Back — support for LVAD patients and their caregivers

  This project tests whether brief informational handouts or a short meeting with a psychologist can help adult LVAD patients and their primary family caregivers feel less stressed and improve quality of life during the first two months after hospital discharge.

  Recruiting University of Florida · Gainesville, Florida · NCT06988995

• Music therapy to support humanized care for emergency nurses

  This program will try short music therapy sessions to see if they reduce stress and improve compassionate care for emergency department nurses at FSFB.

  Recruiting Fundación Santa Fe de Bogota · Bogotá, Bogota D.C. · NCT06939426

• Intensified follow-up to reduce bowel symptoms and improve life after rectal cancer surgery

  We will test whether an intensified follow-up program can reduce LARS symptoms and improve quality of life for people who have had rectal cancer surgery with a protective ileostomy.

  Recruiting at 4 sites Phase 3 University Hospital, Basel, Switzerland · Basel and 4 other locations · NCT06936774

• Feeding problems and quality of life in children with a tracheostomy tube

  The team will see if feeding and swallowing problems are linked to how children with tracheostomy tubes and their parents rate the child's quality of life.

  Recruiting Karolinska Institutet · Solna, Stockholm County and 1 other locations · NCT06893458

• Evaluating acupuncture for treating ADHD in children

  This study is testing whether acupuncture, combined with herbal treatment, can help children aged 6-12 with ADHD feel better compared to just herbal treatment alone.

  Recruiting The Third Affiliated Hospital of Beijing University of Chinese Medicine · Beijing, Chaoyang District · NCT06860763

• Comparing two methods for closing midline laparotomy incisions to prevent hernias

  This study is testing if using a special mesh along with a stitching method can help prevent hernias in people who have had surgery on their abdomen.

  Recruiting Sykehuset Innlandet HF · Hamar · NCT06858020

• Radiotherapy for Head and Neck Cancer with Simultaneous Integrated Boost

  This study is testing a new type of radiation therapy for people with head and neck cancer to see if it helps them live longer and feel better while causing fewer side effects.

  Recruiting Wuerzburg University Hospital · Würzburg, Bavaria · NCT06831903

• Using the AirSeal System for Robot-assisted Prostate Surgery

  This study tests if using the AirSeal system during robot-assisted prostate surgery can lead to better results, like shorter hospital stays and fewer complications, for men with prostate cancer compared to traditional methods.

  Recruiting at 2 sites Phase 4 Brazilian Institute of Robotic Surgery · Salvador, Estado de Bahia and 1 other locations · NCT06784986

• Cognitive effects of stomach or esophagus cancer surgery

  This study will see how often people who have surgery for stomach or esophagus cancer develop postoperative delirium and whether it is linked to preoperative depression, frailty, malnutrition, sarcopenia, or lower quality of life.

  Recruiting Karolinska Institutet · Huddinge · NCT06687291

• Extra pain relief after root canal treatment

  This study tests if an extra pain relief injection after a root canal can help people feel less pain and recover better compared to those who get a placebo or no extra anesthetic.

  Recruiting Phase 2 New York University · New York, New York · NCT06655454

• Electroacupuncture plus self-acupressure to improve quality of life during chemotherapy for early-stage breast cancer

  This trial tests whether adding electroacupuncture together with self-acupressure can improve quality of life for people with early-stage breast cancer who are receiving chemotherapy.

  Recruiting Affiliated Hospital of Qinghai University · Xining, Qinghai · NCT06601621

Related topics

Quick answers

How many Quality of Life (QOL) clinical trials are recruiting right now?

24, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (4 trials), China (3 trials), Switzerland (3 trials), Spain (2 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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