Using monthly malaria prevention visits to help prevent child malnutrition

Leveraging the seasonal malaria chemoprevention platform to address malaria and malnutrition

NIH-funded research University of California, San Francisco · NIH-11465099

This project uses monthly door-to-door malaria medicine deliveries to also provide extra care to young children in the Sahel to try to reduce both malaria and malnutrition.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11465099 on NIH RePORTER

What this research studies

During the rainy season in the Sahel, children face higher risks of malaria and malnutrition because mosquito exposure and food shortages overlap. The project will add co-interventions to the existing seasonal malaria chemoprevention (SMC) program, which delivers sulfadoxine-pyrimethamine and amodiaquine door-to-door to children aged 3–59 months. In a pilot trial in places like Burkina Faso, teams will deliver the combined package monthly during the high-transmission season and track child health outcomes such as malaria cases and weight gain. The aim is to learn whether using the SMC delivery system for extra services improves child survival and nutrition more than SMC alone.

Who could benefit from this research

Good fit: Ideal participants are children aged 3–59 months living in SMC-covered areas (for example, communities in Burkina Faso) during the rainy/high-transmission season.

Not a fit: Children older than 59 months, adults, or families living outside SMC-covered regions or outside the seasonal window are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this could lower child malaria cases and improve nutrition during the high-risk rainy season.

How similar studies have performed: Previous research has shown antimalarial treatment can help weight gain in malnourished children, but using SMC as a delivery platform for combined malaria–nutrition interventions is a newer, pilot approach.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.