Finding better ways to diagnose tuberculosis in young children in Malawi.
Tuberculosis in Malawian children under five years old: exploring non-invasive diagnostic strategies and the impact of malnutrition on treatment pharmacokinetics
This study is looking for better ways to find tuberculosis in young children under five in Malawi, especially those who are very malnourished, to help improve their treatment and care.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-11230626 on NIH RePORTER |
What this research studies
This research focuses on developing non-invasive diagnostic methods for tuberculosis (TB) in children under five years old in Malawi, particularly those suffering from severe acute malnutrition. The project aims to understand how malnutrition affects the treatment of TB and to improve detection strategies that can be implemented in low-resource settings. By combining mentorship and practical experiences, the research will enhance the candidate's ability to lead clinical studies that address these critical health issues in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under five years old in Malawi who are suspected of having tuberculosis and may also be experiencing malnutrition.
Not a fit: Patients outside of Malawi or those who are not under five years old may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic techniques and treatment protocols for tuberculosis in malnourished children, potentially saving lives.
How similar studies have performed: Other research has shown promise in developing non-invasive diagnostic methods for TB, indicating that this approach could be effective.
Where this research is happening
East Lansing, United States
- Henry Ford Health + Michigan State University Health Sciences — East Lansing, United States (Active)
Researchers
- Principal investigator: Vonasek, Bryan — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Vonasek, Bryan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.