Assessing muscle mass and strength in patients with cirrhosis
Official title: Prospective Observational Cohort Survey to Assess the Prevalence and Development of Sarcopenia and the Correlation of Muscle Mass and Outcome in Patients With Cirrhosis by Skeletal Muscle Ultrasound.
Run by University Hospital, Antwerp · NCT06345547 · Data updated 2026-11-12
This study is testing how muscle mass and strength change in people with cirrhosis to see how it affects their daily lives and health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University Hospital, Antwerp Academic / other |
| Locations | 1 site (Edegem, Antwerpen) |
| Status | Recruiting |
| Started | May 6, 2024 |
| Main results expected | September 30, 2027 |
| Study ends | March 31, 2028 |
| Registry record updated | May 1, 2026 |
| Trial ID | NCT06345547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with cirrhosis who are receiving follow-up care at the University Hospital of Antwerp.
✕Probably not a fit
Patients who have made a decision to stop further treatment or those with recent complete remission of malignancy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study aims to investigate the prevalence and progression of sarcopenia in patients with cirrhosis at the University Hospital of Antwerp. Participants will undergo ultrasound assessments of muscle mass in both upper and lower limbs, handgrip strength measurements, and malnutrition screenings. Additionally, a quality of life questionnaire will be administered to evaluate the impact of sarcopenia on daily living. The study will analyze correlations between muscle mass, clinical outcomes, and the etiology of cirrhosis.
Why it matters
Potential benefit: If successful, this study could enhance understanding of sarcopenia in cirrhosis, leading to improved management and treatment strategies for affected patients.
How similar studies have gone: Other studies have shown success in using ultrasound to assess muscle mass in various populations, indicating that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of cirrhosis and follow-up in the University Hospital of Antwerp Exclusion Criteria: * known patient will against participation in the study or against the measures applied in the study * a decision made prior to inclusion to stop further treatment of the patient within the next 24 hours * no complete remission of malignancy including hepatocellular carcinoma within the past 12 months
Where it's running
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University Hospital Antwerp
Edegem, Antwerpen, Belgium Recruiting
Study contacts
- Principal investigator: Karolien Dams, MD — University Hospital, Antwerp
- Study coordinator: Karolien Dams, MD
- Email: karolien.dams@uza.be
- Phone: +3238213635
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.