Condition

Bone Sarcoma clinical trials and research

• 12Clinical trials
• 1NIH research projects
• 12Countries

Newest Bone Sarcoma clinical trials

All recruiting trials (12)

• AYA Sarcoma Survivors: Personalized Exercise Program Pilot

  This pilot tests a personalized 12-week exercise program for adolescents and young adults with sarcoma to see if a triage tool can connect them with the right rehabilitation and exercise services.

  Recruiting at 3 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 2 other locations · NCT07662239

• Preoperative Immunonutrition for bone and soft tissue sarcoma patients

  This study tests whether a short course of an oral nutrition supplement before surgery can help patients with bone or soft tissue sarcomas recover better after major tumor-related surgery.

  Recruiting St. Anne's University Hospital Brno, Czech Republic · Brno · NCT07609329

• Zanzalintinib treatment for advanced leiomyosarcoma

  This study is testing if a new medication called zanzalintinib can help people with advanced leiomyosarcoma live longer without their cancer getting worse.

  Recruiting Phase 2 Northwestern University · Chicago, Illinois · NCT06571734

• Using a special dye to guide surgery for sarcoma removal

  This study is testing whether a special dye can help surgeons remove sarcomas more accurately by showing them where the cancer ends during surgery.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT06409013

• Assessing early psychiatric referral effects on mental health in sarcoma patients

  This study tests whether getting early mental health support helps sarcoma patients feel less anxious and depressed while recovering from surgery.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 7 other locations · NCT06129903

• Evaluating quality of life and functional outcomes in sarcoma patients after limb salvage surgery

  This study looks at how limb salvage surgery affects the quality of life and daily functioning of people aged 18 to 95 who have had surgery for bone or soft tissue sarcoma in their legs.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT05051059

• Comparing carbon ion therapy, surgery, and proton therapy for pelvic bone sarcomas

  This study is testing whether carbon ion therapy works better than surgery or proton therapy for treating pelvic bone sarcomas and how these treatments affect patients' quality of life.

  Recruiting at 3 sites Mayo Clinic · Scottsdale, Arizona and 2 other locations · NCT05033288

• Using regorafenib with supportive care for patients with high-grade bone sarcomas

  This study is testing if the drug regorafenib, along with supportive care, can help people aged 12 and older with high-grade bone sarcomas who haven't fully responded to standard treatment.

  Recruiting at 8 sites Phase 2 Centre Leon Berard · Besançon and 15 other locations · NCT04698785

• Quality assessment of sarcoma care in Europe and Latin America

  This study looks at how well patients with different types of sarcoma are treated in Europe and Latin America to see if care is better at expert centers and to find ways to improve outcomes.

  Recruiting at 7 sites Grupo Espanol de Investigacion en Sarcomas · Buenos Aires and 8 other locations · NCT04181970

• Using Regorafenib to Maintain Treatment Benefits After Initial Therapy for Bone Sarcomas

  This study is testing if the drug regorafenib can help people with bone sarcomas stay cancer-free longer after their initial treatment.

  Recruiting at 12 sites Centre Leon Berard · Besançon and 15 other locations · NCT04055220

• Evaluating recovery and function after bone cancer surgery

  This study looks at how well people recover and regain function after surgery for bone cancer, including the use of bone grafts or artificial devices, over three years.

  Recruiting at 5 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 4 other locations · NCT03442465

• New method to deliver chemotherapy directly into the lungs for sarcoma patients

  This study is testing a new way to deliver chemotherapy directly into the lungs during surgery for sarcoma patients to see if it can better target hidden cancer cells and improve their outcomes.

  Recruiting Phase 1 University Health Network, Toronto · Toronto · NCT02811523

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Helping young bone cancer survivors manage chronic pain with a mobile program

  This program offers a special mobile therapy and brain stimulation to help Black and Hispanic young people who have survived bone cancer find better ways to manage their long-lasting pain.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11323743

Related topics

Quick answers

How many Bone Sarcoma clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (6 trials), France (3 trials), Canada (1 trial), Argentina (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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