Condition

Hematopoietic Stem Cell Transplantation clinical trials and research

• 27Clinical trials
• 33NIH research projects
• 11Countries

Newest Hematopoietic Stem Cell Transplantation clinical trials

All recruiting trials (27)

• Population PK-guided ATG Dosing in Haploidentical Stem Cell Transplant

  This trial tests a population PK-guided ATG dosing strategy in people undergoing haploidentical hematopoietic stem cell transplantation to see if it improves outcomes.

  Recruiting Phase 3 Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT07862127

• Population PK-guided ATG Dosing in Haplo-HSCT

  This study tests a population PK-guided dosing strategy for anti-thymocyte globulin (ATG) in adults and adolescents undergoing haploidentical stem cell transplantation to see if it can reduce GVHD while keeping relapse risk acceptable.

  Recruiting Phase 2 Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT07791576

• Low-dose liposomal amphotericin B to prevent invasive fungal infections in neutropenic children

  This study tests whether giving a fixed low dose of liposomal amphotericin B can prevent invasive fungal infections in children aged 3–17 who are severely neutropenic after hematopoietic stem cell transplantation or similar high-risk conditions.

  Recruiting Haikou Affiliated Hospital of Central South University Xiangya School of Medicine · Haikou, Hainan · NCT07725263

• Personalized ATG dosing in unrelated donor stem cell transplants

  This trial tests whether tailoring anti-thymocyte globulin dosing works better than standard fixed dosing in adults and adolescents receiving unrelated donor stem cell transplants.

  Recruiting Phase 4 Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT07648992

• Hematologic cancer survivors after stem cell transplant try a personalized care plan

  This study tests a personalized Survivorship Care Plan for people with hematologic cancer who have undergone a stem cell transplant to see if it’s feasible within the Italian health system.

  Recruiting Azienda USL Reggio Emilia - IRCCS · Reggio Emilia · NCT07579065

• T-cell–guided letermovir stopping after allogeneic stem cell transplant

  This tests whether using a CMV-specific T-cell blood test to decide when adult CMV-positive patients can stop letermovir after allogeneic stem cell transplant keeps them protected while avoiding unnecessary drug exposure.

  Recruiting Phase 4 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Beijing, Beijing Municipality and 11 other locations · NCT07569653

• Etamsylate versus placebo to prevent bleeding after stem cell transplant

  This will test whether etamsylate can reduce bleeding in adults with very low platelets after hematopoietic stem cell transplantation.

  Recruiting Phase 3 First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT07442513

• Amimestrocel infusion to prevent severe mouth sores after allogeneic stem cell transplant

  This study will try a single IV infusion of Amimestrocel in adults receiving myeloablative allogeneic stem cell transplants with TBI or melphalan to see if it prevents severe mouth sores.

  Recruiting Phase 2 The First Affiliated Hospital of Soochow University · Suzhu, Jiangsu · NCT07400328

• Early zoledronate to prevent bone problems after pediatric stem cell transplant

  This pilot tests whether giving zoledronate early can prevent bone loss and fractures in children and teens undergoing or recovering from hematopoietic stem cell transplant who are at high risk.

  Recruiting Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07375290

• Cardiovascular outcomes after hematopoietic stem cell transplantation

  We will collect clinical, laboratory, and treatment data from people who had hematopoietic stem cell transplants to see if certain factors are linked to heart and blood vessel problems after transplant.

  Recruiting at 16 sites Peking University People's Hospital · Beijing, Beijing Municipality and 15 other locations · NCT07349498

• Preventing graft rejection after allogeneic stem cell transplant

  This trial will try the drug emapalumab to see if it can prevent graft rejection in people judged high risk after allogeneic hematopoietic stem cell transplant.

  Recruiting Early Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07244419

• Investigating immune cells in acute graft-versus-host disease

  This study is looking at how certain immune cells affect the development and progression of acute graft-versus-host disease in people who have had a stem cell transplant.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Other (Non U.s.) · NCT06708507

• Digital avatar support for people having outpatient stem cell transplants

  This trial will test whether a conversational avatar (care.coach) can reduce anxiety and improve quality of life for adults undergoing outpatient allogeneic stem cell transplant.

  Recruiting Friendi.fi Corporation · Boston, Massachusetts · NCT06564233

• Support for returning to work after stem cell transplantation

  This study is testing a program to help people who have had stem cell transplants get back to work and deal with any challenges they face in doing so.

  Recruiting MGH Institute of Health Professions · Boston, Massachusetts · NCT06494423

• Comparing two types of stem cell transplants for children

  This study is testing whether a new type of stem cell transplant can reduce complications and improve life for children who need this treatment.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06423131

• Identifying blood markers for early diagnosis of transplant-related complications

  This study is trying to find blood markers that can help doctors spot early signs of a serious complication called TA-TMA in patients who have had a stem cell transplant.

  Recruiting Institute of Hematology & Blood Diseases Hospital, China · Tianjin · NCT06102694

• Depletion of specific immune cells for stem cell transplantation in young patients

  This study is testing a new way to prepare stem cells for children and young adults with blood cancers by removing certain immune cells to see if it helps them have a safer and more effective transplant from unrelated donors.

  Recruiting Nationwide Children's Hospital · Columbus, Ohio · NCT06082947

• Using low-power laser therapy to prevent mouth pain in stem cell transplant patients

  This study is testing if different types of low-power laser therapy can help prevent mouth pain in patients getting stem cell transplants.

  Recruiting at 2 sites Phase 3 Instituto Nacional de Cancer, Brazil · Rio de Janeiro, Rio de Janeiro and 1 other locations · NCT06071637

• Investigating taste, smell, and sensory functions in patients undergoing stem cell transplantation

  This study is trying to see how stem cell transplants affect taste and smell in patients and how these changes might impact their quality of life.

  Recruiting University of Oslo · Oslo, Oslo · NCT06003660

• Using Inotuzumab Ozogamicin to treat MRD-positive ALL after stem cell transplant

  This study is testing if a new treatment called Inotuzumab Ozogamicin can help young adults with a type of leukemia who have had a stem cell transplant and are facing a return of their disease.

  Recruiting Phase 2 The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT05940961

• Evaluating narsoplimab for treating TMA in children after stem cell transplants

  This study is testing a new treatment called narsoplimab to see if it can help children who are at high risk for blood vessel problems after getting stem cell transplants.

  Recruiting at 4 sites Phase 2 Omeros Corporation · San Diego, California and 15 other locations · NCT05855083

• Culturally tailored yoga program for cancer patients undergoing stem cell transplantation

  This study is testing a special yoga program designed for cancer patients getting stem cell transplants to see if it helps them feel better and supports their cultural needs.

  Recruiting at 3 sites M.D. Anderson Cancer Center · Houston, Texas and 2 other locations · NCT05681026

• Lower dose of cyclophosphamide for preventing complications after blood stem cell transplants

  This study is testing if a lower dose of a medication called cyclophosphamide can help prevent complications after blood stem cell transplants for patients while keeping them safe and healthy.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Duarte, California and 1 other locations · NCT05436418

• Allogeneic stem cell transplant for VEXAS Syndrome

  This study is testing if a stem cell transplant can help people with VEXAS Syndrome feel better and improve their health.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05027945

• Evaluating nutrition in patients after stem cell transplantation

  This study looks at the nutrition of patients who have had stem cell transplants to see how their eating habits and health changes affect their recovery over time.

  Recruiting The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT04146870

• Long-term follow-up for patients who had a stem cell transplant

  This study is checking in on people who had a stem cell transplant to see how they are doing long-term and to help improve their care.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03000244

• Collecting and storing umbilical cord blood for transplantation

  This study is collecting and storing umbilical cord blood from newborns to help patients who need bone marrow transplants find a match.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT01728545

NIH-funded research (33)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Gentle electrical stimulation to keep muscles strong during stem cell transplant

  This project uses small, gentle electrical pulses to try to help Veterans keep muscle strength and reduce fatigue during and after stem cell transplants for blood cancers.

  NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-11511692

• Inpatient yoga therapy for cancer patients undergoing stem cell transplant

  A randomized trial will test whether an inpatient yoga program helps people receiving stem cell transplants feel better and cope with treatment.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11447334

• A structured peer support program for people having stem cell transplants

  A brief, supportive, phone-based peer program for adults with blood cancers undergoing stem cell transplant to help manage stress and improve recovery.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11447086

• T Cell Precursors to Restore Immune Power After Stem Cell Transplants

  This grant supports a patient-friendly approach to speed up immune recovery after a stem cell transplant by giving patients donor‑made T cell precursors that mature into healthy immune cells.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11438593

• Engineering patient avatars to study GVHD after bone marrow transplant

  Researchers are creating patient-specific lab models of the gut, liver, and blood to better understand and prevent GVHD after bone marrow transplant, with a focus on children.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11428942

• Optimizing stem cell transplants to treat non-malignant blood diseases

  A researcher is pursuing a five-year plan to improve stem cell transplantation strategies for non-cancer blood illnesses, with a focus on safer conditioning, better stem cell collection, and gene editing.

  NIH research Washington University · Saint Louis, United States · NIH-11392266

• Positive psychology support for stem cell transplant survivors

  A phone-delivered program helps people who survived stem cell transplantation feel less anxious or depressed and enjoy a higher quality of life.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11383135

• Optimizing Blood Stem Cell Transplants for Blood C cancers and related diseases

  This grant supports improving how stem cell transplants are collected and given, with the goal of better outcomes and fewer side effects for people with blood cancers and some autoimmune or inherited conditions.

  NIH research Washington University · Saint Louis, United States · NIH-11370616

• Acceptance and Commitment Therapy to boost resilience and function after stem cell transplant

  A patient-facing program tests whether Acceptance and Commitment Therapy helps people who had an allogeneic stem cell transplant feel better and stay more active.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11337293

• BMT-CARE: Support for caregivers of stem cell transplant patients

  A caregiver-focused program uses practical strategies to help families and friends manage stress and daily responsibilities while a loved one undergoes stem cell transplantation.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11311917

• How healthy blood stem cells might help in Alzheimer's

  Researchers are using a mouse model of Alzheimer's to test whether transplanting healthy blood-forming stem cells can prevent memory loss and brain damage.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11295487

• Early lung screening after pediatric stem-cell transplant using inhaled xenon MRI

  This tests a special inhaled xenon MRI scan to find early lung problems in children who have had a hematopoietic stem-cell transplant.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11257352

• Home treatment for cancer patients using their own stem cells

  This study is exploring a new way for older cancer patients to get stem cell treatment at home instead of in a hospital, with daily visits from healthcare providers to offer personalized support and make the experience easier for both patients and their caregivers.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11251676

• How family half-matched (haplo) stem cell donors feel after donation

  This project looks at the experiences and well-being of parents and other half-matched donors and how doctors decide to use these donors for people needing blood stem cell transplants.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11241956

• Improving Stem Cell Transplants for Blood Cancers and Other Diseases

  This work aims to make stem cell transplants safer and more effective for people with blood cancers, autoimmune diseases, and other serious conditions.

  NIH research Washington University · Saint Louis, United States · NIH-11228615

• Boosting virus-fighting T cells after stem cell transplant by removing CD52

  This project tests if virus-targeting T cells edited to lack CD52 can survive and control infections better in adults after a hematopoietic stem cell (bone marrow) transplant, even when patients receive the immune-suppressing drug alemtuzumab.

  NIH research Children's Research Institute · Washington, United States · NIH-11184362

• Tailored exercise plus NAD+ supplement to rebuild muscle and fitness in adolescent and young adult stem-cell transplant survivors

  This project tests whether a personalized home exercise program combined with an NAD+ precursor supplement helps teenage and young adult stem-cell transplant survivors regain muscle mass and fitness.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11176198

• Phone-based positive psychology program for stem cell transplant survivors

  A brief phone program that teaches gratitude, strengths, and meaning to help lower anxiety and depression and improve quality of life for people who survived hematopoietic stem cell transplants.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11135383

• Support program for caregivers of patients undergoing stem cell transplantation

  This study is testing a supportive program called BMT-CARE to help caregivers of patients getting stem cell transplants by offering them helpful tools and guidance to manage their feelings and challenges during this tough time.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11086774

• Impact of SIRPalpha differences on stem cell transplant outcomes

  This study is looking at how differences in a protein called SIRPα between blood cancer patients and their stem cell donors can affect the success of their transplants, with the goal of finding ways to improve transplant outcomes and help patients live healthier lives.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11052538

• IL-33 and IL-9–producing innate immune cells in lung injury after pediatric bone marrow transplant

  Researchers are looking at how an immune signal called IL-33 and certain immune cells that make IL-9 affect lung injury in children after allogeneic stem cell (bone marrow) transplants.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11017702

• Understanding the quality of life for donors in half-matched stem cell transplants

  This study looks at how donating stem cells affects the health and well-being of donors, especially parents compared to siblings, to help improve support for them during the transplant process.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11010784

• Detecting lung problems in children after stem cell transplants using advanced MRI techniques.

  This study is looking at a new way to spot lung problems early in kids who have had a stem cell transplant, using a special type of MRI that makes it easier for them, so they don’t have to do the usual lung tests; the aim is to catch any issues sooner to help keep their lungs healthy.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11010031

• Improving T cell therapy for viral infections after stem cell transplants

  This study is looking at a new way to make virus-fighting T cells work better for patients who have had a stem cell transplant, by using a special technique to help these cells survive the medications that weaken the immune system, which could lead to better protection against viral infections.

  NIH research Children's Research Institute · Washington, United States · NIH-10991125

• Improving stem cell transplants for treating blood disorders

  This study is looking at new ways to make stem cell transplants safer and more effective for people with blood disorders like sickle cell disease, and it may involve patients trying out these improved methods.

  NIH research Washington University · Saint Louis, United States · NIH-10984824

• Using electrical stimulation to help maintain physical function during stem cell transplants

  This study is looking at whether a special electrical stimulation treatment can help veterans recovering from blood cancer treatments keep their strength and feel better during their recovery.

  NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-10938029

• Improving muscle mass and fitness in young cancer survivors through exercise and supplements

  This study is designed to help young people who have had stem cell transplants stay strong and healthy by combining personalized exercise programs with special supplements, making it easier for them to keep their muscle and fitness levels up at home.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-10914104

• Identifying and preventing severe lung complications after stem cell transplants

  This study is looking to help patients who are getting a stem cell transplant by finding ways to predict and prevent a serious lung problem called acute respiratory distress syndrome (ARDS), so they can have a smoother recovery.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10909914

• Improving fatigue management after stem cell transplants

  This study is looking for ways to help people who feel very tired after receiving a stem cell transplant for blood disorders, and it offers a chance for patients to try out new strategies that could improve their energy and overall well-being.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10908583

• Tracking antibiotic resistance in patients after stem cell transplants

  This study is looking at how antibiotic-resistant bacteria grow and spread in patients who have had stem cell transplants, with the hope of finding ways to prevent infections and keep you healthier.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10898755

• Controlling immune responses to improve outcomes after stem cell transplants

  This study is looking at ways to help patients with acute myeloid leukemia have safer and more effective stem cell transplants by finding out how to better manage the immune system and reduce complications like graft-versus-host disease.

  NIH research Stanford University · Stanford, United States · NIH-10864817

• Improving mental health for survivors of stem cell transplants

  This study is testing a friendly phone program called PATH that helps people who have had stem cell transplants feel better by managing anxiety and depression, while also improving their overall quality of life.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10861113

• Investigating how IL-33 affects lung injury after stem cell transplants in children

  This study is looking at how certain immune cells and a protein called IL-33 might cause lung problems in kids who have had a stem cell transplant, with the goal of finding better ways to help them breathe easier and stay healthy after their treatment.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-10756116

Related topics

Quick answers

How many Hematopoietic Stem Cell Transplantation clinical trials are recruiting right now?

27, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in China (13 trials), United States (11 trials), Norway (1 trial), Germany (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 3: 3, Phase 4: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →