Improving mental health for survivors of stem cell transplants

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

NIH-funded research Brigham and Women's Hospital · NIH-10861113

This study is testing a friendly phone program called PATH that helps people who have had stem cell transplants feel better by managing anxiety and depression, while also improving their overall quality of life.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10861113 on NIH RePORTER

What this research studies

This research focuses on a phone-delivered positive psychological intervention called PATH, designed to help survivors of hematopoietic stem cell transplantation (HSCT) manage anxiety and depression while enhancing their quality of life. The intervention consists of short, accessible sessions that encourage practices like gratitude and personal strengths, making it easier for patients to engage without the need for in-person visits or extensive training. By addressing the psychological challenges faced by HSCT survivors, this project aims to provide a supportive resource that can be integrated into their recovery process.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have undergone hematopoietic stem cell transplantation and are experiencing symptoms of anxiety or depression.

Not a fit: Patients who have not undergone HSCT or those who do not experience psychological distress may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this research could significantly improve the mental health and overall quality of life for HSCT survivors.

How similar studies have performed: Previous research has shown that positive psychological interventions can effectively improve mental health outcomes, suggesting that this approach may yield beneficial results for HSCT survivors as well.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
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Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.