Understanding the quality of life for donors in half-matched stem cell transplants
Official title: Donor health-related quality-of-life and physician decision-making in the context of haploidentical hematopoietic stem cell transplantation (HaploQOL)
Funded at University of Pittsburgh at Pittsburgh · NIH-11010784 · Data updated 2026-11-12
This study looks at how donating stem cells affects the health and well-being of donors, especially parents compared to siblings, to help improve support for them during the transplant process.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | January 15, 2024 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $523,673 |
| NIH project number | 5R01HL171117-02 |
| Project ID | NIH-11010784 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are considering or have undergone haploidentical stem cell transplantation, particularly those with a parent or child as their donor.
✕Less likely to help
Patients who are not involved in haploidentical stem cell transplantation or do not have a haploidentical donor may not benefit from this research.
What this research studies
This research investigates the health-related quality of life (HRQoL) of donors who provide stem cells for haploidentical hematopoietic stem cell transplantation (HSCT). It focuses on the experiences of these donors, particularly in parent-child relationships, and how these experiences may differ from sibling donors. The study aims to gather data on the physical and emotional impacts of donation, as well as how physicians make decisions regarding donor selection. By understanding these factors, the research seeks to improve the overall transplantation process and donor support.
Why it matters
Potential benefit: If successful, this research could enhance the support and care provided to stem cell donors, leading to better outcomes for both donors and recipients.
How similar studies have gone: Previous research has shown promising results in understanding donor experiences in stem cell transplantation, indicating that this area of study is both relevant and necessary.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Switzer, Galen E. — University of Pittsburgh at Pittsburgh
- Study coordinator: Switzer, Galen E.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.