NIH-funded research R37 grant

Phone-based positive psychology program for stem cell transplant survivors

Official title: Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

Funded at Brigham and Women's Hospital · NIH-11135383 · Data updated 2026-11-12

A brief phone program that teaches gratitude, strengths, and meaning to help lower anxiety and depression and improve quality of life for people who survived hematopoietic stem cell transplants.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 9, 2024
Project endJune 30, 2029
Funding year2025
Award (this year)$681,935
NIH project number5R37CA288557-02
Project IDNIH-11135383 on NIH RePORTER

Who could benefit from this research

Could help

Adults who have undergone hematopoietic stem cell transplantation and are experiencing psychological distress or lower quality of life would be the intended participants.

Less likely to help

People without a history of stem cell transplantation, those who are medically unstable, or those who require intensive psychiatric treatment may not benefit from this brief phone program.

What this research studies

If you join, you would take part in a tailored, phone-delivered program with short 15–20 minute sessions that teach exercises to build gratitude, personal strengths, and meaning. Trained interventionists from diverse backgrounds deliver the structured activities by phone so the program is more accessible than long in-person therapies. The project tracks changes in anxiety, depression, and overall quality of life over time to see whether these brief sessions help HSCT survivors feel better and function better in daily life.

Why it matters

Potential benefit: If successful, this program could reduce anxiety and depression and improve overall quality of life for hematopoietic stem cell transplant survivors.

How similar studies have gone: Positive psychology approaches have shown benefits in other cancer survivor groups, but a tailored, brief phone program for HSCT survivors is a newer, less-tested approach.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Amonoo, Hermioni L. — Brigham and Women's Hospital
  • Study coordinator: Amonoo, Hermioni L.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.