Condition

Acute Graft Versus Host Disease clinical trials and research

• 13Clinical trials
• 3Countries

Newest Acute Graft Versus Host Disease clinical trials

All recruiting trials (13)

• Moxibustion with second-line treatment for steroid-refractory acute graft-versus-host disease after transplant

  This study will test whether adding moxibustion to standard second-line drug therapy helps people aged 14–65 with steroid-refractory gastrointestinal acute GVHD after an allogeneic stem cell transplant.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07572669

• Post-transplant dental cleaning to prevent chronic graft-versus-host disease

  This will try a dental cleaning about 28 days after an allogeneic stem cell transplant to see if it lowers the chance of chronic graft-versus-host disease in adult transplant recipients.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07535008

• First-line jaktinib plus corticosteroids for acute graft-versus-host disease

  This trial will test whether adding jaktinib to standard steroids helps adults with grade II–IV acute graft-versus-host disease after an allogeneic stem cell transplant.

  Recruiting Phase 1/2 First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT07285889

• Timing of umbilical cord blood infusion and risk of acute graft-versus-host disease after transplant

  This trial will test whether giving a single-unit unrelated umbilical cord blood transplant at different times of day changes the chance of acute graft-versus-host disease in people with malignant blood disorders who are in remission.

  Recruiting Phase 3 Anhui Provincial Hospital · Hefei, Anhui · NCT07047456

• Ruxolitinib treatment for acute graft-versus-host disease

  This study is testing if ruxolitinib can help people with acute graft-versus-host disease who haven't improved with regular steroid treatments.

  Recruiting at 10 sites Phase 2 Icahn School of Medicine at Mount Sinai · Duarte, California and 13 other locations · NCT06936566

• Using human chorionic gonadotropin to treat acute graft versus host disease

  This study is testing if adding a hormone called hCG to standard steroid treatment can help people with acute graft versus host disease feel better after their stem cell transplant.

  Recruiting Phase 2 Hospital Universitario Dr. Jose E. Gonzalez · Monterrey, Nuevo León · NCT06904599

• Preventing severe acute graft‑versus‑host disease in high‑risk adults with an anti‑CD25 antibody

  This trial will try a recombinant humanized anti‑CD25 antibody to prevent severe aGVHD in adults the daGOAT model flags as intermediate‑to‑high risk after allogeneic stem cell transplant.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT06880419

• Universal T-cell therapy for treating severe aGVHD

  This study is testing a new type of T-cell therapy to see if it can help people with severe acute graft-versus-host disease who haven't responded to standard treatments after a stem cell transplant.

  Recruiting at 2 sites Phase 1 First Affiliated Hospital of Zhejiang University · Fuzhou, Fujian and 1 other locations · NCT06750133

• Investigating immune cells in acute graft-versus-host disease

  This study is looking at how certain immune cells affect the development and progression of acute graft-versus-host disease in people who have had a stem cell transplant.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Other (Non U.s.) · NCT06708507

• Timing the donor stem cell infusion to reduce acute graft-versus-host disease after donor blood stem cell transplant

  This trial tests whether changing the clock time when donor peripheral blood stem cells are given can lower the risk and severity of acute graft-versus-host disease in people aged 12–60 having their first allogeneic peripheral blood stem cell transplant for nonmalignant blood disorders.

  Recruiting at 6 sites Phase 3 Anhui Provincial Hospital · Hefei, Anhui and 5 other locations · NCT06294691

• Mini-dose MTX combined with standard-dose steroids for treating acute GVHD

  This study is testing if a low dose of methotrexate combined with standard steroids can help people with acute graft-versus-host disease feel better compared to just using the standard steroids alone.

  Recruiting at 2 sites Phase 3 Peking University People's Hospital · Beijing, Beijing Municipality and 1 other locations · NCT05921305

• Using leflunomide with steroids to treat acute graft-versus-host disease after stem cell transplant

  This study is testing if adding leflunomide to steroid treatment can help people with acute graft-versus-host disease after a stem cell transplant feel better and reduce their symptoms.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05443425

• Using fecal microbiota to treat gut acute graft-versus-host disease

  This study is testing whether fecal microbiota transplantation can help improve gut symptoms in patients with acute graft-versus-host disease after stem cell transplantation.

  Recruiting The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT03148743

Related topics

Quick answers

How many Acute Graft Versus Host Disease clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (9 trials), United States (3 trials), Mexico (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 3, Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →