Collecting and storing umbilical cord blood for transplantation
The Collection and Storage of Umbilical Cord Blood for Transplantation
This study is collecting and storing umbilical cord blood from newborns to help patients who need bone marrow transplants find a match.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250000 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT01728545 on ClinicalTrials.gov |
What this trial studies
This study aims to collect blood samples from the umbilical cords of newborns immediately after delivery and store them in the MD Anderson Cord Blood Bank. The collected cord blood may be included in the National Cord Blood Inventory, which supports the collection of cord blood for patients needing bone marrow transplants. The samples will be made available to patients through the National Marrow Donor Program, potentially aiding those without a suitable donor. The collection process is safe and does not pose any risk to the mother or baby.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women aged 18 or older who can provide informed consent.
Not a fit: Patients who are not pregnant or those under 18 years of age will not benefit from this study.
Why it matters
Potential benefit: If successful, this initiative could significantly increase the availability of cord blood for patients requiring life-saving transplants.
How similar studies have performed: Other studies have shown success in utilizing cord blood for transplantation, indicating a promising approach in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria 1. Pregnant women age 18 or older. Cord blood will not be collected from a minor. 2. Able to give verbal informed consent prior to collection of the cord blood. 3. Able to give written informed consent prior to collection of the cord blood. 4. Willing to provide a personal and family medical history (if available) of herself and the biologic father (if available), prior to or following collection of the cord blood. 5. Willing to consent to testing of her blood and the cord blood for infectious diseases, including human immunodeficiency virus (HIV), human T cell lymphotrophic virus (HTLV), hepatitis B and C, cytomegalovirus (CMV), syphilis (RPR), Trypanosoma cruzi (Chagas) and West Nile Virus (WNV). Incomplete tests or positive infectious disease testing results may result in the cord blood unit being deemed unacceptable for clinical use. 6. Willing to consent to testing the cord blood for HLA type, ABO/RhD type, newborn screening and microbial cultures. Exclusion Criteria: N/A
Where this trial is running
Houston, Texas
- MD Anderson Cord Blood Bank Collection Sites — Houston, Texas, United States (Recruiting)
Study contacts
- Study coordinator: Elizabeth Shpall, MD
- Email: eshpall@mdanderson.org
- Phone: 713-745-2161
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.