Improving fatigue management after stem cell transplants
Official title: Reducing Persistent Fatigue Following Hematopoietic Stem Cell Transplantation
Funded at Massachusetts General Hospital · NIH-10908583 · Data updated 2026-11-12
This study is looking for ways to help people who feel very tired after receiving a stem cell transplant for blood disorders, and it offers a chance for patients to try out new strategies that could improve their energy and overall well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $176,063 |
| NIH project number | 5K23HL159328-04 |
| Project ID | NIH-10908583 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have undergone hematopoietic stem cell transplantation and are experiencing persistent fatigue.
✕Less likely to help
Patients who have not undergone stem cell transplantation or do not experience fatigue may not benefit from this research.
What this research studies
This research focuses on developing and testing interventions to help patients who experience persistent fatigue following hematopoietic stem cell transplantation. The approach includes evidence-based strategies aimed at improving patient outcomes and quality of life for those with blood disorders. The project involves mentorship from experts in behavioral interventions and cancer care, ensuring a comprehensive training plan for the principal investigator. Patients may participate in randomized clinical trials designed to assess the effectiveness of these interventions.
Why it matters
Potential benefit: If successful, this research could significantly reduce fatigue and improve the quality of life for patients recovering from stem cell transplants.
How similar studies have gone: Previous research has shown promise in using behavioral interventions to manage fatigue in cancer patients, suggesting potential success for this approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Nelson, Ashley — Massachusetts General Hospital
- Study coordinator: Nelson, Ashley
Related research
Other NIH-funded projects on the same topics.
-
Telehealth exercise program to help rural breast cancer survivors fight fatigue
A telehealth exercise program is being tested to reduce cancer-related fatigue in rural breast cancer survivors.
-
DESCANSO: A friendly CBT plan to ease depression, sleep problems, and fatigue in Latino cancer patients
A Spanish-speaking CBT program called DESCANSO is being tested to help Latino cancer patients feel less tired, sleep better, and happier.
-
Gentle electrical stimulation to keep muscles strong during stem cell transplant
This project uses small, gentle electrical pulses to try to help Veterans keep muscle strength and reduce fatigue during and after stem cell transplants for blood cancers.
-
Time-restricted eating for fatigue and frailty in people with cancer
A 12-week study will test whether eating within a daily 10-hour window helps reduce fatigue and slow frailty in people living with advanced cancer.
-
Inpatient yoga therapy for cancer patients undergoing stem cell transplant
A randomized trial will test whether an inpatient yoga program helps people receiving stem cell transplants feel better and cope with treatment.
-
A structured peer support program for people having stem cell transplants
A brief, supportive, phone-based peer program for adults with blood cancers undergoing stem cell transplant to help manage stress and improve recovery.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.