Condition
Breast Carcinoma clinical trials and research
As of November 12, 2026, Find a Trial lists 75 Breast Carcinoma clinical trials that are recruiting, at sites in 16 countries (most in United States (57), France (3), Italy (3)). By phase: Phase 2 (12), Phase 3 (4), Phase 1 (4), Early Phase 1 (1). The most active sponsors are Mayo Clinic (13), National Cancer Institute (NCI) (7), City of Hope Medical Center (6). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 75Clinical trials
- 16Countries
Newest Breast Carcinoma clinical trials
All recruiting trials (75)
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Mobile health navigation to improve breast cancer screening in Kenyan women
This study tests m-Health patient navigation tools to help women in Kenya access breast cancer screening and early detection services.
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Blended e-Health Program to Help Women with Breast or Gynecologic Cancer Manage Fear of Cancer Progression
This trial tests a blended online and group program to see if it helps women with breast or gynecologic cancer feel less fear that their cancer could grow or spread.
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Environmental exposure checks in high-risk and early-onset breast cancer care
This study tests how patients and providers feel about using environmental exposure risk data in breast cancer care for women at average/high risk or with early-onset breast cancer.
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CSF sample collection from people with metastatic breast cancer to see brain metastasis risk
This study tests whether spinal fluid and other samples can help predict brain metastases in adults with metastatic HER2-positive or triple-negative breast cancer who have not yet shown brain involvement.
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Body composition and outcomes after breast reconstruction
This study will see if detailed body composition measurements can help predict complications after mastectomy with immediate breast reconstruction in adult women.
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Support tool for women with HR+ breast cancer on long-term endocrine therapy
This study tests a SHIELD web- and app-based portal to help women with hormone receptor–positive breast cancer manage symptoms while on long-term endocrine treatment.
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Personalized Exercise Plan for Breast Cancer Survivors on Chemotherapy
This trial tests whether adding a guided exercise program to a healthy-lifestyle education plan helps breast cancer patients undergoing chemotherapy maintain fitness, heart health, and quality of life.
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Sleep Changes and Biomarkers After Breast Cancer Treatment
This project will see how sleep patterns and stress-related biological markers change from treatment through survivorship in people with stage I–III hormone receptor–positive breast cancer.
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In-home cancer treatment with remote specialist support for patients in the Florida Panhandle
This program will try giving standard cancer treatments at home to people living in the Florida Panhandle and nearby areas to see if they prefer it and have better treatment satisfaction.
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Combining tissue, imaging, and genetic information to improve breast cancer risk prediction
This research tests whether combining pathology, radiology, and genetic data can better predict future breast cancer risk for women who previously had a benign breast biopsy at Mayo Clinic.
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Breast cancer screening for women with moderate genetic or estimated lifetime risk
This project will see if women aged 30–74 with certain moderate-risk gene variants or a 20–40% lifetime risk follow recommended annual breast MRI and mammogram screening.
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ENLIGHT algorithm to find treatment options for advanced metastatic breast cancer
This test uses the ENLIGHT algorithm to try to find approved drugs that might work better for adults with triple-negative or endocrine therapy–resistant metastatic breast cancer.
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Personalized 3D-printed external breast prosthesis after mastectomy
This trial will try a custom 3D-printed external breast prosthesis to see if it improves patient-reported outcomes for people who had a mastectomy and did not have reconstruction.
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Radiology-based prediction of HER2 level and T‑DXd benefit in metastatic breast cancer
This study tests whether patterns in CT or FDG‑PET images can show HER2 level and help predict response to trastuzumab deruxtecan for people with metastatic breast cancer.
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Immune checkpoint washout for axillary lymph node staging in invasive ductal breast cancer
This test sees if washing axillary lymph nodes for immune checkpoint markers can help find cancer spread in people with invasive ductal breast cancer who are scheduled for neoadjuvant therapy.
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Vanguard: a new blood test approach to screen for multiple cancers
This study will test two different blood-based multi-cancer detection tests in adults 45–75 without cancer to see if they find cancers earlier than usual care.
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Using advanced MRI techniques to improve breast cancer detection
This study is testing a new type of MRI that doesn't use contrast dye to see if it can help find and understand breast cancer better in women who are at higher risk or have concerning results.
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Ultra‑short whole-breast radiation with lumpectomy cavity boost for stage I–III breast cancer
This trial will test whether a very short course of whole‑breast radiation with a boost to the lumpectomy cavity works well and is safe for women age 40 and older with stage I–III breast cancer who had breast‑conserving surgery.
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Collecting patient experiences of skin reactions in breast cancer radiotherapy
This study is trying to learn about the skin reactions that breast cancer patients experience during or after radiation treatment to help improve their care.
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From exclusion to inclusion: understanding and reconnecting breast cancer patients who stopped follow-up
This project will try outreach by phone, message, or email to see if women treated for non-metastatic breast cancer at a Hyderabad tertiary centre who stopped follow-up can be re-engaged.
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A decision aid to help breast cancer patients make chemotherapy choices
This study tests a smartphone tool to help breast cancer patients who have nerve pain from chemotherapy make better choices about their treatment.
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Omitting full axillary dissection when breast cancer has spread to armpit nodes
The trial tests whether removing only the sentinel and known cancerous lymph nodes is as safe as removing many more armpit nodes in people with breast cancer and armpit node involvement.
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Using fucoidan to prevent fatigue in cancer patients undergoing chemotherapy
This study tests if a seaweed supplement called fucoidan can help cancer patients undergoing chemotherapy feel less tired.
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High-resolution imaging to check if tumors are completely removed during surgery
This study is testing if high-resolution imaging during surgery can help make sure all tumors are removed in patients with different types of cancer, like breast, prostate, and thyroid, to improve their treatment outcomes.
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Post-treatment support program to help Black women breast cancer survivors in Western New York transition into survivorship
This program tries group sessions and one-on-one peer mentoring to help Black women breast cancer survivors in Western New York adjust to life after finishing treatment.
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Predicting outcomes for advanced breast cancer patients treated with CDK4/6 inhibitors and endocrine therapy
This study is trying to see how well different CDK4/6 inhibitors combined with hormone therapy work for people with advanced breast cancer and how safe they are.
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Measuring circulating mutation burden (cfMB) in women with BRCA mutations and their sisters
This trial will test whether a blood test that measures circulating mutation burden (cfMB) differs between cancer-free women who carry a BRCA1/2 mutation and their non-carrier sisters.
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Evaluating patient outcomes and satisfaction after mastectomy care at Mayo Clinic Florida's Care Hotel
This study looks at how women feel and recover after mastectomy surgery when they stay at a special Care Hotel compared to those who go home or stay in a regular hospital.
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Decision-making tool to help women with early breast cancer choose treatment
This project will test a patient decision aid to help women with early-stage breast cancer make treatment choices.
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Postoperative radiation therapy for intermediate-risk breast cancer
This study is testing if a specific type of radiation therapy after surgery can help people with intermediate-risk breast cancer have better outcomes.
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Radiation before mastectomy with immediate breast reconstruction
This trial tests whether giving radiation before mastectomy combined with immediate breast reconstruction improves cosmetic results and quality of life for women who need mastectomy and post‑mastectomy radiation.
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Phytocannabinoids to reduce chronic chemotherapy-related nerve pain in breast and colon cancer survivors
This will test whether daily CBD or a combined THC:CBD treatment can reduce long-term nerve pain, tingling, and numbness in people who survived breast or colon cancer.
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Partial breast reconstruction using chest wall perforator flaps
This study looks at how well partial breast reconstruction using chest wall flaps works for women who have had surgery for early-stage breast cancer.
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Program to increase cancer screening among low-income women in Central Ohio
This study is trying to see if a new program can help low-income women in Central Ohio get better access to cancer screenings for breast, cervical, and colorectal cancers.
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Hypofractionated radiotherapy for non-metastatic breast cancer treatment
This study is testing if giving a shorter course of radiation therapy before or after surgery can help women with non-metastatic breast cancer while causing fewer severe side effects.
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Combining TIL therapy and immunotherapy for advanced breast cancer
This study is testing a new treatment that combines a special type of immune cell therapy with a drug called Pembrolizumab to see if it can help people with advanced breast cancer.
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Improving access to genetic testing for underserved cancer patients
This study is testing whether a computer character can give better information about genetic testing to underserved cancer patients compared to regular human healthcare providers.
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Examining the effects of cannabis use in cancer patients undergoing treatment
This study is trying to see how using cannabis affects newly diagnosed cancer patients who are starting treatment for their illness.
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A program to help women navigate breast cancer care
This study tests a support program designed to help underserved women with breast cancer find the care they need and improve their quality of life.
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Evaluating blood tests for breast cancer diagnosis
This study is testing a blood test for breast cancer to see if it works as well as traditional mammograms for diagnosing the disease.
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Using tart cherry juice to prevent nerve damage from chemotherapy in breast cancer patients
This study is testing if drinking tart cherry juice can help prevent nerve damage in breast cancer patients receiving chemotherapy.
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Collecting samples and data from patients with recurrent or metastatic breast cancer
This study is collecting blood and tissue samples from patients with recurrent or metastatic breast cancer to learn more about the disease and improve treatment options.
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Treatment of Breast Cancer with Alpha Radiation in Elderly or Frail Patients
This study is testing a new type of radiation treatment for breast cancer to see if it's safe and effective for older or frail patients.
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Using PET scans and biomarkers to guide treatment for metastatic breast cancer
This study is testing if using special scans and blood tests can help doctors choose the best treatment for women with a specific type of advanced breast cancer.
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Using low dose tamoxifen with or without omega-3 fatty acids to reduce breast cancer risk
This study is testing whether adding omega-3 fatty acids to low dose tamoxifen can help reduce the risk of breast cancer in overweight or obese postmenopausal women.
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Finding the best dose of tamoxifen to reduce breast cancer risk in premenopausal women
This study is testing if a higher dose of tamoxifen can help premenopausal women at higher risk for breast cancer by reducing breast density on mammograms.
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Using contrast enhanced ultrasound to identify breast masses
This study is testing if a special type of ultrasound with a contrast agent can help doctors tell the difference between harmless and harmful breast lumps to reduce unnecessary biopsies for patients with certain types of breast masses.
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Program to prevent lymphedema after breast cancer surgery
This study is testing a prevention program to help women who have breast cancer surgery avoid lymphedema by using treatments like lymphatic massage and special garments.
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Activating the immune response to treat advanced colorectal and breast cancer
This study is testing a new immune treatment combined with radiation to see if it can help people with advanced colorectal or breast cancer that can't be surgically removed.
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Partnered exercise program for couples during cancer treatment
This study tests whether a partnered exercise program can help couples stay healthy during radiation treatment for breast and prostate cancer compared to just receiving exercise information.
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New bispecific antibody treatment for colorectal cancer
This study is testing a new antibody treatment for people with advanced colorectal cancer who haven't had success with other therapies to see if it can help their immune system fight the cancer better.
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Using advocates to boost lung cancer screening rates
This study is testing if having advocates and support can help more people get screened for lung cancer by addressing their concerns and encouraging them to share information with others.
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Comparing acolbifene and low dose tamoxifen to prevent breast cancer in high-risk premenopausal women
This study is testing whether acolbifene or low dose tamoxifen can help prevent breast cancer in high-risk premenopausal women.
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Home-based breathing exercises to reduce side effects in breast cancer treatment
This study is testing if a 12-week home breathing exercise program can help breast cancer patients feel better by reducing heart and lung side effects from chemotherapy.
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Aerobic training for women undergoing chemotherapy for breast cancer
This study tests whether standard or adjustable aerobic training helps women undergoing chemotherapy for breast cancer improve their fitness levels.
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Using 3D ultrasound to evaluate lymph nodes in breast cancer patients
This study is testing a new 3D ultrasound technology to see if it can better identify lymph nodes in breast cancer patients compared to the standard 2D ultrasound.
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Using low-dose aspirin to prevent postpartum breast cancer
This study is testing if taking low-dose aspirin can help lower the risk of breast cancer in new mothers who are about to have a breast biopsy.
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Understanding TRPC6 to Prevent Heart Issues in Breast Cancer Patients Receiving Chemotherapy
This study is trying to see if looking at a specific gene can help prevent heart problems in breast cancer patients who are getting chemotherapy.
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Assessing immune changes in breast cancer patients after radiation therapy
This study is testing how radiation therapy affects the immune system in breast cancer patients by looking at changes in immune cells and DNA damage before and after treatment.
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Vaginal CO2 laser for vaginal dryness in breast cancer survivors
This trial will test whether a vaginal fractional CO2 laser can reduce vaginal dryness in women who have finished breast cancer treatment.
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Evaluating how diet affects breast cancer risk
This study is trying to see if the way women eat affects their risk of getting breast cancer, especially for those who are already at high risk.
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Examining the effects of tamoxifen on immune response in breast cancer patients
This study is testing how tamoxifen affects the immune response in breast cancer patients to see if it changes the way their body fights cancer and handles treatment side effects.
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Comparing synthetic mammography to full-field digital mammography for breast cancer detection
This study is testing if synthetic mammography can find breast cancer better and with fewer follow-up appointments than traditional digital mammography.
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Effects of white button mushroom on inflammation in obese postmenopausal women at high risk of breast cancer
This study is testing if eating white button mushrooms every day for three months can help reduce inflammation and improve immune health in obese postmenopausal women who are at high risk for breast cancer.
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New ultrasound method for detecting and monitoring breast cancer
This study tests a new ultrasound method to see if it can better detect breast cancer and track how well treatment is working for patients with suspicious breast lumps.
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Understanding immune changes in breast and ovarian cancer patients
This study looks at how the immune system changes in women with breast and ovarian cancer to find ways to make treatments work better.
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Genetic testing for cancer in diverse ethnic groups
This study is testing how genetic testing can help cancer patients from different ethnic backgrounds understand their risks and improve their personalized care.
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Using photoacoustic imaging to examine breast tissue in cancer patients and healthy individuals
This study is testing a new imaging technique that uses light and sound to see if it can help tell the difference between healthy breast tissue and cancer in women.
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Registry for metastatic breast cancer in Austria
This study is collecting information from people with metastatic breast cancer in Austria to better understand the disease and how different treatments are working.
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Imaging with a new radioactive tracer for solid tumors
This study is testing a new imaging method using a special radioactive tracer to see if it can help find tumor cells in patients with solid tumors like ovarian and breast cancers, while also looking at how safe it is and how it relates to certain genetic factors.
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Collecting data and samples from women undergoing routine mammograms for breast cancer research
This study is collecting health information and blood samples from 10,000 women getting routine mammograms to help researchers learn more about breast cancer and women's health over time.
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Identifying genetic variants linked to nerve damage in breast cancer patients treated with paclitaxel
This study is trying to find out if certain genetic factors make breast cancer patients more likely to experience nerve damage after receiving the chemotherapy drug paclitaxel.
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Finding genetic variants in patients with heart failure undergoing breast cancer treatment
This study is trying to find genetic changes in patients who have heart failure while being treated for breast cancer to help improve future treatments and understand their risks better.
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Identifying genetic variants linked to hypertension in breast cancer patients treated with bevacizumab
This study is trying to find out if certain genetic traits make breast cancer patients more likely to develop high blood pressure while being treated with a drug called bevacizumab.
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Collecting data on side effects of proton therapy for cancer treatment
This study is trying to learn about the side effects that cancer patients experience after receiving proton therapy to help improve future treatments.
Related topics
Quick answers
How many Breast Carcinoma clinical trials are recruiting right now?
75, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 16 countries. The most sites are in United States (57 trials), France (3 trials), Italy (3 trials), Belgium (2 trials), China (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 12, Phase 3: 4, Phase 1: 4, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.