Condition
Prostate Carcinoma clinical trials and research
As of November 12, 2026, Find a Trial lists 38 Prostate Carcinoma clinical trials that are recruiting, at sites in 5 countries (most in United States (34), Brazil (1), India (1)). 1 was first registered in the last 30 days. By phase: Phase 2 (11), Early Phase 1 (2), Phase 3 (2), Phase 4 (1). The most active sponsors are Mayo Clinic (7), Jonsson Comprehensive Cancer Center (5), City of Hope Medical Center (3). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 38Clinical trials
- 1New in 30 days
- 5Countries
Newest Prostate Carcinoma clinical trials
All recruiting trials (38)
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Understanding NK Cell Function in Prostate Cancer Across Races
This study tests whether natural killer (NK) cells behave differently in prostate cancer patients of diverse racial backgrounds by analyzing blood and tissue samples.
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MRI or CT planning to guide high-dose-rate prostate brachytherapy
This trial tests whether adding an MRI to CT-based treatment planning for HDR prostate brachytherapy changes urinary side effects in men with localized prostate cancer.
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Targeted Early Detection for Men at High Genetic Risk for Prostate Cancer
This study tests urinary biomarkers and PSA to see if they can improve early detection for men with a strong family or genetic risk for prostate cancer.
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Urine and MRI approach to find aggressive prostate cancer early
This study tests whether a urine test called MPS2, paired with MRI, can better detect aggressive prostate cancer in men 50–75 at risk, possibly reducing unnecessary biopsies.
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GET FIT Together: a socially enhanced exercise program for older men with prostate cancer
This program tests whether adding structured social support to supervised online exercise reduces cancer-related loneliness and improves mental and physical health in men 65 and older who have had prostate cancer.
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Improved MRI methods to distinguish benign from cancerous pelvic findings
This test tries new deep-learning image-processing methods on MRI scans to get clearer images faster for adults scanned for prostate screening or suspected endometriosis.
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Decision support to help germline genetic testing for men with prostate cancer
A tool is being tested to help men with prostate cancer decide about germline genetic testing and see if it increases testing completion.
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In-home cancer treatment with remote specialist support for patients in the Florida Panhandle
This program will try giving standard cancer treatments at home to people living in the Florida Panhandle and nearby areas to see if they prefer it and have better treatment satisfaction.
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Metabolic strategies — time‑restricted eating, GLP‑1 medicines, and a heart‑healthy diet to protect heart and metabolic health during hormone therapy for prostate cancer
This trial tests whether time‑restricted eating or GLP‑1 drugs (semaglutide or tirzepatide), combined with heart‑healthy diet counseling, can protect heart and metabolic health in men receiving androgen‑deprivation therapy for prostate cancer.
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Flotufolastat F18 PET/CT to find residual or recurrent prostate cancer after focal therapy
This test will see if flotufolastat F18 PET/CT can find prostate cancer that remains or comes back in men after focal therapy.
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New PSMA PET/CT (flotufolastat F-18) compared with MRI to find prostate cancer
We are testing whether a PSMA PET/CT scan using flotufolastat F-18 can better guide targeted prostate biopsies in men with prostate cancer who have a suspicious MRI lesion (PI-RADS 3-5).
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MRI-based machine learning versus radiologist reads to detect prostate cancer
This trial tests whether MRI-based AI methods can find clinically significant prostate cancer as well as experienced radiologists in men getting a prostate biopsy or prostate removal surgery.
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Remote robotic prostate surgery using telesurgery technology
This trial will try using robotic telesurgery—where a specialist operates remotely over a secure internet link—for adults who need robotic prostate surgery.
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Virtual Reality support for Black men newly diagnosed with prostate cancer
This trial tests a VR-enabled, AI-guided support tool to help Black men newly diagnosed with prostate cancer feel more supported and manage emotional and practical needs.
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Vanguard: a new blood test approach to screen for multiple cancers
This study will test two different blood-based multi-cancer detection tests in adults 45–75 without cancer to see if they find cancers earlier than usual care.
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Fezolinetant to reduce hot flashes in men on androgen-deprivation therapy
This trial will test whether taking fezolinetant once daily for 4 weeks reduces how often and how severe hot flashes are in men with prostate cancer who are on androgen-deprivation therapy.
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Examining MRI Features to Improve Prostate Cancer Diagnosis
This study is trying to see if special MRI pictures can help doctors better diagnose prostate cancer in men with high PSA levels or abnormal exams, aiming to reduce unnecessary biopsies and improve patient care.
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18F-rhPSMA-7.3 PET-mpMRI to guide targeted prostate biopsy with TRUS‑MR fusion
This phase II trial tests whether adding an 18F-rhPSMA-7.3 PET scan to standard mpMRI helps find clinically significant prostate cancer in men scheduled for prostate biopsy.
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Shorter hormone therapy combined with radiotherapy for high-risk prostate cancer
This study is testing if a shorter hormone therapy combined with radiotherapy can help men with high-risk prostate cancer do better and feel better than the usual two-year hormone treatment.
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Breathing practice to improve brain and mental health in cancer and MS patients
This study tests whether breathing exercises through a mobile app can help improve brain and mental health for people with cancer and multiple sclerosis, along with their caregivers.
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Using the AirSeal System for Robot-assisted Prostate Surgery
This study tests if using the AirSeal system during robot-assisted prostate surgery can lead to better results, like shorter hospital stays and fewer complications, for men with prostate cancer compared to traditional methods.
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Using shockwave therapy to improve erectile function after prostate cancer surgery
This study is testing whether using shockwave therapy along with a common erectile dysfunction medication can help men regain erectile function better after prostate cancer surgery.
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Comparing RapidPlan and human-driven planning for prostate cancer radiation therapy
This study is testing if a new computer-based tool for planning radiation therapy can work as well as traditional methods for prostate cancer patients while causing fewer side effects.
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Improving prostate health in Black communities through community engagement
This study is testing a new program to help Black men get better access to prostate health services and screenings by comparing it to a regular setup at different community locations.
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Flexible dosing of 177Lu-PSMA-617 for advanced prostate cancer treatment
This study is testing if a flexible schedule for a prostate cancer treatment can help men with advanced cancer live longer and feel better compared to the usual fixed schedule.
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Reducing bowel side effects by changing proton beam spot placement for prostate cancer
This will test whether deleting proton beam spots near the rectum and small bowel during pencil-beam proton therapy lowers bowel and bladder side effects in men with low- or intermediate-risk prostate cancer.
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Observational study of men with advanced prostate cancer
This study is collecting blood, urine, and health information from men with advanced prostate cancer to help researchers learn more about the disease and improve future treatments.
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Partnered exercise program for couples during cancer treatment
This study tests whether a partnered exercise program can help couples stay healthy during radiation treatment for breast and prostate cancer compared to just receiving exercise information.
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Online weight loss and exercise program for prostate cancer survivors
This study is testing an online weight loss and exercise program to see if it helps men with prostate cancer who have had hormone therapy feel healthier and improve their quality of life.
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Using bright white light therapy to reduce fatigue and depression in advanced prostate cancer patients
This study is testing if bright white light therapy can help reduce fatigue and depression in men with advanced prostate cancer who are receiving treatment.
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Combining pembrolizumab with targeted radionuclide therapy for advanced prostate cancer
This study is testing if combining pembrolizumab with a targeted radiation treatment can help men with advanced prostate cancer live longer and feel better after other treatments have stopped working.
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Using light and occupational therapy to manage fatigue in cancer patients
This study is testing if combining light therapy with occupational therapy can help cancer patients with genitourinary cancers feel less tired and improve their daily activities.
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MRI-guided ultrasound treatment for intermediate grade prostate cancer
This study is testing a new ultrasound treatment for men aged 45 to 80 with intermediate grade prostate cancer to see if it safely destroys tumor cells and helps them recover better than surgery.
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Androgen therapy with or without niraparib for high-risk prostate cancer after radiation
This study is testing whether adding the drug niraparib to hormone therapy after radiation can help men with high-risk prostate cancer do better than hormone therapy alone.
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Exploring the use of a new imaging agent in prostate cancer surgery
This study is testing a new imaging agent to see if it can help doctors find cancerous lymph nodes during prostate cancer surgery.
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Improving prostate cancer classification using MRI and AI
This study is testing whether using advanced MRI scans and artificial intelligence can help doctors better identify and classify prostate cancer.
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Community health coach program to improve access to germline genetic testing for African American men with prostate cancer
This project will test whether culturally tailored education from a community-based health coach helps African American men with advanced prostate cancer understand and use germline genetic testing.
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Prostate cancer screening for those with genetic risk
This study is testing how regular check-ups and sample collections can help find prostate cancer earlier in people with a genetic risk for aggressive forms of the disease.
Related topics
Quick answers
How many Prostate Carcinoma clinical trials are recruiting right now?
38, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in United States (34 trials), Brazil (1 trial), India (1 trial), China (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 11, Early Phase 1: 2, Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.