New ultrasound method for detecting and monitoring breast cancer
Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
Mayo Clinic · NCT04799535
This study tests a new ultrasound method to see if it can better detect breast cancer and track how well treatment is working for patients with suspicious breast lumps.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 550 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT04799535 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates a novel breast ultrasound technique aimed at improving the diagnosis of breast cancer and monitoring treatment response. It involves pre-biopsy patients with suspicious breast masses and those undergoing neoadjuvant chemotherapy or endocrine therapy. The study will assess the diagnostic performance of this ultrasound method against pathology results and compare its effectiveness in predicting treatment response to traditional MRI. Participants will undergo multiple ultrasound assessments throughout their treatment process.
Who should consider this trial
Good fit: Ideal candidates include adult patients aged 18 and older with suspicious breast masses or those diagnosed with breast cancer undergoing neoadjuvant therapy.
Not a fit: Patients with breast implants or conditions that prevent the effective use of ultrasound will not benefit from this study.
Why it matters
Potential benefit: If successful, this method could enhance early detection and monitoring of breast cancer, leading to better patient outcomes.
How similar studies have performed: Other studies have shown promise in using ultrasound for breast cancer detection, but this specific approach is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * AIM 1: Patient volunteers, ages \>= 18 with suspicious breast masses scheduled for breast biopsy, or at least two weeks or more after breast biopsy * AIM 2: Patient volunteers, ages \>= 18 who have biopsy proven breast cancer and are going under neoadjuvant chemotherapy and/or endocrine therapy had their baseline MRI and/or ultrasound Exclusion Criteria: * Patients with breast implants or any condition that does not allow proper use of ultrasound (US)
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: Azra Alizad, M.D. — Mayo Clinic in Rochester
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Breast Carcinoma, Breast Neoplasm