Using photoacoustic imaging to examine breast tissue in cancer patients and healthy individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the use of photoacoustic imaging to analyze breast tissue in women with breast cancer and healthy subjects. The primary objective is to identify specific photoacoustic features that indicate breast malignancy and assess treatment responses. Participants will undergo imaging sessions lasting 30 minutes, with the option to repeat the procedure up to ten times on separate days. This innovative approach combines light and sound to enhance the understanding of breast tissue characteristics, particularly in dense breasts where traditional mammography may be less effective.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women with clinically suspicious or confirmed breast cancer masses (that have not been surgically removed) and will/have already undergo/undergone breast magnetic resonance imaging (MRI).

Exclusion Criteria:

* Pregnant women (there are no known risks to these procedures, but any unforeseen risks are as yet undetermined, so pregnant women will be excluded by means of a verbal confirmation at time of screening).
* Women who have had breast implants in the previous 6 months.
* Women who have had lumpectomy
* Adults unable to consent.
* Individuals who are not yet adults (infants, children, teenagers).
* Pregnant women.
* Prisoners.
* There is no direct benefit of the study to any subject either non-English or English speaker. To facilitate the consent process, we will exclude non-English speaking subjects.

Where it's running

• Roswell Park Cancer Institute
  Buffalo, New York, United States Recruiting

Study contacts

• Principal investigator: Ermelinda Bonaccio — Roswell Park Cancer Institute

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.