Sleep Changes and Biomarkers After Breast Cancer Treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study follows people with stage I–III hormone receptor–positive breast cancer from after primary surgery through survivorship to track sleep and related biomarkers. Participants wear a wrist actigraphy device, provide cheek swab, saliva, and hair samples, complete repeated surveys, and allow review of medical records. Researchers will analyze actigraphy-measured sleep duration and self-reported sleep quality over time and link these measures to sociodemographic, treatment, social support, and built environment factors, with attention to race, ethnicity, and underserved communities. The study will also examine associations between sleep and markers of biological aging, stress, and inflammation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \* Age \>= 18 years old at time of breast cancer diagnosis

  * Stage I to III breast cancer diagnosis
  * Hormone receptor positive breast cancers
  * Post primary surgery, before chemotherapy/radiation therapy begins
  * No known evidence of breast cancer recurrence (local or distant) or second, primary cancer
  * No prior history of new other malignancy since their breast cancer diagnosis (other than non-melanoma skin cancer)
  * Able to speak, understand and read English
  * Cognitively able to complete the study requirements
  * Ability to access medical records from treating hospital

Exclusion Criteria:

* \* Stage IV or metastatic breast cancer

  * Not cognitively able to provide informed consent
  * Not willing to provide informed consent

Where it's running

• Ohio State University Comprehensive Cancer Center
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Electra Paskett, MSPH, PhD, FAACR — Ohio State University Comprehensive Cancer Center
• Study coordinator: The Ohio State University Comprehensive Cancer Center
• Email: OSUCCCClinicaltrials@osumc.edu
• Phone: 800-293-5066

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.