Partial breast reconstruction using chest wall perforator flaps

PartBreCon-Pro Study: PARTial BREast RECONstruction With Chest Wall Perforator Flap, a PROspective Study of Clinical and Patient Reported Outcomes

Cambridge University Hospitals NHS Foundation Trust · NCT06728527

This study looks at how well partial breast reconstruction using chest wall flaps works for women who have had surgery for early-stage breast cancer.

Quick facts

Study typeObservational
Enrollment1001 (estimated)
Ages18 Years and up
SexFemale
SponsorCambridge University Hospitals NHS Foundation Trust (other)
Locations1 site (Cambridge, Cambridgeshire)
Trial IDNCT06728527 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the outcomes of partial breast reconstruction utilizing chest wall perforator flaps following breast conservation surgery for early-stage breast cancer. It will collect data on patient demographics, tumor characteristics, and treatment details, including surgical and oncological interventions. The study focuses on understanding how these factors influence surgical planning and patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients undergoing partial breast reconstruction for primary breast cancer who have previously undergone breast conservation surgery.

Not a fit: Patients who are undergoing volume displacement breast conservation surgery or mastectomy with or without immediate reconstruction may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could improve aesthetic outcomes and patient satisfaction after breast conservation surgery.

How similar studies have performed: Other studies have explored similar surgical techniques, indicating potential for positive outcomes, but this specific approach may offer novel insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing partial breast reconstruction using CWPF for primary breast cancer
* Delayed correction of breast deformity following previous BCS
* Each surgeon is to have performed a minimum of 10 CWPFs
* Each centre anticipates completing a minimum of 10/year

Exclusion Criteria:

* Patients undergoing volume displacement BCS
* Patients undergoing mastectomy +/- immediate breast reconstruction

Where this trial is running

Cambridge, Cambridgeshire

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Breast Cancer Early Stage Breast Cancer, Breast Carcinoma, Breast Neoplasms, Breast Surgery, Breast Reconstruction Surgery, breast oncoplastic, recon, chest wall perforator flap, PROMS

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.