Partial breast reconstruction using chest wall perforator flaps
Official title: PartBreCon-Pro Study: PARTial BREast RECONstruction With Chest Wall Perforator Flap, a PROspective Study of Clinical and Patient Reported Outcomes
Run by Cambridge University Hospitals NHS Foundation Trust · NCT06728527 · Data updated 2026-11-12
This study looks at how well partial breast reconstruction using chest wall flaps works for women who have had surgery for early-stage breast cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 1001 (estimated) |
| Sponsor | Cambridge University Hospitals NHS Foundation Trust Academic / other |
| Locations | 1 site (Cambridge, Cambridgeshire) |
| Status | Recruiting |
| Started | June 1, 2023 |
| Main results expected | May 31, 2026 |
| Study ends | May 31, 2026 |
| Registry record updated | December 11, 2024 |
| Trial ID | NCT06728527 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients undergoing partial breast reconstruction for primary breast cancer who have previously undergone breast conservation surgery.
✕Probably not a fit
Patients who are undergoing volume displacement breast conservation surgery or mastectomy with or without immediate reconstruction may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the outcomes of partial breast reconstruction utilizing chest wall perforator flaps following breast conservation surgery for early-stage breast cancer. It will collect data on patient demographics, tumor characteristics, and treatment details, including surgical and oncological interventions. The study focuses on understanding how these factors influence surgical planning and patient outcomes.
Why it matters
Potential benefit: If successful, this approach could improve aesthetic outcomes and patient satisfaction after breast conservation surgery.
How similar studies have gone: Other studies have explored similar surgical techniques, indicating potential for positive outcomes, but this specific approach may offer novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing partial breast reconstruction using CWPF for primary breast cancer * Delayed correction of breast deformity following previous BCS * Each surgeon is to have performed a minimum of 10 CWPFs * Each centre anticipates completing a minimum of 10/year Exclusion Criteria: * Patients undergoing volume displacement BCS * Patients undergoing mastectomy +/- immediate breast reconstruction
Where it's running
-
Cambridge University Hospitals NHS Trust
Cambridge, Cambridgeshire, United Kingdom Recruiting
Study contacts
- Principal investigator: Amit Agrawal — Cambridge University Hospitals NHS Foundation Trust
- Study coordinator: Amit Agrawal, DM, FRCS
- Email: amit.agrawal2@nhs.net
- Phone: +44 1223 216315
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.