Condition

Ovarian Carcinoma clinical trials and research

• 36Clinical trials
• 7NIH research projects
• 18Countries

Newest Ovarian Carcinoma clinical trials

All recruiting trials (36)

• Blended e-Health Program to Help Women with Breast or Gynecologic Cancer Manage Fear of Cancer Progression

  This trial tests a blended online and group program to see if it helps women with breast or gynecologic cancer feel less fear that their cancer could grow or spread.

  Recruiting at 11 sites City of Hope Medical Center · Arcadia, California and 10 other locations · NCT07741968

• IGFBP-2 vaccine after platinum to slow ovarian cancer recurrence

  This study tests whether giving an IGFBP-2 vaccine after one carboplatin dose can help prevent progression of ovarian, fallopian tube, or primary peritoneal cancer that has shown serologic recurrence.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT07495124

• In-home cancer treatment with remote specialist support for patients in the Florida Panhandle

  This program will try giving standard cancer treatments at home to people living in the Florida Panhandle and nearby areas to see if they prefer it and have better treatment satisfaction.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT07285044

• Adapted HOPE workshop to reduce burnout for gynecologic oncology clinicians

  This program will test whether an adapted HOPE workshop can help gynecologic oncology clinicians reduce stress and burnout.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07282158

• Using ultrasound microvessel imaging to evaluate ovarian and adnexal lesions

  This test tries to see if ultrasound microvessel imaging can better detect small blood vessels in adults scheduled for surgery for ovarian or adnexal lesions.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07280312

• Sequential CD146 and GPC3 CAR-T therapy for advanced ovarian cancer

  This trial will try two sequential CAR-T cell infusions—first targeting CD146 then GPC3—in adults with advanced ovarian cancer that has returned or not responded to standard treatments.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT07067255

• Vanguard: a new blood test approach to screen for multiple cancers

  This study will test two different blood-based multi-cancer detection tests in adults 45–75 without cancer to see if they find cancers earlier than usual care.

  Recruiting at 46 sites National Cancer Institute (NCI) · Pleasanton, California and 45 other locations · NCT06995898

• DT2216 with weekly paclitaxel for platinum-resistant ovarian cancer

  We are testing whether adding DT2216 to weekly paclitaxel is safe and tolerable for people with recurrent platinum‑resistant ovarian cancer.

  Recruiting at 2 sites Phase 1 Dana-Farber Cancer Institute · Boston, Massachusetts and 2 other locations · NCT06964009

• Comparing niraparib and bevacizumab for ovarian cancer maintenance therapy

  This study is trying to see if a maintenance treatment with niraparib works better than bevacizumab for women with advanced ovarian cancer who have already had chemotherapy.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Occitanie · NCT06827353

• Using vagus nerve stimulation to improve quality of life in ovarian cancer treatment

  This study is testing if a new device that stimulates the vagus nerve can help improve the quality of life for women undergoing chemotherapy for ovarian cancer by reducing digestive problems.

  Recruiting Phase 3 Centre Francois Baclesse · Caen and 3 other locations · NCT06817161

• Using Belzutifan to treat recurrent clear cell ovarian carcinoma

  This study is testing if a new targeted therapy called Belzutifan can help people with recurrent clear cell ovarian cancer feel better and manage their disease.

  Recruiting at 2 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06677190

• Overcoming immune suppression and rebalancing the immune response in ovarian cancer

  We will try to find and reverse immune suppression by analyzing bone marrow, blood, spleen, peritoneal fluid, and tumor samples from women having surgery for ovarian cancer.

  Recruiting Gynaecologisch Oncologisch Centrum Zuid · Eindhoven, North Brabant · NCT06611072

• Evaluating NKT3964 for Adults with Advanced Solid Tumors

  This study is testing a new drug called NKT3964 to see if it can safely help adults with advanced solid tumors, like ovarian or triple-negative breast cancer, after other treatments have failed.

  Recruiting at 17 sites Phase 1 NiKang Therapeutics, Inc. · Little Rock, Arkansas and 20 other locations · NCT06586957

• Testing Olaparib with or without Bevacizumab for Ovarian Cancer Treatment

  This study is testing if a new cancer treatment called olaparib, alone or with another drug called bevacizumab, can help women with advanced ovarian cancer live longer without their cancer getting worse.

  Recruiting at 682 sites Phase 3 NRG Oncology · Birmingham, Alabama and 708 other locations · NCT06580314

• Testing a new communication tool for ovarian cancer patients and their caregivers

  This study is testing a new communication tool to see if it helps ovarian cancer patients, their caregivers, and doctors work better together in planning care.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT06543537

• Using cryocompression and cilostazol to prevent nerve damage from chemotherapy in women with gynecological cancers

  This study is testing if using cryocompression therapy alone or with a medication called cilostazol can help prevent nerve damage from chemotherapy in women with gynecological cancers.

  Recruiting Phase 2 Emory University · Atlanta, Georgia and 2 other locations · NCT06492070

• Measuring tissue oxygen levels during surgery for ovarian cancer

  This study is testing if low oxygen levels in muscle during surgery for ovarian cancer can lead to kidney problems afterward in women undergoing treatment.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT06475261

• Improving access to genetic testing for underserved cancer patients

  This study is testing whether a computer character can give better information about genetic testing to underserved cancer patients compared to regular human healthcare providers.

  Recruiting at 2 sites University of Southern California · Los Angeles, California and 1 other locations · NCT06422455

• Treatment for recurrent ovarian cancer with HER2 expression

  This study is testing a new combination of treatments for women with recurrent ovarian cancer that has a specific protein called HER2 to see if it helps them feel better and live longer.

  Recruiting Phase 2 Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT06420973

• CIML NK cell therapy for recurrent ovarian cancer

  This study is testing a new treatment using special immune cells to see if it can help people with recurrent high-grade ovarian cancer feel better and improve their health.

  Recruiting Phase 1 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06321484

• Investigating blood cancer risks in patients with ovarian and other solid tumors

  This study is trying to see if certain cancer treatments for ovarian and other solid tumors can increase the risk of blood cancers in patients.

  Recruiting University of Washington · Seattle, Washington · NCT06295965

• Using blood volume management during surgery for ovarian cancer patients

  This study tests if a blood management technique called acute normovolemic hemodilution can help women with advanced ovarian cancer during surgery by reducing the need for blood transfusions and improving safety.

  Recruiting at 7 sites Phase 2 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT06290193

• Investigating HER3-DXd for advanced solid tumors

  This study is testing a new drug called HER3-DXd to see if it can safely help people with advanced solid tumors like melanoma, head and neck cancer, and gastric cancer who have already tried other treatments.

  Recruiting at 92 sites Phase 2 Daiichi Sankyo · Duarte, California and 95 other locations · NCT06172478

• Evaluating sentinel lymph node biopsy for early-stage ovarian cancer

  This study is testing if a new type of lymph node surgery can help women with early-stage ovarian cancer get better treatment while reducing the risks of more extensive surgery.

  Recruiting Istanbul University · Istanbul, Turkey · NCT05927818

• Dendritic cell vaccination for ovarian cancer treatment

  This study is testing a special vaccine made from immune cells to see if it can help women with advanced ovarian cancer feel better while they receive chemotherapy.

  Recruiting Phase 1/2 Radboud University Medical Center · Nijmegen, Gelderland · NCT05773859

• Comparing stress reduction methods to standard care for ovarian cancer patients

  This study is testing if a mix of medications and therapies can help reduce stress in women with advanced ovarian cancer before their surgery, compared to those getting standard care.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT05429970

• Exercise program to help cancer patients during chemotherapy

  This study tests if a 16-week online exercise program can help women with ovarian or endometrial cancer feel better during their first round of chemotherapy.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT04997096

• Analyzing solid tumors for HLA loss and collecting T cells for CAR T-cell therapy

  This study is testing how often solid tumors lose a key protein that helps the immune system recognize them, while also collecting T cells from patients with high-risk cancers to prepare for future CAR T-cell therapy.

  Recruiting at 13 sites A2 Biotherapeutics Inc. · Gilbert, Arizona and 15 other locations · NCT04981119

• Tegavivint treatment for recurrent or refractory solid tumors in children

  This study tests if a new intravenous medication called tegavivint can help children with tough-to-treat solid tumors, like Ewing sarcoma and desmoid tumors, by finding the right dose and seeing how well it works.

  Recruiting at 19 sites Phase 1/2 Children's Oncology Group · Birmingham, Alabama and 20 other locations · NCT04851119

• First-in-human use of JAB-8263 in adults with advanced solid and blood cancers

  This trial will try JAB-8263, a BET inhibitor pill, in adults with advanced solid tumors or blood cancers that have progressed after standard treatments.

  Recruiting Phase 1/2 Jacobio Pharmaceuticals Co., Ltd. · Tianjin, Tianjin Municipality · NCT04686682

• Understanding immune changes in breast and ovarian cancer patients

  This study looks at how the immune system changes in women with breast and ovarian cancer to find ways to make treatments work better.

  Recruiting Centre Leon Berard · Lyon, France · NCT04562623

• Comparing two surgical procedures to lower ovarian cancer risk in women with BRCA1 mutations

  This study is testing if a less invasive surgery can lower the risk of ovarian cancer just as well as a more extensive surgery for women with BRCA1 mutations.

  Recruiting at 548 sites NRG Oncology · Birmingham, Alabama and 629 other locations · NCT04251052

• Imaging with a new radioactive tracer for solid tumors

  This study is testing a new imaging method using a special radioactive tracer to see if it can help find tumor cells in patients with solid tumors like ovarian and breast cancers, while also looking at how safe it is and how it relates to certain genetic factors.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT03604315

• Study of women with BRCA1 or BRCA2 gene variants and cancer risk

  This study looks at Japanese women with BRCA1 or BRCA2 gene changes to see how likely they are to develop certain cancers and whether a specific surgery can help prevent them.

  Recruiting Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan · Okayama · NCT03296826

• Identifying biomarkers and treatment strategies for peritoneal surface malignancies

  This study is trying to find specific markers in patients with peritoneal surface cancers to help choose the best treatment options and improve their chances of recovery.

  Recruiting Oslo University Hospital · Oslo · NCT02073500

• Collecting data on patients with low-grade ovarian or peritoneal tumors

  This study is collecting information from around 1600 women with low-grade ovarian or peritoneal tumors to help understand their disease and improve future treatments.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT00488878

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Using imaging data to predict outcomes in ovarian cancer patients

  This study is looking at how regular CT scans can be used to find important clues that help predict how well women with a specific type of ovarian cancer might do after treatment, so doctors can make better choices for their care.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11172693

• Hippo/YAP pathway in aggressive ovarian cancer

  Researchers aim to find out how a cell-control system called Hippo/YAP helps start and drive the most deadly form of ovarian cancer in women.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11144436

• Blocking CDK7 as a new approach for aggressive ovarian cancer

  This work explores whether blocking a protein called CDK7 can help treat women with high-grade serous ovarian cancer, especially tumors with CDK7 loss or BRCA-related DNA repair problems.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11131193

• New methods to treat a specific type of ovarian cancer

  This study is looking at a tough type of ovarian cancer called high-grade serous tubo-ovarian carcinoma to find out why it often doesn't respond to regular treatments, and it's testing new therapy combinations to help improve outcomes for patients like you.

  NIH research New York University School of Medicine · New York, United States · NIH-11001564

• A new CAR T cell therapy targeting ovarian cancer

  This study is testing a new type of CAR T cell therapy for women with ovarian cancer that uses special immune cells to better target the cancer and includes a safety feature to help protect patients from side effects.

  NIH research Luminary Therapeutics, INC. · Minneapolis, United States · NIH-10921643

• Combining trametinib and navitoclax to treat recurrent ovarian cancer

  This study is testing a new combination treatment for women with recurrent ovarian cancer that hasn't responded to standard therapies, aiming to see if it can help improve their outcomes.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-10895326

• Targeting a specific protein to treat advanced ovarian cancer

  This study is looking at a new way to help people with advanced ovarian cancer by targeting a specific protein that helps cancer cells survive, hoping to make current treatments work better for those who have few options left.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10894152

Related topics

Quick answers

How many Ovarian Carcinoma clinical trials are recruiting right now?

36, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in United States (24 trials), China (4 trials), France (4 trials), South Korea (3 trials), Netherlands (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 1/2: 4, Phase 1: 4, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →