Comparing synthetic mammography to full-field digital mammography for breast cancer detection
Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics
This study is testing if synthetic mammography can find breast cancer better and with fewer follow-up appointments than traditional digital mammography.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 750 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT05056818 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effectiveness of synthetic mammography in comparison to full-field digital mammography in interpreting breast images and assessing performance metrics. It leverages data from patients' medical records and past imaging examinations to analyze the characteristics and utility of synthetic mammography, which is a 2D image reconstructed from digital breast tomosynthesis data without additional radiation. The study aims to provide insights into how synthetic mammography may improve breast cancer detection rates and reduce recall rates compared to traditional methods.
Who should consider this trial
Good fit: Ideal candidates for this study are females aged 18 or older who have undergone breast imaging at the participating center.
Not a fit: Patients with administrative or technical errors in their imaging records will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved breast cancer detection and reduced unnecessary follow-up procedures for patients.
How similar studies have performed: Previous studies have indicated that digital breast tomosynthesis is superior to standard digital mammography, suggesting that this comparative approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female * Age 18 or older * Consecutive cases in breast imaging center Exclusion Criteria: * Cases demonstrate administrative or technical errors (e.g. missing views, labeling inconsistent with report, etc.)
Where this trial is running
Houston, Texas
- M D Anderson Cancer Center — Houston, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Ray C Mayo — M.D. Anderson Cancer Center
- Study coordinator: Ray C Mayo, MD
- Email: rcmayo@mdanderson.org
- Phone: 713-745-4555
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.