Condition

Autism clinical trials and research

• 81Clinical trials
• 477NIH research projects
• 1New in 30 days
• 16Countries

Newest Autism clinical trials

All recruiting trials (81)

• Interactive massage for toddlers with autism

  A mom-led 3-month interactive massage program is being tested to see if it improves parent-child interaction in toddlers with autism, compared with usual care.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT07876245

• Share or Not to Share: A Peer-Led Support Program for Caregivers of Autistic Young Adults

  A group, peer-led program tests how six virtual sessions can support family caregivers of autistic young adults (ages 18–26) in navigating roles, sharing experiences, and planning for the future.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07856927

• Behavioral Activation for Depression in Autistic Teens with Below-Average IQ

  This study tests a tailored behavioral activation approach to see if it helps reduce depressive symptoms in autistic adolescents who have below-average cognitive abilities.

  Recruiting Stony Brook University · Stony Brook, New York · NCT07812870

• Museum visits to support social and emotional well‑being in autistic adults

  This study tests whether visiting the National Taiwan Museum can help improve social participation and well-being for autistic adults aged 18–50.

  Recruiting National Taiwan University Hospital · Taipei · NCT07768332

• Parent-Mediated Social-Cognition Intervention for Young Children with Autism

  This study tests a parent-led, home-based play program to help young children with autism improve social-cognition skills.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT07708246

• A guided self-help workbook to boost autistic wellbeing

  This study tests a short guided self-help workbook for autistic adults in UK mental health services to see if it is acceptable and may improve wellbeing.

  Recruiting Canterbury Christ Church University · Maidstone · NCT07630376

• Regulating Together for Emotion Dysregulation in ASD and Intellectual Disability (group therapy)

  This study tests a group therapy program for kids with autism and co-occurring intellectual disability to help them manage irritability and aggression, with sessions for both children and their caregivers.

  Recruiting Children's Mercy Hospital Kansas City · Kansas City, Missouri · NCT07624448

• AdiaVita and glutathione for autism in kids and teens

  This study tests whether adding AdiaVita (cord-blood stem cells and exosomes) to glutathione helps improve ASD symptoms in children and other participants compared with glutathione alone.

  Recruiting at 2 sites Phase 1 Greater Atlanta Integrative Pediatrics · Roswell, Georgia and 1 other locations · NCT07622316

• Online test of BlinkLab Dx1 for autism in kids aged 2–11

  This study tests whether the BlinkLab Dx1 smartphone app can help identify autism in children aged 2 to 11 by comparing app-based measurements with prior clinical diagnoses.

  Recruiting Blinklab Limited · Princeton, New Jersey · NCT07590973

• Project Independence: a quick online tool to help caregivers support autistic youth

  A brief online session helps parents and other caregivers boost daily independence for autistic youths aged 10–14 by trying a single-session program versus watching a neutral video.

  Recruiting University of Miami · Coral Gables, Florida · NCT07572110

• Toolkit to help therapists treat autistic teens with mental health needs

  A pilot study will test a therapist-facing toolkit designed to improve how mental health care is provided to autistic teens.

  Recruiting Florida International University · Miami, Florida and 1 other locations · NCT07539519

• Digital conversational companion for autistic young adults

  This project will try a mobile conversational agent as a digital companion to help autistic young adults set and reach personal goals and support mental health.

  Recruiting at 3 sites Friendi.fi Corporation · Bloomington, Indiana and 2 other locations · NCT07533331

• Five Digits Test: a quick inhibition test for adults with ADHD or autism

  This project will test whether the Five Digits Test is a quick, language-light way to measure inhibition in adults with ADHD or autism.

  Recruiting Umeå University · Umeå · NCT07531914

• Family and Friend Support for Early Intervention in Autism

  This study tests whether the FANS-EI program helps caregivers stay engaged in early intervention for young children with autism.

  Recruiting University of California, Davis · Sacramento, California · NCT07500363

• Rest, emotion, and arousal in autistic children ages 6–10

  This study tests whether a caregiver-delivered "Power Down" bedtime massage can lower bedtime arousal and help sleep and daytime emotion regulation in autistic children ages 6–10 with sensory over-responsivity.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07476937

• Family-centered parent training for autistic toddlers in early intervention

  A parent training program focused on helping families of toddlers with autism try strategies to improve their child’s emotion regulation within existing home-based early intervention services.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT07471594

• Gut barrier and gut microbes in children with autism

  This trial will test whether a one-month course of postbiotic supplements can improve gut symptoms and behavior in children with autism aged 3–8.

  Recruiting at 2 sites Phase 2/3 Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Milan, MI and 1 other locations · NCT07450443

• Trauma‑Focused Cognitive Behavioral Therapy adapted for autistic children and teens (pilot implementation)

  This pilot will try TF‑CBT adapted for autistic children and teens with trauma-related symptoms to see if community mental health clinicians can deliver it and families find it acceptable.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07420478

• CRUSH curriculum for romance and sexual health for autistic young adults

  This project will try the CRUSH program—a group course plus one-to-one coaching—to teach sexual health and dating skills to autistic adults ages 18 to 30.

  Recruiting Boston Children's Hospital · Brookline, Massachusetts · NCT07406100

• Static balance testing in children with autism using a virtual reality system

  This project tests whether a virtual reality rehabilitation system can measure static balance differences in children with autism aged 6–10.

  Recruiting Istituto per la Ricerca e l'Innovazione Biomedica · Messina · NCT07403396

• Virtual reality to improve emotion understanding in children with autism

  This project will test whether an Oculus virtual-reality program helps children with autism better recognize and understand emotions compared with a traditional intervention.

  Recruiting Istituto per la Ricerca e l'Innovazione Biomedica · Messina, Italy · NCT07367256

• Emotional intelligence and accommodation training for autistic adults and their learning partners

  This project will try Kairon's online emotional intelligence/leadership training for autistic adults (ages 18–36) together with autism accommodation training for a non-autistic learning partner to see if the trainings help each person and their relationship.

  Recruiting Kairon Connect, PBC · Wexford, Pennsylvania · NCT07315867

• Do AdiaVita stem cells plus glutathione help kids with autism more than glutathione alone?

  This 12-month study tests whether adding AdiaVita stem cells and exosomes to glutathione helps children aged 3–12 with autism more than glutathione alone.

  Recruiting at 2 sites Phase 1 Adia Med of Winter Park LLC · Winter Park, Florida and 1 other locations · NCT07304440

• Combined training to improve thinking skills and emotional control for children with ADHD, dyslexia, or autism

  This program will test whether a combined training that targets both 'cool' thinking skills (like working memory) and 'hot' emotion-related control can help primary-school children aged 6–11 with ADHD, dyslexia (SpLD), or autism.

  Recruiting Education University of Hong Kong · Tai Po · NCT07262853

• Guided breathing to improve stress and heart rate variability in autistic young adults

  This study will test two guided breathing exercises to see if they reduce stress and improve heart rate variability in autistic people aged 16–25.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams Brabant and 1 other locations · NCT07238153

• Remote problem-solving program for autistic teens and their caregiver

  This project will test a remote problem‑solving program (PREP) for autistic adolescents and young adults ages 13–21 together with a primary caregiver to help with independence and transition skills.

  Recruiting University of Missouri-Columbia · Columbia, Missouri · NCT07216196

• Nature- and activity-based group programs for neurodivergent children and youth in Agder

  This project will try outdoor and activity-based group programs to see if they help children and teens with ADHD, autism, Tourette's, and related neurodivergent challenges feel better, gain confidence, and do better in daily life.

  Recruiting at 2 sites Sorlandet Hospital HF · Kristiansand, Agder and 1 other locations · NCT07203469

• Terpenes‑enriched CBD oil with a very small THC dose for children with autism

  This trial will test whether a terpene‑enriched CBD oil with a very small amount of THC can reduce behavioral problems and improve social functioning in children ages 4–12 with autism.

  Recruiting Phase 2 Bazelet Nehushtan LtD. · Jerusalem, N/A = Not Applicable · NCT07199218

• Improving early intervention for toddlers with communication delays in Georgia

  This project will try two ways of training Georgia Early Intervention providers in Project ImPACT to see which approach helps families of children under 3 with autism-related communication delays get better support.

  Recruiting Emory University · Atlanta, Georgia · NCT07148258

• Optimizing rewards to support learning in people with intellectual and developmental disabilities

  This project will test different timings and amounts of small rewards to see if they help people with intellectual and developmental disabilities learn simple tasks and stay motivated.

  Recruiting at 3 sites Auburn University · Auburn, Alabama and 2 other locations · NCT07137273

• Speech and language outcomes after neonatal hypoxic-ischemic encephalopathy

  We will see if early newborn tests—blood gas and lactate values, aEEG, and MRI (especially corpus callosum ADC)—can predict language, IQ, memory, or later diagnoses like autism and ADHD in children aged 4–7 who had moderate to severe HIE and therapeutic hypothermia.

  Recruiting Semmelweis University · Budapest · NCT07136636

• VR motor training to improve strength, balance, and control in adults with autism

  This trial tests whether a 6-week virtual reality motor training program can improve muscle strength, balance, and motor control in adults with autism compared with non-autistic controls.

  Recruiting National Taiwan University Hospital · Taipei · NCT07134569

• Spanish-language Unstuck and On Target program for children with autism or ADHD

  This program will test whether a Spanish-language version of Unstuck and On Target helps Spanish-speaking caregivers and their 8–11-year-old children with autism and/or ADHD improve executive skills and reduce caregiver strain.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT07084324

• Opt-In early intervention program for young children waiting for an autism diagnosis.

  This program tests an online parent-training course to help toddlers (16–48 months) showing signs of autism whose families are on a waitlist for a formal diagnosis.

  Recruiting Drexel University · Philadelphia, Pennsylvania · NCT07081724

• Footsteps app to improve behavioral data collection, supervision, and student outcomes

  This test will see if a smartphone app called Footsteps helps school aides collect better behavior data and improves outcomes for students aged 3–17 who receive one-to-one support.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07042347

• Prednisone in adults with an immune-related subtype of autism

  This study tests whether prednisone, an anti-inflammatory drug, can help adults with a specific immune-related form of autism compared to a placebo.

  Recruiting Early Phase 1 Massachusetts General Hospital · Lexington, Massachusetts · NCT06934915

• Examining how sensory integration affects attention in autism

  This study is testing how different ways of presenting sounds and visuals affect attention in people with autism compared to those without autism.

  Recruiting Istituto per la Ricerca e l'Innovazione Biomedica · Messina, ME · NCT06872229

• A program to improve social skills in adults with autism

  This study is trying out a new program called TUNE In to see if it can help adults with autism improve their social skills and feel more comfortable in everyday situations.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT06859918

• Adderall XR for attention problems in children and teens with autism

  This 10-week study will test whether Adderall XR (mixed amphetamine salts) helps reduce ADHD symptoms and changes brain activity in children and adolescents (ages 8–18) who have autism.

  Recruiting Phase 4 Massachusetts General Hospital · Boston, Massachusetts · NCT06853665

• Exploring how early life experiences affect brain and behavior

  This study looks at how early life experiences like adoption and trauma affect brain development and behavior in young adults to help identify those at risk for mental health issues later on.

  Recruiting University of Manchester · Manchester · NCT06823492

• Culturally adapted Pathways to support social and language skills in young Hispanic autistic children

  This project tests whether adding a 'mutual gaze' technique to a culturally adapted parent-led Pathways program helps social communication, language, and everyday skills in Hispanic autistic children aged 18–42 months from low-income families.

  Recruiting at 2 sites The University of Texas at Dallas · Lawrence, Kansas and 2 other locations · NCT06733584

• Improving social and academic skills in middle-schoolers with autism

  This study tests two different group programs to see if they can help middle-school kids with autism improve their social and school skills.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06705907

• Assessing autism outcomes in children born to mothers with HIV in Kenya

  This study is testing if eye movement patterns in young children exposed to HIV can help identify signs of autism.

  Recruiting Indiana University · Eldoret · NCT06703125

• Using magnetoencephalography to diagnose brain disorders in children

  This study is testing if a special brain imaging technique called magnetoencephalography can help doctors better diagnose brain disorders in children, like epilepsy and autism.

  Recruiting Children's Hospital of Fudan University · Shanghai · NCT06668519

• Learning words through parentese in autistic children

  This study is testing if using a special way of talking called parentese helps autistic children learn new words better when it's done through videos compared to live interactions.

  Recruiting The University of Texas at Dallas · Richardson, Texas · NCT06649916

• Sleep therapy for children with autism and sleep issues

  This study is testing a new sleep therapy delivered online to see if it can help children with autism who have trouble sleeping.

  Recruiting Stanford University · Stanford, California · NCT06627205

• Online Pivotal Response Treatment training for parents of young children with autism

  This program will test whether an online Pivotal Response Treatment course can teach English-speaking parents to deliver PRT effectively to children with autism ages 2 to 5.

  Recruiting Stanford University · Stanford, California · NCT06523387

• Parent-led intervention for autistic children with insistence on sameness

  This study tests if a virtual program for parents can help children with autism, aged 6 to 10, reduce their need for things to be the same all the time.

  Recruiting Stanford University · Stanford, California · NCT06472115

• Using eye tracking to detect autism risk in young children

  This study is testing if a special eye-tracking device can help find signs of autism risk in young children aged 12 to 48 months.

  Recruiting Indiana University · Indianapolis, Indiana · NCT06471504

• Behavioral intervention for rigidity in autistic youth

  This study is trying out a 12-week program that helps parents support their autistic kids, aged 4 to 17, in being more flexible and open to change.

  Recruiting Stanford University · Stanford, California · NCT06362733

• Improving transition outcomes for students with autism

  This study is testing a new program to help autistic students set and achieve their goals as they transition from high school to adulthood, with support for them and their families.

  Recruiting Ball State University · Muncie, Indiana · NCT06309160

• Using stem cells from Wharton jelly to treat autism

  This study is testing if stem cells from Wharton jelly can help children with autism improve their social skills and behavior.

  Recruiting Phase 1 University of Jordan · Amman · NCT06293950

• A program to help young adults with autism maintain their jobs by focusing on their strengths

  This study tests a new program that helps young adults with autism keep their jobs by focusing on their strengths and teaching them how to showcase those strengths to employers.

  Recruiting Kessler Foundation · East Hanover, New Jersey · NCT06255925

• Testing Vitamin B6 for sensory reactivity in autism

  This study is testing if high doses of Vitamin B6 can help autistic adults feel less anxious and sensitive to sensory input.

  Recruiting University of Reading · Reading · NCT06234501

• Improving toothbrushing skills in teens with autism using a mobile app

  This study is testing a new version of a toothbrushing app designed for teens with autism to see if it helps them brush their teeth better and prevent cavities.

  Recruiting University of Washington · Seattle, Washington · NCT06208722

• Supplementation therapy for anxiety and depression in autistic individuals

  This study is testing if a supplement called PEA can help reduce anxiety and depression in young adults with Level 1 Autism Spectrum Disorder who haven't found relief with other treatments.

  Recruiting University of Udine · Udine, UD · NCT06187090

• Comparing Sertraline and Placebo for Treating Anxiety in Children with Neurodevelopmental Disorders

  This study is testing if the medication sertraline can help reduce anxiety in children and teens aged 8-17 with neurodevelopmental disorders like autism and Fragile X syndrome compared to a placebo.

  Recruiting at 6 sites Phase 2 Holland Bloorview Kids Rehabilitation Hospital · Calgary, Alberta and 6 other locations · NCT06081348

• Evaluating improvisational music therapy for autistic children

  This study is testing if adding improvisational music therapy to regular care can help improve social communication skills in children with autism aged 7 to 11.

  Recruiting at 2 sites University of Cambridge · Cambridge and 1 other locations · NCT06016621

• Evaluating the Early Start Denver Model for young children with autism in community settings

  This study is testing if the Early Start Denver Model can improve autism care for young children in community settings.

  Recruiting University of California, Davis · Sacramento, California · NCT06005285

• Screening infants for autism using eye-tracking technology

  This study is testing whether an eye-tracking device can help spot signs of autism and developmental delays in 9-month-old babies during their regular check-ups.

  Recruiting at 2 sites Emory University · Atlanta, Georgia and 1 other locations · NCT05916430

• Training toddlers with autism to improve imitation and rhythm sensitivity

  This study is testing if adding music to a training program helps toddlers with autism learn to imitate better and if their ability to respond to rhythms affects how well they do.

  Recruiting Vanderbilt University Medical Center · Nashville, Tennessee · NCT05880225

• Validation of the SenseToKnow app for autism screening in young children

  This study is testing a new app called SenseToKnow to see if it can help parents identify autism in their toddlers aged 16 to 36 months compared to expert diagnoses.

  Recruiting Duke University · Durham, North Carolina · NCT05874466

• Using prescribed physical activity to improve health in people with disabilities

  This study is testing whether a program that prescribes specific physical activities can help children and young people with disabilities, like autism and intellectual disabilities, improve their health and be more active.

  Recruiting Region Skane · Malmö · NCT05867940

• Understanding sensory characteristics in autism spectrum disorder

  This study is trying to understand how people with autism experience their senses and how these sensory experiences affect their social interactions as they grow older.

  Recruiting National Taiwan University Hospital · Taipei · NCT05829161

• Virtual magic trick training for adolescents with autism

  This study is testing whether a virtual magic trick training program can help teenagers with autism improve their social skills and reduce stress.

  Recruiting Phase 2 University of Alabama at Birmingham · Birmingham, Alabama · NCT05664841

• Using suvorexant to improve sleep in children with autism

  This study is testing if a sleep medication called suvorexant can help children and teens with autism sleep better.

  Recruiting Phase 2 Stanford University · Stanford, California · NCT05546554

• Using zolpidem to improve sleep in children with autism

  This study is testing if a sleep medication called zolpidem can help improve sleep quality in children and teens with autism who have trouble sleeping.

  Recruiting Phase 2 Stanford University · Stanford, California · NCT05540574

• Using diphenhydramine to improve sleep in children with autism

  This study is testing if diphenhydramine can help improve sleep for children and teens with autism.

  Recruiting Phase 2 Stanford University · Stanford, California · NCT05501678

• A new approach to diagnosing autism in young children

  This study is testing a new way to diagnose autism in toddlers who are at high risk to see if it can make the process quicker and easier for families.

  Recruiting Emory University · Atlanta, Georgia · NCT05419895

• Impact of cerebellum neuromodulation on social and executive functions in autism

  This study is testing how a brain stimulation technique affects social skills and thinking abilities in young adults with autism and those without it.

  Recruiting American University · Washington D.C., District of Columbia · NCT05396352

• Infusion of stem cells for treating autism

  This study is testing whether an infusion of stem cells from umbilical cords can help improve symptoms in people with autism.

  Recruiting at 2 sites Phase 1 The Foundation for Orthopaedics and Regenerative Medicine · Naples, Florida and 1 other locations · NCT05003960

• Comparing center-based and home-based treatment for young children with autism

  This study tests whether treatment for young children with autism works better when done at a center or at home, focusing on improving their language and social skills.

  Recruiting Stanford University · Stanford, California · NCT04899544

• Using Bumetanide to Treat Autism in Children

  This study is testing if Bumetanide can help reduce autism symptoms in children aged 3 to 12 years.

  Recruiting Phase 3 Tanta University · Tanta · NCT04766177

• Using Transcranial Magnetic Stimulation to Treat Repetitive Behaviors in Autism

  This study is testing if a non-invasive brain treatment can help reduce repetitive behaviors in people with Autism Spectrum Disorder who haven't had success with other treatments.

  Recruiting Stanford University · Stanford, California · NCT04532424

• Using sensors to help non-verbal individuals communicate their needs

  This study is trying to see if using heart rate and breathing monitors can help non-verbal individuals with intellectual disabilities, autism, or cerebral palsy communicate their needs better.

  Recruiting University of Oslo · Oslo · NCT04199299

• Specialized employment program for adults with autism

  This study tests whether a specialized job support program can help adults with autism keep their jobs and improve their quality of life compared to those who start the program later.

  Recruiting Stanford University · Palo Alto, California · NCT04107064

• Using fecal microbiota transplantation to treat gut disorders

  This study is testing whether a treatment that involves using healthy stool to help restore gut bacteria can improve symptoms for people with gut disorders like Crohn's disease and irritable bowel syndrome.

  Recruiting Chinese University of Hong Kong · Hong Kong, Shatin · NCT04014413

• Esomeprazole for social communication problems in young children with autism

  This 12-week open-label study will try esomeprazole in children ages 2–6 with autism to see if it improves social communication.

  Recruiting Phase 2 Stanford University · Stanford, California · NCT03866668

• Identifying brain markers for treatment response in young children with autism

  This study is testing if brain scans can help predict how young children with autism will respond to a specific therapy to improve their behavior and communication skills.

  Recruiting Stanford University · Stanford, California · NCT03583684

• Intensive therapy for children with neuromotor impairments

  This study tests whether a special therapy can help children with movement difficulties improve their motor skills by focusing more on their weaker side.

  Recruiting Virginia Polytechnic Institute and State University · Roanoke, Virginia · NCT03325946

• Screening protocol for evaluating neurodevelopmental and behavioral conditions

  This study is testing a new way to check for neurodevelopmental and behavioral conditions in healthy volunteers and those at risk, like autism, to see if they can join future research at the National Institute of Mental Health.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00271622

NIH-funded research (newest 40 of 477)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Neural roots of how autistic adults understand word meaning

  A study to understand how adults with autism process word meanings in the brain, aiming to improve language support.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11640092

• Sleep and daily rhythms and brain development in autism

  Aiming to understand how sleep problems and daily activity patterns affect brain growth, thinking skills, daily functioning, and autism symptoms in children.

  NIH research Hugo W. Moser Res Inst Kennedy Krieger · Baltimore, United States · NIH-11597098

• Early sensory development and language in infants/toddlers at risk for autism

  A family-friendly study exploring how early sensory responses relate to language development in young children who have siblings with autism.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11594304

• Autism Caregiver Coaching in Africa for Young Children

  A Duke University-led project in South Africa aims to help young children with autism by training caregivers to deliver proven coaching strategies through non-specialist providers.

  NIH research Duke University · Durham, United States · NIH-11580298

• Autism and Self-regulation: Remote Testing of Heart-Related Signals in Kids

  A study to see if remote testing can safely measure how children with autism and disruptive behavior manage emotions and self-control by tracking heart signals and other markers.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11540693

• Understanding brain signals in autism to identify biologically distinct subtypes

  This study uses EEG to link how the brain processes sensory information with behavior in young children with autism and related concerns.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11532027

• Paternal exposures and sperm epigenetics linked to autism in children

  This project looks at how a father's environment and health before conception might influence autism risk in his children.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11520495

• Long-Term Brain and Behavior Study of Autism from Infancy through Adolescence

  This NIH project follows children at risk for autism from infancy into adolescence to understand how brain and behavior evolve over time.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11478433

• Longitudinal brain and behavior study of autism from infancy through adolescence

  A long-term study follows people at risk for autism from infancy into adolescence to understand how brain changes relate to autism over time.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11478411

• Autism outcomes and neurobehavioral markers in HIV-exposed but uninfected children in Kenya

  This project follows young children who were exposed to HIV but not infected to understand autism risk and find simple, scalable ways to detect it early.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11474072

• Anxiety Management for Young Children with Autism

  A study at a major hospital will test a medication called buspirone in young children with autism to see if it helps reduce anxiety.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11471997

• Understanding how kids with autism talk and stay motivated across ages and people

  A long-term study following autistic and non-autistic kids from late childhood into early adolescence to see how social communication and motivation change over time.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11465716

• Understanding Alcohol Use in Teens and Young Adults with Autism

  A study following autistic teens and young adults to understand how and when alcohol use starts and grows over time.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11448911

• CNTNAP2: How a nerve protein may help ovarian cancer spread in the abdomen

  A small NIH grant is studying whether a protein involved in nerves, CNTNAP2, helps ovarian cancer cells stick and spread in the abdomen.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11437637

• Autism-Linked Maternal Autoantibodies and Brain-Behavior Outcomes

  This grant explores how certain antibodies from a mother during pregnancy may influence autism-related brain development and behavior in children.

  NIH research University of California at Davis · Davis, United States · NIH-11433976

• Autism screening tool using health data for 18-month-olds

  A Duke-led project uses health data from routine medical care to create an automatic tool that helps doctors screen babies around 18 months for autism and guide referrals.

  NIH research Duke University · Durham, United States · NIH-11419290

• Digital health tools to spot autism early and monitor it over time

  A smartphone/tablet app uses computer vision and machine learning to help parents identify early signs of autism in toddlers and track their development over time.

  NIH research Duke University · Durham, United States · NIH-11419288

• Duke Autism Center of Excellence: digital health and biomarkers for early autism screening and tracking

  A Duke program is building digital tools to screen for autism early, track outcomes, and discover biomarkers to guide clinical trials for young children.

  NIH research Duke University · Durham, United States · NIH-11419214

• Coaching and Leadership in Autism Support Settings (CLASS) for schools

  A school-based program will be tested to help educators better manage behaviors in autistic children, and to see if a structured leadership support approach helps sustain effective practices.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11418367

• Autism Biomarkers for Earlier ADHD… wait no: Autism Center of Excellence Network: Neurodevelopmental Biomarkers of Late Diagnosis in Autism

  Aims to help people aged 16–30 who may have autism but were diagnosed late or not at all by using AI to find early warning signals and create a practical screening tool.

  NIH research University of Virginia · Charlottesville, United States · NIH-11415604

• Developmental paths in infants at genetic risk for autism

  This grant studies whether early genetic risk and developmental patterns can point to autism earlier in infants so they can get help sooner.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11413757

• Psychosocial effects of newborn autism genetic risk on families

  This grant tests how telling parents that their newborn has a genetic risk for autism affects their feelings, relationships, and plans over the first two years.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11413754

• Predicting autism risk in newborns using genetics

  A newborns’ genes are studied to identify those who might be at higher risk for autism so that families and clinicians can plan early support.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11413750

• Genetic risk screening for autism in newborns and early life follow-up

  This project tests how early genetic information from newborns can help identify kids at higher autism risk and guide timely care.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11413709

• Early autism screening in primary care to help kids get diagnosed sooner

  This grant tests how to reliably screen for autism during routine pediatric check-ups to help children get diagnosed earlier and access intervention sooner.

  NIH research Drexel University · Philadelphia, United States · NIH-11412959

• PHASES: public health steps to support autism across the life span

  Aimed at improving autism detection, health care, and overall well‑being from early childhood through older adulthood, by using public health strategies to reach more people and better services.

  NIH research Drexel University · Philadelphia, United States · NIH-11412945

• Pharmacological Probing of Sleep in Children with Autism

  This project investigates how a sleep-related drug affects sleep patterns and daytime behavior in kids with autism.

  NIH research Stanford University · Stanford, United States · NIH-11408808

• Sleep problems in autism and daily functioning

  A large study at a major university is looking at how sleep problems affect children with autism and their daily lives.

  NIH research Stanford University · Stanford, United States · NIH-11408805

• Sleep and ASD: Understanding how sleep problems relate to autism symptoms

  A Stanford team is studying whether sleep problems contribute to and worsen autism symptoms in children and how improving sleep could help.

  NIH research Stanford University · Stanford, United States · NIH-11408795

• Understanding how autism risk genes affect brain development using zebrafish

  Researchers are testing how autism risk genes influence brain development by studying them in zebrafish and human stem cells to uncover shared harmful pathways.

  NIH research Yale University · New Haven, United States · NIH-11408569

• Learning platform to help minimally verbal children with autism communicate

  A new iOS-based platform called Young Speaker aims to help children with autism who are minimally verbal by making personalized AAC practice and video modeling materials quickly.

  NIH research Young Tech Solutions LLC · Brookfield, United States · NIH-11407400

• Family genetics linking autism and fragile X syndrome

  The team looks at whether changes in the FMR1 gene are linked to social language difficulties in people with autism, fragile X syndrome, and their family members.

  NIH research Northwestern University · Chicago, United States · NIH-11403972

• Mortality in Autism: Understanding Death Risk Across Ages in ASD

  This project looks at how likely people with autism are to die at different ages and what might influence those risks, using Medicaid data.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11402260

• Canine-assisted addition to group therapy for emotion dysregulation in kids with autism

  A study will test whether adding animal-assisted therapy to a proven group treatment helps reduce emotion dysregulation in children with autism.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11402213

• AIMS: Helping middle-schoolers with autism stay organized and do better in school

  This project tests a support program called AIMS to help middle-school children with autism manage homework, materials, and planning so they can achieve better grades and feel more confident in class.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11399819

• How an autism-linked gene (CHD8) affects dopamine brain circuits

  This work looks at how losing the autism-linked gene CHD8 changes dopamine brain cells and related behaviors that could matter for autistic children.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11398259

• Autism Risk in Babies Born Earliest (Preterm Birth)

  This project looks at whether being born early (before 37 weeks) changes how autism develops in children, especially compared with babies born on time.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11396513

• Longitudinal Brain and Behavior Study of Autism from Infancy to Adolescence

  This project follows children at risk for autism from infancy through adolescence to understand how brain development and behavior unfold over time.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11396475

• Understanding how Latino caregivers engage with early autism services

  This project looks at how Latino families engage with early intervention services for children with autism to improve access and quality of care.

  NIH research California State University Long Beach · Long Beach, United States · NIH-11396374

• Optimizing how parents teach kids with autism through sequencing evidence-based parent programs

  A study tests the best order to use two parent-led therapies for children with autism to improve social communication and reduce disruptive behavior.

  NIH research Northwestern University · Chicago, United States · NIH-11395302

Related topics

Quick answers

How many Autism clinical trials are recruiting right now?

81, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (53 trials), Italy (5 trials), United Kingdom (4 trials), Taiwan (3 trials), China (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 1: 4, Phase 2/3: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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