NIH-funded research R01 grant

Longitudinal brain and behavior study of autism from infancy through adolescence

Official title: A Longitudinal Brain and Behavior Study of Autism From Infancy Through Adolescence

Funded at Univ of North Carolina Chapel Hill · NIH-11478411 · Data updated 2026-11-12

A long-term study follows people at risk for autism from infancy into adolescence to understand how brain changes relate to autism over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startJuly 1, 2007
Project endAugust 31, 2027
Funding year2026
Award (this year)$8,016
NIH project number3R01HD055741-20S1
Project IDNIH-11478411 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are children with or without a family history of ASD who are followed from infancy into adolescence.

Less likely to help

Participants not experiencing outcomes related to brain/behavior trajectories may derive limited direct benefit.

What this research studies

This project tracks a large group of children with and without a family history of autism, using brain imaging and behavior assessments from infancy through adolescence. The study aims to map how early brain patterns emerge and evolve, and how they relate to later ASD features. Researchers collect detailed data at multiple ages to identify markers that predict outcomes and inform support strategies. The goal is to improve early understanding, diagnosis, and planning for families affected by autism.

Why it matters

Potential benefit: Findings could lead to earlier identification and better-tailored supports for autistic individuals as they grow.

How similar studies have gone: Previous work has shown early brain and behavior markers associated with later ASD, supporting further longitudinal insight.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Piven, Joseph — Univ of North Carolina Chapel Hill
  • Study coordinator: Piven, Joseph

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.