Trauma‑Focused Cognitive Behavioral Therapy adapted for autistic children and teens (pilot implementation)

Implementation Science-Guided Pilot Study of Trauma-Focused Cognitive Behavioral Therapy for Autistic Youth in Community Mental Health Settings

Not applicable Interventional Dartmouth-Hitchcock Medical Center · NCT07420478

This pilot will try TF‑CBT adapted for autistic children and teens with trauma-related symptoms to see if community mental health clinicians can deliver it and families find it acceptable.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages6 Years and up
SexAll
SponsorDartmouth-Hitchcock Medical Center Academic / other
Locations1 site (Lebanon, New Hampshire)
Trial IDNCT07420478 on ClinicalTrials.gov

What this trial studies

An open pilot will deliver a modified Trauma‑Focused Cognitive Behavioral Therapy (TF‑CBT) protocol to autistic youth aged 6–17 with moderate trauma-related distress and their non‑offending caregivers. Community mental health clinicians who are trained in TF‑CBT and employed at participating centers will provide the treatment in outpatient settings. Outcomes will focus on feasibility, acceptability, and symptom change measured with instruments such as the Child and Adolescent Trauma Screen‑2 (CATS‑2). The pilot tests implementation procedures in a real-world community mental health setting affiliated with Dartmouth‑Hitchcock and enrolls youth already on a participating clinician's caseload.

Who should consider this trial

Good fit: Autistic children and adolescents aged 6–17 with a current autism diagnosis, a moderate level of trauma-related distress on the CATS‑2, a non‑offending caregiver able to participate, and who are receiving outpatient care from a participating community mental health clinician.

Not a fit: Children who do not show trauma-related distress on the CATS‑2, who lack a non‑offending caregiver to participate, or who are not receiving care from a participating clinician are unlikely to benefit from this pilot.

Why it matters

Potential benefit: If successful, the adapted TF‑CBT could reduce trauma symptoms and increase access to effective trauma care for autistic youth in community clinics.

How similar studies have performed: TF‑CBT is well supported for treating trauma in neurotypical youth, but adaptations for autistic youth are relatively novel and have only limited pilot data so far.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria for Therapists

1. Employed as a clinician at a participating Community Mental Health Center (CMHC; publicly-funded mental health program) for at least 6 months.
2. Trained in TF-CBT.
3. Has an eligible autistic youth on current caseload (see below).

Inclusion Criteria for Child Participants

1. Between 6 and 18 years old (up to 17 years, 11 months).
2. Current medical diagnosis of autism.
3. Has a non-offending caregiver who is able to participate in treatment (i.e., caregiver who is not the perpetrator of the abuse/other trauma).
4. Initiated outpatient psychotherapy services from participating therapist within enrolled CMHC.
5. A moderate level of trauma-related distress as measured by the Child and Adolescent Trauma Screen-2 (CATS-2).

Exclusion Criteria for Child Participants

1\. Does not present with trauma-related distress (score falls within the "Normal" range as measured by the Child and Adolescent Trauma Screen-2 Self- and Parent-Report).

Where this trial is running

Lebanon, New Hampshire

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Autism Spectrum DisorderPTSD and Trauma-related SymptomsAutismTrauma and Stressor Related DisordersMental Health ServicesTraumaPTSDMental health symptoms
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.