NIH-funded research NIH-funded research

Sleep problems in autism and daily functioning

Official title: Project 1: The impact of sleep dysregulations on Autism Spectrum Disorder

Funded at Stanford University · NIH-11408805 · Data updated 2026-11-12

A large study at a major university is looking at how sleep problems affect children with autism and their daily lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 6, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$393,944
NIH project number5P50HD109861-05
Project IDNIH-11408805 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children and adolescents ages 4–17 with a confirmed autism spectrum disorder and age- and sex-matched peers without ASD.

Less likely to help

Very young children under 4 or individuals without ASD who do not experience sleep disturbances may see limited direct benefit.

What this research studies

This project will compare sleep patterns and daytime brain activity between children with autism and typically developing children, using home sleep monitoring, in-lab sleep testing, and resting EEG. It will enroll about 150 ASD and 75 control participants aged 4–17 years to see how sleep quality and architecture relate to core autism symptoms and cognitive function. By studying sleep in a natural home setting and in conjunction with daytime measurements, the study aims to clarify whether sleep disruptions contribute to the severity of ASD symptoms.

Why it matters

Potential benefit: If successful, the findings could lead to targeted sleep interventions that may lessen ASD symptom severity and improve daytime functioning.

How similar studies have gone: Previous work suggests sleep patterns differ in ASD, but this study uses home sleep testing and a larger sample to clarify links to symptoms.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: O'hara, Ruth M — Stanford University
  • Study coordinator: O'hara, Ruth M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.