Condition

Neurodevelopmental Disorders clinical trials and research

• 53Clinical trials
• 94NIH research projects
• 2New in 30 days
• 18Countries

Newest Neurodevelopmental Disorders clinical trials

All recruiting trials (53)

• Understanding brain development in congenital hypothyroidism: comparing affected children, healthy controls, and mild thyroid conditions

  This study tests how brain development in children with congenital hypothyroidism compares to similar children without the condition and to kids with a mild thyroid finding.

  Recruiting at 3 sites Istituto Giannina Gaslini · Genova and 2 other locations · NCT07893522

• Leopard: using multi-omics to boost genetic diagnosis for neurodevelopmental disorders

  This study tests a multi-omics approach to find genetic explanations for neurodevelopmental disorders in people with moderate-to-severe intellectual disability.

  Recruiting Istituto Giannina Gaslini · Genova · NCT07884227

• Melillo Method for kids with behavior and learning challenges

  This pilot test will see if the Melillo Method can be feasibly delivered in two Illinois schools to help kids aged 8 and up who have behavioral and learning difficulties.

  Recruiting Life University · Roodhouse, Illinois · NCT07779889

• Understanding how sensory brain signals vary in people with and without neurodevelopmental disorders

  This study tests whether people with neurodevelopmental disorders show more variation in brain responses to sensory stimulation than people without these disorders.

  Recruiting University Hospital, Tours · Tours · NCT07542977

• Two-week intensive brain-focused therapy program for children with neurodevelopmental and chromosomal conditions

  This program will try a two-week, individualized multimodal neurorehabilitation approach for children about 4–12 years old with neurodevelopmental or chromosomal conditions to see if it improves attention, motor skills, communication, and daily functioning.

  Recruiting Healing Hope International · The Woodlands, Texas · NCT07493096

• Social cognition testing for 8–16-year-olds with autism, ADHD, or atypical development

  This project will test a multidimensional social-cognition battery in French-speaking 8–16-year-olds with autism, ADHD, or atypical neurodevelopment to see if it better identifies social processing differences.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07439276

• Virtual reality to boost neuroplasticity in children and adolescents

  This project will try immersive virtual reality rehabilitation to improve attention, motor skills, social interaction, and quality of life in children and teens aged 8–18 with ADHD, autism, or cerebral palsy.

  Recruiting IRCCS Centro Neurolesi Bonino Pulejo · Messina, Messina · NCT07426315

• COPCA program for infants at risk of neurodevelopmental disorders

  This trial will try the COPCA coaching program with infants under 12 months who are at risk of neurodevelopmental disorders to see if it improves motor development and helps families feel more empowered.

  Recruiting University of Seville · Seville, Seville · NCT07387627

• Early spontaneous movements and later psychomotor outcomes in preterm and full-term infants

  This project will test whether the quality of early spontaneous movements in preterm and full-term infants predicts their motor, communication, sensory, and social development at 18 and 36 months.

  Recruiting at 3 sites Masaryk University · Pardubice, Czechia and 2 other locations · NCT07296003

• High- and low-frequency paired associative deep TMS for ADHD

  This trial tests whether high- or low-frequency paired deep transcranial magnetic stimulation (dTMS) to the prefrontal cortex can help adults with ADHD by balancing cortical arousal between the brain hemispheres.

  Recruiting Ben-Gurion University of the Negev · Beersheba · NCT07105475

• Exploring the impact of maternal microbiota on child health

  This study looks at how the bacteria in pregnant women's bodies affect their babies' health and development to see if it can help prevent future health issues.

  Recruiting Guangzhou Women and Children's Medical Center · Guangzhou · NCT06926166

• Reducing missed clinic appointments for neurodevelopmental evaluations

  This project will test different appointment reminder messages and a patient navigator to see if families scheduled for neurodevelopmental evaluations attend their appointments more reliably.

  Recruiting Phase 3 Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · Baltimore, Maryland · NCT06915480

• See how common neurodevelopmental disorders are among people who are homeless

  We’re testing how common autism, ADHD, and intellectual disability are among adults who are homeless in France.

  Recruiting Hôpital le Vinatier · Lyon, Auvergne-Rhône-Alpes · NCT06869915

• Identifying biomarkers for neurodevelopmental disorders linked to inflammation during pregnancy

  This study is trying to find signs that could help predict neurodevelopmental disorders in kids whose moms had inflammation during pregnancy.

  Recruiting Istituto Clinico Humanitas · Pisa, PI · NCT06852703

• Evaluating gene expression changes in children on antipsychotic medications

  This study is trying to see how antipsychotic medications affect the genes of children and teens with metabolic disorders, compared to those who don't take these medications, to find early signs of possible health issues.

  Recruiting IRCCS Eugenio Medea · Bosisio Parini, LC · NCT06814314

• Assessing motor and voice development in infants

  This study is trying to see if watching videos of infants can help spot early signs of physical disabilities, especially for those at risk of Cerebral Palsy, by looking at their movement and voice development.

  Recruiting Ohio State University · Columbus, Ohio · NCT06807203

• Pai.ACT: AI-powered chatbot-assisted ACT for parents of children with neurodevelopmental disorders

  This trial tests a chatbot-guided ACT program for Cantonese-speaking parents of young children with neurodevelopmental disorders to see if it helps reduce parenting stress and improves family well-being.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06779422

• Understanding how GEMIN5-related neurodevelopmental disorder develops over time

  We will collect medical records, clinic exam data, and blood samples to see how GEMIN5-related neurodevelopmental disorder progresses in people of all ages who have two GEMIN5 gene mutations.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06776341

• Inclusive physical activity program for adults with intellectual disabilities

  This study is testing a new fitness program for adults with intellectual disabilities to see if it helps them be more active and feel better over 16 weeks.

  Recruiting University of North Carolina, Chapel Hill · Fayetteville, Arkansas and 1 other locations · NCT06740162

• Improving child mental health services in China using a training program for teachers

  This study is testing whether training kindergarten teachers in a new mental health program can improve the support and care for children with mental and behavioral issues in China.

  Recruiting at 4 sites Sun Yat-sen University · Zhongshan, Guangdong and 8 other locations · NCT06702410

• Diagnosing neurodevelopmental disorders in adults

  This study is looking to see how we can better identify neurodevelopmental disorders like ADHD and autism in adults who were diagnosed after 18, so they can get the support they need.

  Recruiting Hospices Civils de Lyon · Bron · NCT06691048

• Learning words through parentese in autistic children

  This study is testing if using a special way of talking called parentese helps autistic children learn new words better when it's done through videos compared to live interactions.

  Recruiting The University of Texas at Dallas · Richardson, Texas · NCT06649916

• Educator training to improve social engagement during recess for autistic students

  This study is testing a coaching program for educators to help autistic students and their classmates get along better during recess.

  Recruiting University of Washington · Los Angeles, California and 2 other locations · NCT06559267

• Genetics Navigator: a digital platform to guide people through genetic testing

  This randomized trial will test whether the Genetics Navigator digital platform helps adults and parents of children referred for clinical genetic testing have less distress and a smoother testing process compared with usual genetics appointments.

  Recruiting at 3 sites Unity Health Toronto · Toronto, Ontario and 2 other locations · NCT06455384

• Screening for neurodevelopmental disorders in children with congenital heart disease

  This study tests if regular check-ups can help find neurodevelopmental disorders in young children with congenital heart disease.

  Recruiting University Hospital, Montpellier · Montpellier and 2 other locations · NCT06431269

• Observing the link between allergies and neurodevelopmental disorders in infants in China

  This study looks at whether allergies in infants are linked to developmental issues like autism and ADHD to help understand how they might affect young children's growth and learning.

  Recruiting Qilu Hospital of Shandong University · Jinan, Shandong · NCT06327906

• Evaluating patterns in neurodevelopmental disorders

  This study is trying to find common signs and causes of neurodevelopmental disorders like Autism and Down Syndrome to help with earlier diagnosis and better outcomes for those affected.

  Recruiting Rossignol Medical Center · Phoenix, Arizona · NCT06213090

• Using weighted blankets to improve sleep in children with ADHD

  This study is testing whether using weighted blankets can help children with ADHD, ages 5 to 12, sleep better.

  Recruiting University Hospital Bispebjerg and Frederiksberg · Frederiksberg · NCT06194162

• Evaluating brain blood flow regulation in infants with congenital heart disease

  This study looks at how blood flow to the brain works in infants with congenital heart disease to see if it affects their brain development and helps create better follow-up care for them.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT06190210

• HeartGPS: Prenatal psychological support for parents and babies after a single ventricle heart diagnosis

  This study tests whether an eight-session prenatal psychological program (HeartGPS) for parents of fetuses with single ventricle congenital heart disease can reduce parent distress and support fetal and infant brain and developmental outcomes.

  Recruiting Children's Hospital Medical Center, Cincinnati · Los Angeles, California and 3 other locations · NCT06175104

• Understanding motor behavior in high-risk infants

  This study is trying to understand how movement and muscle development in high-risk infants, like those born early or with brain injuries, compare to typically developing infants to help find better ways to support their growth.

  Recruiting University Hospital, Geneva · Geneva · NCT06111898

• Intervention to support neurodevelopment in preterm infants

  This study tests a special program for preterm infants that includes skin-to-skin contact with parents and soothing sounds to see if it helps their brain development.

  Recruiting St. Justine's Hospital · Montreal, Quebec and 1 other locations · NCT06087744

• Comparing Sertraline and Placebo for Treating Anxiety in Children with Neurodevelopmental Disorders

  This study is testing if the medication sertraline can help reduce anxiety in children and teens aged 8-17 with neurodevelopmental disorders like autism and Fragile X syndrome compared to a placebo.

  Recruiting at 6 sites Phase 2 Holland Bloorview Kids Rehabilitation Hospital · Calgary, Alberta and 6 other locations · NCT06081348

• Parent-child yoga to help children with congenital heart disease focus better

  This study is testing if parent-child yoga can help children with congenital heart disease focus better and improve their overall well-being.

  Recruiting at 2 sites St. Justine's Hospital · Montreal, Quebec and 1 other locations · NCT05997680

• Improving early detection of cerebral palsy in infants in Ireland

  This study is trying to find out if a new way of checking for cerebral palsy can help doctors spot it earlier in high-risk infants in Ireland.

  Recruiting at 4 sites University College Cork · Cork and 4 other locations · NCT05907837

• Observational study on medical cannabis use in children

  This study is looking at how medical cannabis affects children aged 3 to 17 with various health issues, including cancer, by tracking their pain, sleep, mood, behavior, and seizures over two years.

  Recruiting University of Manitoba · Winnipeg, Manitoba · NCT05863910

• Early detection and referral for autism and developmental disorders in infants at maternal and child clinics

  This study tests two ways of screening babies during routine clinic visits to see if they find infants under one year at risk for autism or other developmental disorders so they can be referred earlier.

  Recruiting Centre Hospitalier Intercommunal Creteil · Champigny-sur-Marne · NCT05815095

• Study on factors influencing neurodevelopmental disorders in mothers and children

  This study looks at how both genetics and the environment might affect the development of neurodevelopmental disorders like Autism Spectrum Disorder in mothers and their children.

  Recruiting University Hospital, Montpellier · Montpellier · NCT05681923

• Early EEG monitoring in children with congenital heart disease to predict neurodevelopmental disorders

  This study is trying to see if early brain wave patterns in babies with heart problems can help predict future learning and development issues.

  Recruiting University Hospital, Lille · Lille, Hauts-de-France · NCT05658965

• Focused Acceptance and Commitment Therapy for Parents of Children with Special Healthcare Needs

  This study is trying out a video-based therapy program to see if it can help parents of children with special healthcare needs feel less stressed and improve their parenting during tough times.

  Recruiting at 5 sites Chinese University of Hong Kong · Hong Kong and 4 other locations · NCT05584059

• Assessing motor and cognitive development in infants using wearables

  This study is testing a special wearable garment to see how it can help track the motor and cognitive development of infants, both those developing normally and those at risk for developmental issues.

  Recruiting Helsinki University Central Hospital · Helsinki · NCT05527080

• Screening siblings of children with autism for neurodevelopmental disorders

  This study is testing a new way to check if siblings of children with autism have any neurodevelopmental disorders to better understand their needs.

  Recruiting University Hospital, Montpellier · Montpellier · NCT05512637

• Registry for individuals with Rett syndrome

  This study is gathering information from people with Rett syndrome and their caregivers to help improve care and develop new treatments for the condition.

  Recruiting at 19 sites International Rett Syndrome Foundation · Birmingham, Alabama and 18 other locations · NCT05432349

• Evaluating the effects of xylitol during pregnancy on child development

  This study is testing if taking xylitol during pregnancy helps with the brain development of children aged 4 to 8 years, comparing two different ways to measure their progress.

  Recruiting University of Washington · Lilongwe · NCT05361122

• Understanding long-term effects of breathing patterns in preterm infants

  This study looks at how breathing problems in preterm babies might affect their chances of developing asthma, sleep issues, and learning difficulties as they grow up.

  Recruiting Ann & Robert H Lurie Children's Hospital of Chicago · Chicago, Illinois · NCT05336890

• Remote genetic evaluation for children with rare disorders

  This study is testing a new online service to help kids with rare disorders along the Texas-Mexico border get faster genetic evaluations and better healthcare support.

  Recruiting Baylor College of Medicine · Edinburg, Texas · NCT05318222

• Understanding Developmental Coordination Disorder in Children and Young Adults

  This study is trying new exercises to see if they can help children and young adults with Developmental Coordination Disorder improve their movement skills and overall quality of life.

  Recruiting Hospices Civils de Lyon · Bron, Auvergne-Rhône-Alpes · NCT05154799

• Impact of Labor Pain Relief on Child Development

  This study looks at whether using epidurals for pain relief during labor affects how children develop by the time they are two years old.

  Recruiting at 2 sites Peking University First Hospital · Beijing, Beijing Municipality and 1 other locations · NCT04964206

• Impact of perinatal COVID-19 on infant development

  This study looks at how COVID-19 infection during pregnancy might affect the development of newborns' hormones and whether this could lead to long-term developmental issues.

  Recruiting University Hospital, Lille · Lille and 1 other locations · NCT04952870

• Exploring how vestibular function affects children's cognitive and motor development

  This study is trying to see how problems with balance and movement affect the thinking and physical skills of school-aged children, including those with developmental disorders.

  Recruiting University Ghent · Ghent · NCT04685746

• Investigating early life environmental impacts on health in Shenzhen

  This study is trying to see how the environment during pregnancy affects the health of mothers and their children in Shenzhen, China, over seven years.

  Recruiting Sun Yat-sen University · Shenzhen, Guangdong · NCT03830879

• Observational study of genetic variants in neurodevelopmental disorders

  This study looks at how certain genetic changes affect people with neurodevelopmental disorders like autism and intellectual disabilities to better understand their treatment and related health issues.

  Recruiting Columbia University · New York, New York · NCT03492060

• Home-use treatment for autism using Autowave technology

  This study is testing a home device that uses special wave technology to see if it can help improve the behavior and thinking skills of people with autism.

  Recruiting at 2 sites American Federation of Medical Synergetics · Louisville, Kentucky and 1 other locations · NCT03222375

NIH-funded research (newest 40 of 94)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Intergenerational factors in neurodevelopmental disorders

  This project looks at how experiences before and during pregnancy across generations may influence the risk of neurodevelopmental conditions like ADHD, autism, and related disorders in grandchildren.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11583822

• Understanding brain signals in autism to identify biologically distinct subtypes

  This study uses EEG to link how the brain processes sensory information with behavior in young children with autism and related concerns.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11532027

• Clinical Translational Research Center for Neurodevelopmental Disorders

  A funded center supports research on neurodevelopmental disorders like Angelman syndrome and autism to better understand causes and improve treatments for children.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11522710

• Synaptic nanostructure in neurodevelopmental disorders

  This project aims to map the tiny architecture of brain synapses in native cells to understand how connections form and change in neurodevelopmental disorders.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11519386

• Maternal acetaminophen use in pregnancy and ADHD risk in children

  A large study will follow thousands of mother-child pairs to see if taking acetaminophen during pregnancy relates to ADHD in kids.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11434804

• GDF11’s role in brain development and autism-related disorders

  A new NIH grant tests whether adjusting a growth factor called GDF11 can improve brain function and behaviors in models related to autism and other neurodevelopmental disorders.

  NIH research University of Virginia · Charlottesville, United States · NIH-11432464

• DOT1L chromatin regulator and neurodevelopmental disorders

  A study to understand how changes in the DOT1L chromatin regulator affect brain development and contribute to neurodevelopmental disorders in people.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11386595

• Gaining insights into how Noonan syndrome mutations affect brain development and neurodevelopmental disorders

  This project studies how specific Noonan syndrome gene mutations shape brain development and related disorders in children.

  NIH research Stanford University · Stanford, United States · NIH-11384519

• Understanding how JNK signaling affects autism and related neurodevelopmental disorders

  This grant studies how a cellular communication pathway called JNK affects brain development and may explain why some kids develop autism or intellectual disability.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11383141

• Radiomics analysis of brain MRIs from kids to help understand autism and related neurodevelopmental concerns

  A pediatric brain MRI study will look at imaging data from real patient scans to find patterns that could improve understanding of autism and other neurodevelopmental issues in children.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11370211

• Context-dependent disease mechanisms in neurodevelopmental disorders (16p11.2)

  A human-cell study from UCLA will explore how genetic risk for autism and ADHD affects early brain development, using patient-derived stem cells to test how cells respond to developmental signals.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11366753

• Longitudinal look at self-injury and family life in teens with neurodevelopmental differences

  This grant supports a long-term study of self-injury in adolescents with neurodevelopmental disorders and how families influence risk and protection over time.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11366213

• Noncoding RNAs and Autism: How RNA Elements Shape Neurodevelopment

  Researchers are studying how long noncoding RNAs in the brain may influence autism and related neurodevelopmental disorders so future treatments could target these RNA pieces.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11365359

• Molecular and cellular clues about cerebellar problems in neurodevelopmental disorders

  This grant looks at how the cerebellum may contribute to neurodevelopmental disorders like ADHD and autism, to understand why movement, thinking, and behavior can be affected.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11365173

• Cerebellar cytoskeleton clues to neurodevelopmental disorders

  A study to understand how a protein in brain cells called βII-spectrin affects cerebellar circuits and contributes to disorders like ADHD, autism, and epilepsy in children.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11364222

• TRIO GEF1 in neurodevelopmental disorders and autism

  Researchers are studying how changes in a brain protein called TRIO might contribute to autism and related conditions, with the goal of finding new ways to prevent or treat these disorders.

  NIH research Yale University · New Haven, United States · NIH-11360117

• Gene dosage and brain development in 17p- syndrome and autism

  A study using human cell models to understand how changes in a gene called RAI1 affect brain development in people with 17p- syndrome and autism.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11356547

• Noncoding DNA changes linked to neurodevelopmental disorders

  Researchers are studying how rare noncoding DNA changes might contribute to autism and related developmental conditions in people, to better understand why these disorders occur.

  NIH research Washington University · Saint Louis, United States · NIH-11355565

• Kinase signaling in brain development and autism at Duke

  A Duke-led center is exploring how protein kinase signaling affects brain development and its link to autism and related disorders.

  NIH research Duke University · Durham, United States · NIH-11348636

• Brain organoids to understand neurodevelopmental disorders

  A researcher will study patient-derived brain organoids to better understand how neurodevelopmental disorders develop and why they cause lifelong challenges.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11335564

• Chromatin changes that affect brain development in autism and intellectual disability

  Researchers are looking at how mutations in a chromatin protein called H1.4 change gene activity in developing brain cells to better understand Rahman syndrome, autism, and intellectual disability.

  NIH research Duke University · Durham, United States · NIH-11332799

• Common environmental chemicals that may harm developing brains linked to autism and ADHD

  This work finds which everyday environmental chemicals might damage developing brains and raise risk for autism or ADHD.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11327314

• How calcium channel problems contribute to autism and developmental delays

  This project links changes in brain calcium channels to autism and related developmental conditions to understand how altered calcium signaling affects nerve cell communication.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11321279

• Intergenerational factors shaping neurodevelopmental disorders

  A large NIH-backed study will look across generations to understand how a grandparent’s pregnancy and a parent’s early life may influence a child’s risk of ADHD, autism, and other neurodevelopmental issues.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11317592

• Using sensory brain responses to find brain-based subtypes in autism and related conditions

  This project records brain activity with EEG in 3–4 year-old children with autism or sensory concerns to find brain-based groups that relate to behavior.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11314597

• UTR variants in neurodevelopmental disorders: a fast track to understanding autism biology

  A research project at Washington University aims to understand how non-coding UTR regions of genes influence autism-related conditions by testing many variants in brain-relevant cells.

  NIH research Washington University · Saint Louis, United States · NIH-11308240

• TAOK1 enzyme and its role in autism and brain development

  This project is looking at whether problems in a brain enzyme called TAOK1 change nerve cell shape and function in people with autism and related developmental delays.

  NIH research University of Washington · Seattle, United States · NIH-11299039

• How SYNGAP1 affects early brain development in autism and related disorders

  Researchers are looking at how changes in the SYNGAP1 gene alter early brain cell behavior in people with autism, schizophrenia, or intellectual disability.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11292388

• ZNF292: understanding its role in brain development and autism-related disorders

  Researchers are studying how changes in a gene called ZNF292 affect brain development and contribute to autism and related conditions.

  NIH research Washington University · Saint Louis, United States · NIH-11290145

• Tiny synapse structures in autism and related conditions

  Researchers are mapping the tiny molecular machinery that helps brain cells talk to each other to understand how autism-linked changes disrupt that communication.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11254905

• RNA-based therapy for a rare brain disorder

  A patient-facing plan to develop targeted RNA medicines that could help people with a rare brain disorder caused by a single gene mutation.

  NIH research Dayi Therapeutics, INC. · New York, UNITED STATES · NIH-11251787

• Meningeal lymphatic drainage and behavior in Fragile X syndrome

  The team is testing whether fixing brain lymphatic drainage can improve social and behavioral problems in people with Fragile X syndrome.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11248020

• How lab-grown human mini-brains reveal causes of developmental and psychiatric brain disorders

  Researchers are using lab-grown human brain organoids to learn how genetic and environmental changes alter brain cell activity in people with developmental and psychiatric conditions.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11243541

• Understanding how cerebrospinal fluid affects brain development in infants with Down Syndrome.

  This study is looking at how the fluid around the brain affects the growth and development of babies with Down Syndrome and similar conditions, to help find ways to support their brain health as they grow.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11242628

• Creating RNA treatments for rare brain disorders

  This study is exploring new RNA-based treatments for rare brain disorders caused by single gene changes, aiming to help those affected by these conditions by restoring normal gene function and offering hope for better care.

  NIH research Dayi Therapeutics, INC. · College Station, United States · NIH-11239933

• Gene dosage and brain disorders: how genetic changes shape autism, bipolar disorder, and related conditions

  Researchers will study how different genetic changes influence brain-related conditions like autism and bipolar disorder using large patient data to understand why these disorders overlap and co-occur.

  NIH research Geisinger Clinic · Danville, United States · NIH-11239795

• How the autistic brain changes as people age

  This project looks at brain cells and signs of inflammation in adults with autism to understand memory and thinking changes as they get older.

  NIH research University of California at Davis · Davis, United States · NIH-11235171

• Integrated human forebrain organoids to study neurodevelopmental disorders

  A Yale team will grow complex lab-grown brain tissue models to study how autism-related genes affect brain development.

  NIH research Yale University · New Haven, United States · NIH-11234499

• How manganese exposure and genes may raise ADHD risk

  This project looks at whether early-life exposure to manganese together with genetic differences changes dopamine in the brain and increases ADHD risk in children and adolescents.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11196758

• Early-life air pollution and children's brain development

  This project looks at whether breathing tiny air pollution particles before and shortly after birth changes brain metal levels and inflammation in ways that could raise the risk of autism, ADHD, or related childhood brain disorders.

  NIH research University of Rochester · Rochester, United States · NIH-11176833

Related topics

Quick answers

How many Neurodevelopmental Disorders clinical trials are recruiting right now?

53, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in United States (15 trials), France (11 trials), Italy (5 trials), China (5 trials), Canada (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →