Understanding sensory characteristics in autism spectrum disorder
Sensory Phenotypes of Autism Spectrum Disorder Across Lifespan: Prospective Cohort Study and Sensory-Social Paradigm Establishment
This study is trying to understand how people with autism experience their senses and how these sensory experiences affect their social interactions as they grow older.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 480 (estimated) |
| Ages | 18 Months and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05829161 on ClinicalTrials.gov |
What this trial studies
This observational project aims to establish sensory phenotypes in a Taiwanese cohort with autism spectrum disorder (ASD) across their lifespan. It will explore various sensory modalities and domains, as well as their clinical correlates. The study will also investigate the relationship between sensory phenotypes and social impairments, specifically focusing on eye gaze avoidance and social touch anxiety, using fMRI and EEG techniques. By quantifying sensory characteristics, the research seeks to provide a clearer understanding of how these features change with age and impact social interactions.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 12-40 years with a diagnosis of autism spectrum disorder.
Not a fit: Patients without a diagnosis of autism spectrum disorder or those with major psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of sensory issues in ASD, leading to better support and interventions for individuals affected by these challenges.
How similar studies have performed: While there is ongoing research into sensory characteristics in ASD, this study's comprehensive approach to examining sensory phenotypes across the lifespan is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Aim#1 Inclusion Criteria: * Diagnosis of autism spectrum disorder Aim#2 and #3 ASD group: Inclusion Criteria: * Diagnosis of autism spectrum disorder * Age above 12-40 years old Exclusion Criteria: * No diagnosis of autism spectrum disorder * Pregnant woman * Metal implant in the body TD group: Inclusion Criteria: * No diagnosis of autism spectrum disorder * Age above 12-40 years old Exclusion Criteria: * History of major psychiatric disorders * Pregnant woman * Metal implant in the body
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Yi Ling Chien — National Taiwan University Hospital
- Study coordinator: Yi Ling Chien
- Email: ylchien@hotmail.com
- Phone: 886-2-2312-3456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.