Exploring how early life experiences affect brain and behavior

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the influence of early life experiences, such as adoption and trauma, on brain development, behavior, and the immune system in young adults. Participants will undergo a series of assessments including psychological questionnaires, online cognitive games, and brain imaging via fMRI. The goal is to enhance understanding of how these experiences can lead to mental health challenges later in life, ultimately aiding in the identification of individuals at risk for future issues. By gathering comprehensive data, the study seeks to inform interventions that can provide timely support to vulnerable populations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-24
* Reside in Greater Manchester
* You are not enrolled on a university degree course and do not hold a university degree qualification
* Lived with one or both birth parents throughout childhood.
* Able to travel to the University of Manchester
* Able to understand the study information and participate in the assessment procedures described below (independently or with reading support from a researcher, friend or family member)
* Able to read text on a computer screen (using glasses or contact lenses if required)
* To sign up for this study one or more of the following statements should apply to you:

  1. I am not currently in education employment or training, or I am unemployed.
  2. I receive benefits from the Government e.g., housing benefits, universal credit, personal independent payment (PIP), disability benefit, job seekers allowance.
  3. I am currently struggling due mental health problems or neurodiversity (e.g., depression, anxiety, ADHD, autism, eating disorder)

Exclusion Criteria:

* You were looked after by the local authority (e.g., foster, kinship care or residential children's home) or adopted during childhood.
* Any experience of childhood trauma (including neglect, physical/verbal abuse, sexual abuse or exposure to domestic violence).
* Your family required input from social services due to child protection concerns.
* You are experiencing symptoms of and have been diagnosed with Post-Traumatic Stress Disorder (PTSD), borderline personality disorder (BPD), Emotionally Unstable Personality Disorder (EUPD).

Where it's running

• Faculty of Biology Medicine & Health, University of Manchester
  Manchester, United Kingdom Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.