NIH-funded research NIH-funded research

Neural roots of how autistic adults understand word meaning

Official title: Neural bases of semantic language challenges in autism

Funded at Ut Southwestern Medical Center · NIH-11640092 · Data updated 2026-11-12

A study to understand how adults with autism process word meanings in the brain, aiming to improve language support.

More Autism research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center
NIH-funded
Lab location1 site (Dallas, United States)
Project startSeptember 18, 2026
Project endAugust 31, 2027
Funding year2026
Award (this year)$659,399
NIH project number1R56DC023225-01A1
Project IDNIH-11640092 on NIH RePORTER

Who could benefit from this research

Could help

Adults (21+ years) with autism who experience semantic language difficulties and are able to undergo brain imaging.

Less likely to help

Individuals without language difficulties or those unable to participate in brain-imaging procedures may not benefit.

What this research studies

This project focuses on adults with autism who have language challenges, exploring how their brains process word meanings across a wide range of words and semantic categories. It shifts beyond traditional brain imaging by sampling more words and looking at the whole brain, including the cerebellum, to uncover why semantic language is difficult for some individuals with ASD. The findings could inform more effective, less burdensome language therapies in the future. Participants may contribute brain imaging data and related assessments to help map semantic processing in ASD.

Why it matters

Potential benefit: Better understanding of semantic language in ASD could lead to more targeted and efficient language therapies for autistic adults.

How similar studies have gone: Prior research shows semantic language processing differences in ASD, with new approaches promising broader brain sampling and cerebellar involvement, but results are still evolving.

Where this research is happening

  • Ut Southwestern Medical Center
    Dallas, United States
    Active

Researchers

  • Principal investigator: Dmello, Anila — Ut Southwestern Medical Center
  • Study coordinator: Dmello, Anila

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.