NIH-funded research R01 grant

Longitudinal Brain and Behavior Study of Autism from Infancy to Adolescence

Official title: A Longitudinal Brain and Behavior Study of Autism From Infancy Through Adolescence

Funded at Univ of North Carolina Chapel Hill · NIH-11396475 · Data updated 2026-11-12

This project follows children at risk for autism from infancy through adolescence to understand how brain development and behavior unfold over time.

More Autism research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startJuly 1, 2007
Project endAugust 31, 2027
Funding year2026
Award (this year)$2,138,714
NIH project number5R01HD055741-20
Project IDNIH-11396475 on NIH RePORTER

Who could benefit from this research

Could help

Children from infancy through adolescence, including those at high familial risk for autism and those at low risk.

Less likely to help

The study is observational and may not directly provide individual treatments or therapies.

What this research studies

A long-term study monitors brain scans and behavioral assessments of hundreds of children, some with a family history of autism and some without. Researchers collect data at multiple ages from infancy into adolescence to identify early brain patterns and how they relate to autism as they grow. The study aims to map how autism-related features emerge, change during childhood, and relate to later outcomes, including mental health during teen years. Findings could help families understand development and guide early supports, education, and interventions.

Why it matters

Potential benefit: Better understanding of how autism develops could lead to earlier detection and more targeted supports for autistic individuals and their families.

How similar studies have gone: Previous analyses have shown early brain and behavioral markers that predict later autism, with significant longitudinal insights across early development.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Piven, Joseph — Univ of North Carolina Chapel Hill
  • Study coordinator: Piven, Joseph

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.