Using fecal microbiota transplantation to treat gut disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the safety and efficacy of fecal microbiota transplantation (FMT) as a treatment for various gastrointestinal disorders, including Crohn's disease, ulcerative colitis, and irritable bowel syndrome. FMT involves infusing feces from healthy donors into patients to restore a balanced gut microbiota, which is crucial for overall health. The study aims to evaluate the effectiveness of this approach in alleviating symptoms and improving the quality of life for patients suffering from these conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Confirmed diagnosis of any of the following diseases:

* Crohn's disease
* Ulcerative colitis
* Celiac disease
* Irritable bowel syndrome
* Functional dyspepsia
* Constipation
* Antibiotic-associated diarrhea or any antibiotic- associated complications/symptoms
* Metabolic syndrome such as diabetes mellitus and obesity
* Multidrug-resistant infection
* Hepatic encephalopathy
* Multiple sclerosis
* Pseudo-obstruction
* Carbapenem-resistant Enterobacteriaceae (CRE) or Vancomycin-resistant Enterococci (VRE) infection
* Multiple organ dysfunction
* Dysbiotic bowel syndrome
* MRSA enteritis
* Pseudomembranous enteritis
* Alopecia, autism
* Graft-versus-host disease
* Idiopathic thrombocytopenic purpura (ITP)
* Atopy or allergy
* Liver disease such as Nonalcoholic fatty liver disease (NAFLD) and Nonalcoholic steatohepatitis (NASH)
* Alcohol dependence
* Psoriatic arthropathy that has suboptimal control of disease despite standard treatment.

Exclusion Criteria:

* Known contraindication to all FMT infusion method such as nasoduodenal tube insertion, oesophago-gastro-duodenoscopy (OGD), enteroscopy, colonoscopy and enema
* Any conditions that may render the efficacy of FMT or at the discretion of the investigators
* Current pregnancy

Where it's running

• The Chinese University of Hong Kong
  Hong Kong, Shatin, Hong Kong Recruiting

Study contacts

• Principal investigator: Siew Ng — Chinese University of Hong Kong
• Study coordinator: Matthew Fung
• Email: mfung@cuhk.edu.hk
• Phone: +852 35053855

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.