Condition

Abdominal Aortic Aneurysm clinical trials and research

• 22Clinical trials
• 37NIH research projects
• 19Countries

Newest Abdominal Aortic Aneurysm clinical trials

All recruiting trials (22)

• Cardiovascular Rehabilitation After Abdominal Aortic Aneurysm Repair

  This study tests whether a structured cardiovascular rehabilitation program after abdominal aortic aneurysm repair leads to better fitness and quality of life than standard postoperative care.

  Recruiting Medical University Innsbruck · Innsbruck, Tyrol · NCT07690046

• Imaging inflammation in abdominal aortic aneurysm using a PET tracer

  Researchers are testing whether a new PET tracer, 64Cu-DOTA-ECL1i, can image inflammation in an abdominal aortic aneurysm.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07548099

• Poland–Italy Aortic Bridge Registry: PERCUTEK Tycheseal for Abdominal Aortic Aneurysm

  This registry will see how well the PERCUTEK Tycheseal stent-graft works and how safe it is for adults having endovascular repair of abdominal aortic aneurysms.

  Recruiting at 21 sites American Heart of Poland · Castel Volturno and 25 other locations · NCT07476196

• PET scan to image MMP activity in abdominal aortic aneurysm

  We will test whether a new PET tracer ([64Cu]-RYM2) can safely image MMP activity in people with abdominal aortic aneurysm and in healthy volunteers.

  Recruiting Early Phase 1 Washington University School of Medicine · St Louis, Missouri · NCT07473102

• CTA registry for abdominal aortic aneurysm measurements

  This registry will collect CT angiography scans from people with abdominal aortic aneurysms to see if CTA measurements reliably describe aneurysm size and features.

  Recruiting RenJi Hospital · Shanghai · NCT07039825

• Cygnum aneurysm sac lining used with EVAR for abdominal aortic aneurysm

  This trial will test whether adding the Cygnum sac lining to standard EVAR is safe and helps prevent type II endoleaks in people with abdominal aortic aneurysms.

  Recruiting Life Seal Vascular Inc. · Auckland · NCT07020611

• Evaluation of a 3D-Printed Stent-Graft for Aortic Aneurysms

  This study is testing a new 3D-printed stent-graft to see if it works better and is safer than standard devices for treating complex abdominal aortic aneurysms in about 100 patients.

  Recruiting Samodzielny Publiczny Szpital Kliniczny nr 2 PUM · Szczecin, West Pomeranian Voivodeship · NCT06969729

• Longitudinal study of patients with Abdominal Aortic Aneurysm in Barcelona

  This study is tracking patients with Abdominal Aortic Aneurysm in Barcelona to see how their condition changes over time and what happens to them until they need surgery or experience other serious outcomes.

  Recruiting Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Barcelona, Catalonia · NCT06827652

• Investigating the link between abdominal aortic aneurysm and primary lung cancer

  This study is trying to see if there's a connection between abdominal aortic aneurysms and lung cancer by looking at the health and habits of 2000-3000 lung cancer patients.

  Recruiting at 2 sites First Affiliated Hospital of Kunming Medical University · Kunming, Yunnan and 1 other locations · NCT06775821

• Improving pain control after abdominal aortic aneurysm surgery

  This study tests which pain relief method works better for adults after surgery for abdominal aortic aneurysms: an epidural or a series of injections in the abdominal muscles.

  Recruiting IRCCS Policlinico S. Donato · San Donato Milanese, Milan · NCT06244732

• Nectero EAST System treatment for small-to-mid abdominal aortic aneurysms

  This will test a single, locally delivered endovascular treatment (Nectero EAST System) to try to stabilize small-to-mid abdominal aortic aneurysms in adults instead of routine surveillance.

  Recruiting at 38 sites Phase 2/3 Nectero Medical, Inc. · Scottsdale, Arizona and 41 other locations · NCT06001918

• Observational registry for the Ovation Alto Endograft in treating abdominal aortic aneurysms

  This study is testing the safety and effectiveness of a new device called the Ovation Alto Endograft for treating abdominal aortic aneurysms in patients who need surgery.

  Recruiting at 9 sites DGM Vascular · Palma de Mallorca, Balearic Islands and 8 other locations · NCT05823519

• Screening for abdominal aortic aneurysms using portable ultrasound in general practice

  This study tests whether using portable ultrasound in regular doctor's offices can help find abdominal aortic aneurysms earlier in men aged 65 to 75 who smoke or have smoked, and in people aged 50 to 75 with a family history of the condition.

  Recruiting at 6 sites Fondation Ophtalmologique Adolphe de Rothschild · Lyon and 5 other locations · NCT05617326

• Comparing two stent graft systems for treating abdominal aortic aneurysms

  This study is testing which of two different stent graft systems works better for treating abdominal aortic aneurysms in patients.

  Recruiting at 63 sites Medtronic Cardiovascular · Loma Linda, California and 67 other locations · NCT05378347

• Registry for patients treated with ALTO endograft for abdominal aortic aneurysm

  This study looks at how well the ALTO stent graft works for people having surgery to fix abdominal aortic aneurysms and what outcomes they experience afterward.

  Recruiting at 2 sites Azienda Ospedaliera Universitaria Senese · Rome and 1 other locations · NCT05234892

• Endovascular repair for complex aortic conditions using modified grafts

  This study is testing a new type of graft to see if it can safely and effectively repair complex aortic problems in high-risk patients who can't have traditional surgery.

  Recruiting Beth Israel Deaconess Medical Center · Boston, Massachusetts · NCT04746677

• Using metformin to slow the growth of abdominal aortic aneurysms

  This study is testing if the diabetes drug metformin can help slow down the growth of dangerous abdominal aortic aneurysms in people who meet certain health criteria.

  Recruiting Phase 2 Stanford University · Stanford, California · NCT04500756

• Italian registry of open and semi-conversion surgery after EVAR

  This project collects information to see how open or semi-conversion surgery works for people who have late complications after endovascular abdominal aortic aneurysm repair (EVAR).

  Recruiting Azienda Ospedaliero-Universitaria di Parma · Parma · NCT04299984

• Registry for safety and performance of Terumo Aortic endovascular grafts

  This study is collecting information from patients with abdominal and thoracic aortic aneurysms to see how safe and effective Terumo Aortic stent-grafts are in real-life use.

  Recruiting at 50 sites Vascutek Ltd. · Long Beach, California and 57 other locations · NCT04246463

• Using non-invasive tests to predict cardiovascular events in patients with abdominal aortic aneurysm

  This study is trying to see if non-invasive tests can help predict serious heart problems in patients with abdominal aortic aneurysm who are getting treatment.

  Recruiting at 7 sites Rijnstate Hospital · Nijmegen, Gelderland and 6 other locations · NCT04183426

• Assessing Aortic Wall Properties Using Advanced Imaging Techniques

  This study is testing new imaging techniques to see how the aorta behaves in patients with Abdominal Aortic Aneurysm and how this relates to their treatment outcomes over a year.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT02548546

• Using Magnetic Resonance Elastography to assess abdominal aortic aneurysms

  This study is testing if a new imaging technique can help doctors better understand the risk of rupture in abdominal aortic aneurysms by measuring how stiff they are.

  Recruiting Ohio State University · Columbus, Ohio · NCT02387255

NIH-funded research (37)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How the small regulator miR-146a affects abdominal aortic aneurysm

  This project aims to see if boosting a natural genetic regulator called miR-146a can help slow or prevent growth and rupture of abdominal aortic aneurysms in people with this condition.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-11453518

• MOF’s role in weakening the aorta and stopping aneurysm growth

  Scientists are studying how a molecule called MOF and inflammatory signals affect abdominal aortic aneurysms to find ways to slow or stop their enlargement.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11424572

• Endovascular Suturing Device to Improve Endograft Fixation in Abdominal Aortic Aneurysm

  A new device aims to better secure endografts during EVAR for abdominal aortic aneurysm to reduce future repairs.

  NIH research Vesteck, INC · Malvern, UNITED STATES · NIH-11414951

• Triglyceride-rich lipoproteins and abdominal aortic aneurysm growth

  A study exploring how fats in the blood (TRLs) influence the growth of abdominal aortic aneurysms to find non-surgical ways to protect against rupture, especially in people aged 65 and older.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11389655

• Using genetics to uncover how abdominal aortic aneurysms develop

  A research team will study how genetic differences influence abdominal aortic aneurysm to help with earlier prevention and better treatment.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11382092

• Phospholipid-based nanotherapies to treat abdominal aortic aneurysm

  A new nanoparticle treatment is being developed to slow or stop the growth of abdominal aortic aneurysms in adults.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11374518

• Vascular smooth muscle cell ferroptosis and abdominal aortic aneurysm

  A study to understand how a specific type of cell death in blood vessel walls may drive abdominal aortic aneurysm and if new targets could prevent rupture.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11373578

• PERK-blocking treatments to slow or stop abdominal aortic aneurysm progression

  Finding out whether medicines that block a cell stress pathway called PERK can protect the aorta in people with abdominal aortic aneurysm.

  NIH research University of Virginia · Charlottesville, United States · NIH-11348188

• PAR2 role in abdominal aortic aneurysm development

  Researchers are studying how a specific receptor (PAR2) in blood vessels might contribute to the development and progression of abdominal aortic aneurysms, with potential pathways to new treatments for people with the condition.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11332797

• Could vaping increase abdominal aortic aneurysm risk across generations

  This project looks at whether parents' vaping or nicotine exposure can cause biological changes that make their children more likely to develop abdominal aortic aneurysms.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11332766

• Deciding when to stop yearly CT scans after repair of an abdominal aortic aneurysm

  This project compares keeping yearly CT scans versus less frequent imaging to help Veterans who had endovascular aortic aneurysm repair avoid unnecessary risks.

  NIH research White River Junction VA Medical Center · White River Junction, UNITED STATES · NIH-11311794

• PCSK9 inhibitors and abdominal aortic aneurysm growth

  A new study asks whether lowering LDL cholesterol with PCSK9 inhibitors can slow the growth of abdominal aortic aneurysms in older adults.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11309600

• GCN2 and amino acid restriction in abdominal aortic aneurysm

  This project looks at how a cellular stress pathway called GCN2, activated by limiting amino acids, might help slow or prevent abdominal aortic aneurysm in people at risk.

  NIH research Northwestern University · Chicago, United States · NIH-11295475

• Targeted treatments to slow or prevent abdominal aortic aneurysm growth

  Looks at whether blocking a protein called BRD4 in artery muscle cells and delivering therapy directly to the aorta can slow or prevent abdominal aortic aneurysm in people at risk.

  NIH research University of Virginia · Charlottesville, United States · NIH-11295470

• What makes abdominal aortic aneurysms grow and weaken

  Researchers are looking at why the wall of the belly artery weakens and can burst in people with abdominal aortic aneurysms by studying cell survival and the artery's outer layer.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11289478

• Genes behind abdominal aortic aneurysm

  Researchers will use large-scale genetic and tissue data to find genes and biological signals that could help prevent or treat abdominal aortic aneurysms in people at risk.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11161577

• Investigating how amino acid starvation affects abdominal aortic aneurysms

  This study is looking at how cutting back on certain amino acids in your diet might help slow down the growth of abdominal aortic aneurysms in older adults, and it aims to find new, non-surgical ways to keep your aorta healthy.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-11122292

• Investigating a receptor's role in abdominal aortic aneurysms

  This study is looking at how a specific protein called PAR2 affects the growth and worsening of abdominal aortic aneurysms, with the goal of finding new treatment options for patients beyond just surgery.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11121653

• Targeting inflammation to prevent abdominal aortic aneurysm progression

  This study is looking at how inflammation in certain cells affects the growth of abdominal aortic aneurysms and is exploring a protein called BRD4 to find new ways to help prevent these aneurysms from getting worse, which could lead to better treatments for people at risk.

  NIH research University of Virginia · Charlottesville, United States · NIH-11115830

• Understanding a Protein's Role in Abdominal Aortic Aneurysms

  This research looks into a specific protein called BAF60c to better understand how abdominal aortic aneurysms develop, hoping to find new ways to treat them.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11112304

• How e-cigarettes may affect the risk of abdominal aortic aneurysms across generations

  This study is looking at how using e-cigarettes and being exposed to nicotine might lead to a serious condition called abdominal aortic aneurysms (AAAs), and it aims to understand how these factors could cause changes in genes that might affect not just the person using e-cigarettes, but also their children.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11105516

• Understanding Cell Death in Abdominal Aortic Aneurysms

  This research explores how a specific type of cell death in blood vessel walls might contribute to abdominal aortic aneurysms, hoping to find new ways to prevent or treat this serious condition.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11097177

• New Nanoparticle Treatment for Abdominal Aortic Aneurysm

  This research explores a new way to deliver anti-inflammatory medicine using tiny particles to help patients with abdominal aortic aneurysms.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11090423

• Finding non-surgical ways to manage abdominal aortic aneurysms

  This study is looking at a new way to treat abdominal aortic aneurysms without surgery by focusing on a protein called PERK, which could help slow down or even reverse the condition, making it safer for patients like you.

  NIH research University of Virginia · Charlottesville, United States · NIH-11072064

• Understanding how stress in cells contributes to the growth of abdominal aortic aneurysms

  This study is looking at how stress in cells might cause abdominal aortic aneurysms (AAAs) to grow, especially in veterans, by exploring how immune cells and blood vessel cells interact, so we can better understand what happens in this serious condition.

  NIH research Veterans Health Administration · Ann Arbor, United States · NIH-11048771

• Understanding how abdominal aortic aneurysms progress

  This study is looking into how inflammation and cell death in the aorta can make abdominal aortic aneurysms worse, with the goal of finding new ways to help manage or treat this serious condition for patients.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11046660

• Effects of a medication on the growth of abdominal aortic aneurysms

  This study is looking at whether a medication that lowers cholesterol can help prevent the growth of small abdominal aortic aneurysms in older adults, and it’s for people who have this condition and want to explore new treatment options.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11014326

• Investigating the role of a specific microRNA in abdominal aortic aneurysm

  This study is looking at how a tiny molecule called microRNA-146a affects the health of the abdominal aorta, especially for people at risk of abdominal aortic aneurysms, to see if it could help create new non-surgical treatments to keep their aorta strong and prevent serious problems.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11001154

• Investigating how a specific protein affects abdominal aortic aneurysms

  This study is looking at how a specific protein called TGFβ affects the growth of abdominal aortic aneurysms (AAAs) to help find new ways to treat this condition for people who have it.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-10995575

• Evaluating the need for ongoing imaging after aortic aneurysm repair in Veterans

  This study looks at how often veterans who have had surgery for a bulging blood vessel in the belly should get follow-up scans, especially considering the risks these scans might pose, like kidney problems, particularly for older patients with other health issues, to help figure out when these check-ups might not be ne

  NIH research White River Junction VA Medical Center · White River Junction, UNITED STATES · NIH-10923799

• Investigating how cell death affects abdominal aortic aneurysms

  This study is looking at how certain cells in your blood vessels might die in a way that contributes to the growth of abdominal aortic aneurysms, which can be a serious health issue, and it aims to find new ways to treat this condition, especially for those affected by smoking or genetics.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10879017

• Understanding how platelets and macrophages help heal abdominal aortic aneurysms

  This study is looking at how certain blood cells help heal abdominal aortic aneurysms, which can be dangerous for older adults, and aims to find new ways to improve healing and possibly avoid surgery.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-10869063

• Finding protein markers that indicate risk for abdominal aortic aneurysm

  This study is looking for certain proteins in the blood that might help predict if someone is at risk of developing an abdominal aortic aneurysm (AAA), which is a serious health issue, and it's designed for anyone interested in understanding more about their health risks.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10846849

• Investigating the role of BAF60c in abdominal aortic aneurysms

  This study is looking into how certain proteins affect the health of blood vessel cells and may lead to abdominal aortic aneurysms, with the goal of finding new ways to treat this serious condition.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10846748

• Understanding how thrombospondin-1 helps prevent abdominal aortic aneurysm rupture

  This study is looking at how a protein called thrombospondin-1 helps protect against the dangerous bursting of abdominal aortic aneurysms, which can be life-threatening, and it aims to find out how certain immune cells are involved in this process, with hopes of discovering new ways to prevent aneurysm ruptures in pati

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-10823253

• Investigating the role of specific immune cells in abdominal aortic aneurysm

  This study is looking at how certain immune cells in the body might play a role in the growth of abdominal aortic aneurysms (AAA), with the hope of finding new ways to treat this condition without surgery, which could help patients in the future.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10756121

• Investigating a protein's role in abdominal aortic aneurysm development

  This study is looking at how a protein called DOCK2 affects inflammation and the weakening of blood vessels that can lead to abdominal aortic aneurysms (AAA), with the hope of finding new treatments for this condition.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-10417112

Related topics

Quick answers

How many Abdominal Aortic Aneurysm clinical trials are recruiting right now?

22, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (9 trials), Italy (6 trials), Spain (4 trials), France (3 trials), Netherlands (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →