Using Magnetic Resonance Elastography to assess abdominal aortic aneurysms
Official title: Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
Run by Ohio State University · NCT02387255 · Data updated 2026-11-12
This study is testing if a new imaging technique can help doctors better understand the risk of rupture in abdominal aortic aneurysms by measuring how stiff they are.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 165 (estimated) |
| Sponsor | Ohio State University Academic / other |
| Locations | 1 site (Columbus, Ohio) |
| Status | Recruiting |
| Started | October 2014 |
| Main results expected | October 31, 2030 |
| Study ends | October 31, 2030 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT02387255 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with abdominal aortic aneurysms who can tolerate MRI procedures.
✕Probably not a fit
Patients who are claustrophobic, pregnant, or have non-MRI safe metal/devices in their body may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to utilize Magnetic Resonance Elastography (MRE) to measure the stiffness of abdominal aortic aneurysms (AAA), providing a more sensitive assessment of rupture risk compared to traditional diameter measurements. By validating stiffness estimates against mechanical testing and histopathology in AAA patients undergoing surgery, the study seeks to enhance the understanding of AAA risk factors. MRE is a non-invasive technique that could revolutionize the diagnosis and treatment of various diseases by making stiffness assessments widely available.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate risk assessments for AAA rupture, potentially improving patient outcomes.
How similar studies have gone: While MRE is already used for assessing hepatic fibrosis, its application in evaluating AAA stiffness is novel and has not been extensively tested in this context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must be able to lie flat on their back in the scanner for up to 60 minutes * Must be able to hold breath for up to 15 seconds Exclusion Criteria: * Patients who are claustrophobic * Patients who are pregnant * Patients with any unapproved, non-MRI save metal/devices in or on their body
Where it's running
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The Ohio State University Medical Center
Columbus, Ohio, United States Recruiting
Study contacts
- Principal investigator: Arunark Kolipaka, PhD — The Ohio State University Medical Center Dept. of Radiology
- Study coordinator: Kristin L Thompson, B.S.
- Email: Kristin.Thompson@osumc.edu
- Phone: 614-366-5429
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Cardiovascular Rehabilitation After Abdominal Aortic Aneurysm Repair
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Poland–Italy Aortic Bridge Registry: PERCUTEK Tycheseal for Abdominal Aortic Aneurysm
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We will test whether a new PET tracer ([64Cu]-RYM2) can safely image MMP activity in people with abdominal aortic aneurysm and in healthy volunteers.
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CTA registry for abdominal aortic aneurysm measurements
This registry will collect CT angiography scans from people with abdominal aortic aneurysms to see if CTA measurements reliably describe aneurysm size and features.
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Cygnum aneurysm sac lining used with EVAR for abdominal aortic aneurysm
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.