Improving pain control after abdominal aortic aneurysm surgery
Post-Operative Pain Control After Aortic EndoaneurYsmEctomy
This study tests which pain relief method works better for adults after surgery for abdominal aortic aneurysms: an epidural or a series of injections in the abdominal muscles.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Policlinico S. Donato Academic / other |
| Locations | 1 site (San Donato Milanese, Milan) |
| Trial ID | NCT06244732 on ClinicalTrials.gov |
What this trial studies
This study evaluates postoperative pain management in adult patients undergoing elective open abdominal aortic aneurysm repair. It compares two methods of analgesia: epidural analgesia and repeated rectus fascia blocks. The goal is to determine which method provides better pain control and reduces complications associated with postoperative pain. The study is conducted in a single center and involves randomizing patients to receive one of the two analgesic techniques.
Who should consider this trial
Good fit: Ideal candidates are adult patients over 18 years old who are scheduled for elective open surgical treatment of an abdominal aortic aneurysm.
Not a fit: Patients who are pregnant, have chronic pain, or have contraindications to the analgesic methods will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and faster recovery for patients undergoing abdominal aortic aneurysm surgery.
How similar studies have performed: Previous studies have shown that multimodal analgesia, including epidural analgesia, can improve postoperative pain management, suggesting this approach has potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
* adult patients (age \> 18 years)
* patients who have given their consent to participate in the study
* patients undergoing elective "open" surgical treatment of an abdominal aortic aneurysm with a midline xipho-pubic incision.
Exclusion Criteria:
* Pregnant women
* Patients being treated for chronic pain
* Known allergy to drugs included in analgesia protocols
* Contraindications to the use of one of the two methods provided:
* refusal by the patient
* infection at the puncture site
* coagulopathy:
1. PTT \> 40 s and/or INR \> 1.4
2. platelet count \< 50,000/µL
3. taking antiplatelet or anticoagulant drugs that have not been discontinued in good time, according to international guidelines
* Emergent intervention
* Lack of consent to participate in the study
Where this trial is running
San Donato Milanese, Milan
- I.R.C.C.S. Policlinico San Donato — San Donato Milanese, Milan, Italy (Recruiting)
Study contacts
- Study coordinator: Mattia Ricotti
- Email: mattia.ricotti@grupposandonato.it
- Phone: +390252774236
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.