Clinical trial Recruiting at 1 site Observational Ages 18 and up

Italian registry of open and semi-conversion surgery after EVAR

Official title: Italian Multicenter Prospective Database for Open Conversions and SemiConversions After Endovascular Aneurysm Repair

Run by Azienda Ospedaliero-Universitaria di Parma · NCT04299984 · Data updated 2026-11-12

This project collects information to see how open or semi-conversion surgery works for people who have late complications after endovascular abdominal aortic aneurysm repair (EVAR).

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorAzienda Ospedaliero-Universitaria di Parma
Academic / other
Locations1 site (Parma)
StatusRecruiting
StartedJanuary 1, 2022
Main results expectedDecember 31, 2031
Study endsDecember 31, 2032
Registry record updatedJune 4, 2025
Trial IDNCT04299984 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people who previously had EVAR and now need open or laparoscopic surgery for EVAR complications, whether or not the endograft is removed.

Probably not a fit

People whose complications can be managed with repeat endovascular procedures or who require only extra-anatomical bypass without direct aortic/graft surgery will not be included and are unlikely to benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter database collecting technical details and outcomes for patients who undergo late open conversion (partial or total graft explantation) or semi-conversion (open or laparoscopic repair with graft preservation) after EVAR. Participating vascular surgery centers enter procedural details, early postoperative results, and long-term follow-up data. The registry excludes purely endovascular reinterventions and extra-anatomical bypasses not involving direct aortic/graft surgery. The goal is to compare real-world early and long-term outcomes of the two surgical approaches to inform future practice.

Why it matters

Potential benefit: If successful, the database could clarify which surgical approach leads to better short- and long-term outcomes and help surgeons choose the right procedure for patients with failed EVAR.

How similar studies have gone: Several single-center series have reported outcomes after open conversion or semi-conversion, but prospective multicenter registries like this are relatively limited, so this effort builds on prior reports while expanding scale and generalizability.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* open or laparoscopic surgery for EVAR complications, with or without endograft explantation

Exclusion Criteria:

* endovascular reinterventions
* extra-anatomical bypass surgery (e.g. femoro-femoral crossover bypass) not associated with direct aorta/endograft surgery

Where it's running

  • Azienda Ospedaliero-Universitaria di Parma
    Parma, Italy
    Recruiting

Study contacts

  • Principal investigator: Paolo Perini, MD — Parma University Hospital
  • Study coordinator: Paolo Perini, MD
  • Email: p.perini@live.com
  • Phone: +390521702349

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.