Italian registry of open and semi-conversion surgery after EVAR
Official title: Italian Multicenter Prospective Database for Open Conversions and SemiConversions After Endovascular Aneurysm Repair
Run by Azienda Ospedaliero-Universitaria di Parma · NCT04299984 · Data updated 2026-11-12
This project collects information to see how open or semi-conversion surgery works for people who have late complications after endovascular abdominal aortic aneurysm repair (EVAR).
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Azienda Ospedaliero-Universitaria di Parma Academic / other |
| Locations | 1 site (Parma) |
| Status | Recruiting |
| Started | January 1, 2022 |
| Main results expected | December 31, 2031 |
| Study ends | December 31, 2032 |
| Registry record updated | June 4, 2025 |
| Trial ID | NCT04299984 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people who previously had EVAR and now need open or laparoscopic surgery for EVAR complications, whether or not the endograft is removed.
✕Probably not a fit
People whose complications can be managed with repeat endovascular procedures or who require only extra-anatomical bypass without direct aortic/graft surgery will not be included and are unlikely to benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, multicenter database collecting technical details and outcomes for patients who undergo late open conversion (partial or total graft explantation) or semi-conversion (open or laparoscopic repair with graft preservation) after EVAR. Participating vascular surgery centers enter procedural details, early postoperative results, and long-term follow-up data. The registry excludes purely endovascular reinterventions and extra-anatomical bypasses not involving direct aortic/graft surgery. The goal is to compare real-world early and long-term outcomes of the two surgical approaches to inform future practice.
Why it matters
Potential benefit: If successful, the database could clarify which surgical approach leads to better short- and long-term outcomes and help surgeons choose the right procedure for patients with failed EVAR.
How similar studies have gone: Several single-center series have reported outcomes after open conversion or semi-conversion, but prospective multicenter registries like this are relatively limited, so this effort builds on prior reports while expanding scale and generalizability.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * open or laparoscopic surgery for EVAR complications, with or without endograft explantation Exclusion Criteria: * endovascular reinterventions * extra-anatomical bypass surgery (e.g. femoro-femoral crossover bypass) not associated with direct aorta/endograft surgery
Where it's running
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Azienda Ospedaliero-Universitaria di Parma
Parma, Italy Recruiting
Study contacts
- Principal investigator: Paolo Perini, MD — Parma University Hospital
- Study coordinator: Paolo Perini, MD
- Email: p.perini@live.com
- Phone: +390521702349
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Cardiovascular Rehabilitation After Abdominal Aortic Aneurysm Repair
This study tests whether a structured cardiovascular rehabilitation program after abdominal aortic aneurysm repair leads to better fitness and quality of life than standard postoperative care.
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Imaging inflammation in abdominal aortic aneurysm using a PET tracer
Researchers are testing whether a new PET tracer, 64Cu-DOTA-ECL1i, can image inflammation in an abdominal aortic aneurysm.
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Poland–Italy Aortic Bridge Registry: PERCUTEK Tycheseal for Abdominal Aortic Aneurysm
This registry will see how well the PERCUTEK Tycheseal stent-graft works and how safe it is for adults having endovascular repair of abdominal aortic aneurysms.
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PET scan to image MMP activity in abdominal aortic aneurysm
We will test whether a new PET tracer ([64Cu]-RYM2) can safely image MMP activity in people with abdominal aortic aneurysm and in healthy volunteers.
-
CTA registry for abdominal aortic aneurysm measurements
This registry will collect CT angiography scans from people with abdominal aortic aneurysms to see if CTA measurements reliably describe aneurysm size and features.
-
Cygnum aneurysm sac lining used with EVAR for abdominal aortic aneurysm
This trial will test whether adding the Cygnum sac lining to standard EVAR is safe and helps prevent type II endoleaks in people with abdominal aortic aneurysms.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.