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Clinical trials and research at Institut National de la Santé Et de la Recherche Médicale, France

• 71Clinical trials
• 9Countries

Newest trials

All recruiting trials (71)

• Thiamine to reduce brain injury in adults with alcohol use disorder

  This trial tests whether thiamine can help protect the brain in adults with moderate to severe alcohol use disorder who drink daily.

  Recruiting Phase 2 Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT07844720

• Investigating microcirculation with non-invasive devices in adults with or at risk for CKD

  This study tests two non-invasive devices (HEMI and SPG-NINOX) to see how small blood vessels behave in adults with or at risk for chronic kidney disease, hypertension, or type 2 diabetes.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT07604922

• Virological Monitoring of Seasonal Respiratory Infections in France

  This project tests how often common respiratory viruses show up in patients seen by primary care doctors in metropolitan France during the fall and winter.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT07599449

• Finding early biological signs of ALS

  This project will test whether a molecular fingerprint in spinal fluid can detect ALS early in people with ALS gene mutations, in early ALS patients, and in matched controls.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Tours, France · NCT07213440

• Child cognitive and emotional resilience after the November 13 attacks and intergenerational effects of trauma

  This project tests whether parents' exposure to the November 13, 2015 attacks affects their children's thinking, emotions, brain function, and stress hormones using brain scans, psychological and cognitive tests, and saliva samples.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Caen · NCT07203443

• Cortical Excitability and DLPFC Structure in Healthy Adults Using TMS, EEG, and High-Field MRI

  This study tests how reproducible brain signals from transcranial magnetic stimulation relate to the anatomy of the left prefrontal cortex in healthy adults.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Marseille · NCT07071259

• Identification of Cellular Biomarkers in Rare Eye Diseases

  This study tests whether specific gene and protein markers in cells and tears can distinguish adults with rare corneal diseases from others and relate to their eye symptoms.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris and 1 other locations · NCT07063719

• rTMS to improve BCI control for upper‑limb rehabilitation after chronic stroke

  This tests whether repeated transcranial magnetic stimulation (rTMS) helps people with chronic stroke use a brain–computer interface (BCI) to improve movement in their affected arm.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06951035

• Collecting stool samples to study gut microbiota and nutrition

  This study is trying to see how different diets affect the gut bacteria in people to better understand their link to health issues like obesity and diabetes.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Bobigny · NCT06941090

• Functional ultrasound (fUS) for measuring brain connectivity in newborns

  This project tests whether a new bedside functional ultrasound (fUS) scan can measure brain connectivity in newborns at high risk of neurodevelopmental problems, including very preterm infants, babies with growth restriction, or those with oxygen injury at birth.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06940713

• Exploring dopamine disruptions in traumatic coma using advanced imaging techniques

  This study is trying to see if using a special brain scan can help understand how dopamine changes in people with traumatic coma after a serious brain injury and if those changes relate to their recovery of consciousness.

  Recruiting Phase 2 Institut National de la Santé Et de la Recherche Médicale, France · Toulouse · NCT06930261

• Multimodal heart and liver imaging in adults from the Constances cohort

  This project uses advanced heart and liver imaging to see if scans can reveal early signs of disease in adults from the Constances population cohort.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06906042

• Understanding the genetics of intellectual disabilities and autism spectrum disorders

  This study is trying to gather information from families to see how certain genetic changes are linked to intellectual disabilities and autism, with the hope of improving treatment and care for those affected.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT06871696

• Investigating heat stress and well-being in urban environments

  This study is testing how different factors in city life affect people's heat stress and well-being during hot weather in the Ile-de-France region.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06850025

• Chlordecone exposure and prostate cancer in Martinique

  This project will see if exposure to the pesticide chlordecone is linked to prostate cancer in men who live in Martinique.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Fort-de-France and 1 other locations · NCT06773806

• Long-term monitoring of adults with type I interferon autoantibodies or genetic interferon defects

  We will follow adults who have autoantibodies to type I interferons or genetic defects that impair interferon responses to see if they develop more infections or autoimmune problems and how antibody levels change over time.

  Recruiting at 9 sites Institut National de la Santé Et de la Recherche Médicale, France · Lille and 8 other locations · NCT06762002

• Prenatal maternal mental health and infant brain development in congenital heart defects

  See if prenatal maternal psychological distress is linked to neurodevelopment at age one in babies with prenatally diagnosed critical cyanotic congenital heart defects who need neonatal open-heart surgery.

  Recruiting at 5 sites Institut National de la Santé Et de la Recherche Médicale, France · Marseille and 4 other locations · NCT06711666

• Investigating brain activity in patients with PRRT2-related dyskinesia

  This study is trying to see how brain activity changes during episodes of abnormal movements in people with a PRRT2 mutation to better understand what happens in their brains.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06701851

• Understanding the genetic causes of language development disorders in children

  This study is trying to find out the genetic reasons behind language development disorders in children to help understand and treat them better.

  Recruiting at 3 sites Institut National de la Santé Et de la Recherche Médicale, France · Corbeil-Essonnes and 2 other locations · NCT06660108

• Neuromodulation for motor recovery after stroke

  This study is testing whether a new brain stimulation technique can help stroke patients recover their movement better than a placebo.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris and 1 other locations · NCT06599931

• Using whole genome sequencing to diagnose atypical diabetes

  This study is testing if using whole genome sequencing can help doctors better diagnose unusual types of diabetes in adults compared to the usual method.

  Recruiting at 22 sites Institut National de la Santé Et de la Recherche Médicale, France · Amiens and 25 other locations · NCT06570278

• Understanding how aging affects time perception and brain function

  This study is trying to see how aging affects the way we perceive time and how our brains work, by comparing younger and older adults during various tasks.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Caen · NCT06349213

• Long-term follow-up of the EGEA cohort on respiratory and cardiac health

  This study looks at how asthma might affect heart health over time by following a group of people and collecting different health information from them.

  Recruiting at 5 sites Institut National de la Santé Et de la Recherche Médicale, France · Grenoble and 4 other locations · NCT06334705

• Understanding X-linked Moesin Associated Immunodeficiency

  This study looks at how to better treat boys with X-linked Moesin Associated Immunodeficiency by collecting health information to understand their infections and the effects of their genetic mutations.

  Recruiting at 2 sites Institut National de la Santé Et de la Recherche Médicale, France · Bethesda, Maryland and 9 other locations · NCT06278337

• Identifying biomarkers for endometriosis using menstrual blood

  This study is trying to find markers in menstrual blood that can help diagnose and understand endometriosis in women aged 18-45, both those with the condition and those without.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06245512

• Examining the airway epithelium in children with post-infectious bronchiolitis obliterans

  This study is trying to see if there are differences in the nose lining of young children who get sick from certain viruses and later develop post-infectious bronchiolitis obliterans compared to those who don’t.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Marseille · NCT06140901

• Investigating genetic factors in severe infections

  This study is trying to find out if certain genes make some people more likely to get severe infections than others by looking at patients with rare and serious infections.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT06102070

• Risk markers of arterial aging in older adults — Paris Prospective III-2

  This follow-up will re-examine people who took part in the original Paris cohort to measure changes in arterial stiffness and baroreflex over about 12–16 years and see if those changes predict later heart and blood vessel disease.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06079424

• Long-term follow-up of premature infants treated for patent ductus arteriosus

  This study looks at how well paracetamol worked to treat a heart condition in premature babies and how it affects their development as they grow older.

  Recruiting at 8 sites Institut National de la Santé Et de la Recherche Médicale, France · Angers and 7 other locations · NCT06064825

• Characterizing Repetitive Behaviors in OCD and Tic Disorders

  This study is testing if special brain activity measurements can help tell the difference between compulsions in OCD and tics in Tourette syndrome to improve treatment options for people aged 15 to 65.

  Recruiting at 3 sites Institut National de la Santé Et de la Recherche Médicale, France · Créteil and 2 other locations · NCT06050369

• Observational study on interstitial lung diseases from infancy to elderly

  This study is collecting health information from people of all ages with interstitial lung diseases to see how these conditions affect them over time.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT06036719

• Observational study on Mucopolysaccharidosis diseases in France

  This study is trying to learn more about Mucopolysaccharidosis diseases by collecting information from patients in France to understand how these rare conditions affect their lives.

  Recruiting at 14 sites Institut National de la Santé Et de la Recherche Médicale, France · Angers and 22 other locations · NCT06036693

• Evaluating high doses of favipiravir in healthy volunteers

  This study is testing how well healthy volunteers can tolerate high doses of favipiravir over two weeks to learn more about its safety and how the body processes it.

  Recruiting Phase 1 Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06024421

• Examining brain development in young children after mild traumatic brain injury

  This study is trying to see how mild concussions affect the brains and behavior of young children aged 3 to 5 compared to kids with other types of injuries.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Rennes · NCT06024122

• Examining Natural Killer Cells in Severe Asthma Patients

  This study is testing how natural killer cells in the immune system affect people with severe asthma, especially during asthma attacks caused by viruses, by comparing them to healthy individuals.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Marseille · NCT06015256

• Cognitive and behavioral treatment for people with environmental intolerance

  This study is testing a new online therapy program to see if it can help people with environmental intolerance feel better and improve their quality of life.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Paris · NCT05973214

• Assessing the burden of rare skin diseases

  This study is trying to understand how nine rare skin diseases affect the daily lives of patients and their families, including their emotional, social, and financial challenges.

  Recruiting at 6 sites Institut National de la Santé Et de la Recherche Médicale, France · Bobigny and 14 other locations · NCT05954416

• National cohort for congenital eye defects

  This study looks at how congenital eye defects affect vision and development in newborns, children, and adults over ten years to help improve care for those with these conditions.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT05954403

• Observational study on Primary Ciliary Dyskinesia

  This study looks at people with Primary Ciliary Dyskinesia to see what factors might affect how severe their condition is and to help improve their care.

  Recruiting at 18 sites Institut National de la Santé Et de la Recherche Médicale, France · Besançon and 31 other locations · NCT05951478

• Observing metabolic profiles in patients with imprinting disorders

  This study looks at the metabolic health of people, both adults and children, with imprinting disorders to see if there are common patterns and how these conditions affect their overall health.

  Recruiting at 8 sites Institut National de la Santé Et de la Recherche Médicale, France · Angers and 19 other locations · NCT05945576

• Observational study on Alport Syndrome

  This study is looking at how Alport syndrome affects people over time and whether new treatments that worked in animals can help improve their health and quality of life.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT05927467

• Observational cohort for Adult Onset Still Disease and Systemic onset Juvenile Idiopathic Arthritis

  This study is collecting information from adults and children with Adult Onset Still Disease and Systemic onset Juvenile Idiopathic Arthritis to better understand their symptoms and how the diseases progress.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT05927454

• Cohort study on cystinosis in Europe

  This study looks at how cystinosis affects the lives of patients in Europe and how different treatments impact their health and well-being.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT05901077

• Understanding how interferon works for treating myeloproliferative neoplasms

  This study is trying to see how a treatment called pegylated interferon works for people with certain blood cancers to understand why some patients respond better than others.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Villejuif, Île-de-France Region · NCT05850273

• Investigation of Alzheimer's predictors in people with memory complaints

  This study is trying to see if people with memory problems and positive amyloid tests will develop Alzheimer's disease over the next few years.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT05806697

• Noninvasive detection of IDH mutations in gliomas using MRI

  This study is trying to see if a special MRI can help find IDH mutations in brain tumors called gliomas to better guide treatment for patients with these tumors.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris and 1 other locations · NCT05700071

• Understanding liver disease linked to alcohol and metabolic syndrome

  This study is trying to find out what causes liver cancer in people with alcohol-related liver disease and fatty liver disease by looking at their health, diet, and immune system over several years.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Nice · NCT05623150

• Exploring touch sensations to improve feedback in prosthetics

  This study is testing how touch sensations can be improved in prosthetics to help amputees feel better and interact more naturally with their devices.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Marseille and 1 other locations · NCT05548322

• MRI analysis of individuals with autism and their families

  This study is trying to see if brain scans can help us understand the genetic and clinical features of autism in people with the condition and their families.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Gif-sur-Yvette and 1 other locations · NCT05470088

• Metabolic and infectious diseases in La Réunion

  Researchers are testing how common metabolic and infectious diseases are in La Réunion and what factors like microbiota and genetics might influence them, by examining 2,000 adults over two years.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · La Réunion, Saint-Pierre · NCT05400824

• Exploring factors in muscle diseases caused by LMNA gene mutations

  This study is trying to understand how changes in the LMNA gene affect muscle and heart problems in patients, to help improve their treatment.

  Recruiting at 4 sites Institut National de la Santé Et de la Recherche Médicale, France · Bron, Auvergne-Rhône-Alpes and 7 other locations · NCT05394506

• Identifying genes in systemic autoinflammatory diseases

  This study is trying to find new genes linked to rare autoinflammatory diseases to help doctors diagnose and treat patients better.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT05364294

• Exploring neuroplasticity through proprioceptive rehabilitation with muscle vibrations

  This study is testing if using muscle vibrations can help improve brain recovery and movement in people who are healing from a stroke or brain injury.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT05277519

• Characterizing autoimmune lymphocytes in type 1 diabetes

  This study is trying to understand the immune cells involved in type 1 diabetes by collecting samples from people with type 1 diabetes, other types of diabetes, and healthy individuals.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Bobigny, Île-de-France Region and 16 other locations · NCT05139784

• Investigating the role of immune cells and gut bacteria in type 1 diabetes in children

  This study is trying to see how immune cells and gut bacteria are connected to type 1 diabetes in children who are newly diagnosed or at high risk.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Antony and 1 other locations · NCT05054361

• Cohort study on the natural history of Parkinson's disease in France

  This study is trying to understand how Parkinson's disease changes over time by collecting information and blood samples from patients in France to help find new ways to treat it.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT04888364

• Validation and implementation of advanced MRI protocols

  This study is testing new MRI techniques to see if they can improve brain imaging for both healthy people and patients.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Toulouse · NCT04866940

• Analyzing macrophages in ALS and related motor impairments

  This study is trying to see if looking at certain immune cells in people with ALS and related motor issues can help find new ways to treat the disease.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT04816227

• Examining how mental training affects motor learning

  This study tests if mental training can help people improve their movement speed and accuracy by using techniques like brain stimulation and measuring how their bodies respond.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Dijon · NCT04784832

• Evaluating health effects of modern radiotherapy in children

  This study is trying to see how modern radiation therapy affects the long-term health and quality of life of children under 22 who have received or will receive this treatment.

  Recruiting at 5 sites Institut National de la Santé Et de la Recherche Médicale, France · Leuven and 4 other locations · NCT04746729

• Exploring genetic factors in autism and related disorders

  This study is trying to find out how certain genes might be linked to autism and related disorders by looking closely at genetic variations in large groups of people.

  Recruiting at 2 sites Institut National de la Santé Et de la Recherche Médicale, France · Grenoble, Grenoble and 5 other locations · NCT04727489

• Creating biological models to study liver diseases and tumors

  This study is trying to create new models to better understand liver diseases and tumors so that we can find better treatments for people suffering from these conditions.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Strasbourg · NCT04690972

• Investigating brain activity in epilepsy patients using implanted electrodes

  This study is testing how brain activity in patients with hard-to-treat epilepsy can help us understand their seizures and how it affects their thinking and sleep.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT04653012

• Investigating factors that contribute to remission in anorexia nervosa

  This study looks at different factors that might help or hinder recovery from anorexia nervosa in women to better understand why some people relapse while others improve.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT04560517

• Monitoring heart rhythms in patients with Fabry disease

  This study is testing how heart rhythms change over three years in people with Fabry disease using a special heart monitor to see how it relates to their overall heart health.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Paris · NCT04440254

• Biomarkers for CNV and response to anti-VEGF in eye disease

  This study tests blood and eye fluid biomarkers to see if they predict how people with type 1 choroidal neovascularization respond to anti-VEGF therapy.

  Recruiting at 2 sites Institut National de la Santé Et de la Recherche Médicale, France · Paris and 1 other locations · NCT04439708

• Exploring time perception in schizophrenia and bipolar disorder using virtual reality

  This study is trying to see how people with schizophrenia and bipolar disorder experience time differently by using virtual reality games.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Strasbourg · NCT04432116

• Investigating immune-related intestinal diseases in adults

  This study looks at how certain immune-related gut diseases in adults affect the balance of cells in the intestines and liver to see if it can lead to serious complications.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Créteil and 3 other locations · NCT04280510

• Understanding brain resilience in Alzheimer's disease and its variants

  This study is trying to understand how some people with Alzheimer's disease, especially those with early symptoms, can stay resilient and cope better by looking at their brain scans and thinking abilities.

  Recruiting at 2 sites Institut National de la Santé Et de la Recherche Médicale, France · Orsay and 1 other locations · NCT04150198

• Understanding the role of the subthalamic nucleus in Parkinson's disease

  This study is testing how a part of the brain called the subthalamic nucleus affects movement in people with Parkinson's disease and whether stimulating it can help improve their motor symptoms.

  Recruiting at 2 sites Institut National de la Santé Et de la Recherche Médicale, France · Paris, PARIS and 1 other locations · NCT01682668

• Long-term effects of childhood solid tumors and their treatments in survivors

  This study looks at the long-term health and quality of life of childhood cancer survivors treated for solid tumors in France to see how their past treatments affect them now.

  Recruiting at 5 sites Institut National de la Santé Et de la Recherche Médicale, France · Amiens and 35 other locations · NCT01620372

Quick answers

How many clinical trials run by Institut National de la Santé Et de la Recherche Médicale, France are recruiting right now?

71, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in France (70 trials), Belgium (2 trials), Martinique (1 trial), Denmark (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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