Clinical trial Recruiting at 1 site Observational

Virological Monitoring of Seasonal Respiratory Infections in France

Official title: Virological Surveillance of Acute Respiratory Infection in Primary Health Care in Metropolitan France

Run by Institut National de la Santé Et de la Recherche Médicale, France · NCT07599449 · Data updated 2026-11-12

This project tests how often common respiratory viruses show up in patients seen by primary care doctors in metropolitan France during the fall and winter.

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Quick facts

Study typeObservational
SexAll
Enrollment25000 (estimated)
SponsorInstitut National de la Santé Et de la Recherche Médicale, France
Government
Locations1 site (Paris)
StatusRecruiting
StartedMay 14, 2026
Main results expectedMay 14, 2031
Study endsMay 14, 2031
Registry record updatedAugust 3, 2026
Trial IDNCT07599449 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Patients with an acute respiratory infection seen by a Sentinelles-participating GP or pediatrician during the defined weeks, who provide informed oral consent (or parental consent for minors).

Probably not a fit

Patients not covered by Sentinelles clinics or outside the enrollment weeks may not benefit from surveillance insights.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational effort collects samples from patients with acute respiratory infections seen by Sentinelles physicians to monitor circulating viruses such as influenza, SARS-CoV-2, RSV, rhinovirus, and metapneumovirus. Saliva or nasopharyngeal swabs are analyzed to track virus activity across seasons. The study integrates primary care and public health networks to inform surveillance and response strategies. Participation is limited to clinicians in the Sentinelles network and patients meeting ARI criteria during weeks 40 to 15 annually. Data collection occurs at specified French sites coordinated by INSA and Sorbonne Université in Paris.

Why it matters

Potential benefit: Results could improve understanding of how respiratory viruses spread in France and help public health authorities tailor prevention and response efforts.

How similar studies have gone: Prior respiratory virus surveillance programs have successfully tracked circulating pathogens and informed public health actions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* be seen by a general practitioner or pediatrician participating in the Sentinelles surveillance program;
* between week 40 (late September-early October) and week 15 (mid-April) of each year
* have an acute respiratory infection (ARI) as defined below: Sudden onset of fever (or feeling of fever) and respiratory symptoms
* have given oral consent to participate in this monitoring or, in the case of minors, oral consent given by the child's legal guardian(s) present at the consultation

Exclusion Criteria:

* a person who is subject to a court-ordered protective measure;
* a person who is under guardianship or conservatorship, unless accompanied by their legal guardian or unless the legal guardian objects to their participation;
* a person who is not in a condition to receive information or give consent.

Where it's running

  • IPLESP - UMR S 1136, N° BC 2908, Faculté de médecine Sorbonne Université, site Saint Antoine, 27 rue Chaligny
    Paris, France
    Recruiting

Study contacts

  • Principal investigator: Thierry BLANCHON, MD, PhD — Institut National de la Santé Et de la Recherche Médicale, France
  • Study coordinator: Thierry BLANCHON, MD, PhD
  • Email: thierry.blanchon@iplesp.upmc.fr
  • Phone: +33664846662

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.