Risk markers of arterial aging in older adults — Paris Prospective III-2

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project re-invites survivors and original participants from the Paris Prospective Study III for a second physical exam roughly 12–16 years after baseline to describe the dynamics of vascular aging and baroreflex sensitivity. Participants will undergo high-precision carotid echo-tracking and a new ultrafast radial artery echo to measure arterial aging parameters in large and medium-sized arteries. Blood samples may be collected and biobanked depending on funding. The study will link changes in these vascular measures to subsequent cardiovascular disease events in the well-characterized cohort of 10,157 adults who were 50–75 years old at baseline.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Being enrolled in PPS3 and having signed an informed consent for PPS3-2

Exclusion Criteria:

* Institutionalized participants
* Participants under guardianship
* Participants under judicial safeguard measure

Where it's running

• Centre d'Investigation Précliniques
  Paris, France Recruiting

Study contacts

• Principal investigator: Jean-Philippe Empana, MD, PhD — Institut National de la Santé Et de la Recherche Médicale, France
• Study coordinator: Jean-Philippe Empana, MD, PhD
• Email: jean-philippe.empana@inserm.fr
• Phone: 33153988020

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.