Characterizing Repetitive Behaviors in OCD and Tic Disorders
Official title: Actimetric and Electrophysiological Analyses of Repetitive Behaviors (Tics and Compulsions)
Run by Institut National de la Santé Et de la Recherche Médicale, France · NCT06050369 · Data updated 2026-11-12
This study is testing if special brain activity measurements can help tell the difference between compulsions in OCD and tics in Tourette syndrome to improve treatment options for people aged 15 to 65.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 65 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Institut National de la Santé Et de la Recherche Médicale, France Government |
| Locations | 3 sites (Créteil and 2 other locations) |
| Status | Recruiting |
| Started | December 28, 2023 |
| Main results expected | December 27, 2027 |
| Study ends | December 27, 2027 |
| Registry record updated | February 12, 2026 |
| Trial ID | NCT06050369 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 15 to 65 who have been diagnosed with OCD and/or GTS.
✕Probably not a fit
Patients with other psychiatric or neurological disorders, or those unable to provide informed consent, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to objectively distinguish between compulsions associated with obsessive-compulsive disorder (OCD) and tics related to Gilles de la Tourette syndrome (GTS) by identifying specific electrophysiological and accelerometric markers. Patients aged 15 to 65 with OCD and/or GTS will be recruited, and their brain activity will be recorded using high-density EEG in a laboratory setting and portable EEG at home while performing tasks. The goal is to enhance treatment selection by providing clear biomarkers for these repetitive behaviors.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and tailored treatments for patients with OCD and tic disorders.
How similar studies have gone: While the approach of using electrophysiological markers is promising, it is relatively novel and has not been extensively tested in this specific context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * To be more of 15 years old or less than 65 years old * To suffer from OCD and/or GTS (depressive, anxious and attention deficit hyperactivity disorder (ADHD) comorbidities are accepted) * To be registered to the french social security (or something equivalent) * To give written consent to participate to the research * To have contraception for women participants (or to not have any sexual activity) Exclusion Criteria: * Patients with any other psychiatric disorders than those mentioned in the inclusion criteria * Patients with any other neurological disorder than GTS * Patients who are not able to take decisions for themselves * Pregnant women * Patients not allowed to get MRI due to contraindication * Patients not speaking french
Where it's running
-
Hôpital Albert Chenevier
Créteil, France Recruiting -
Hôpital Henri Mondor
Créteil, France Recruiting -
Hôpital Pitié Salpêtrière
Paris, France Recruiting
Study contacts
- Principal investigator: Luc MALLET, MD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Luc MALLET, MD
- Email: luc.mallet@inserm.fr
- Phone: +33157274000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.