Investigating factors that contribute to remission in anorexia nervosa
Study of Remission Factors in Anorexia Nervosa of Adult Women (REMANO)
This study looks at different factors that might help or hinder recovery from anorexia nervosa in women to better understand why some people relapse while others improve.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 275 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | Institut National de la Santé Et de la Recherche Médicale, France Government |
| Locations | 1 site (Paris) |
| Trial ID | NCT04560517 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on understanding the complex mechanisms underlying anorexia nervosa (AN), a severe eating disorder primarily affecting women. It aims to explore various risk factors, including genetic, biological, neuro-psychological, and social influences, that contribute to the maintenance and chronicity of AN. By examining reward processing abnormalities and other factors, the study seeks to shed light on the high rates of relapse and variability in recovery among patients. Participants will be assessed based on specific eligibility criteria related to their condition and ability to consent.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with anorexia nervosa who meet specific inclusion criteria, including a BMI of less than 18.5 kg/m².
Not a fit: Patients who are pregnant, breastfeeding, or have serious unstabilized physical or psychiatric illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment strategies for patients with anorexia nervosa, potentially reducing relapse rates.
How similar studies have performed: While the study addresses a critical area of anorexia nervosa, similar studies have shown varying degrees of success in understanding the underlying mechanisms of this complex disorder.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * DMS 5 criteria for Anorexia Nervosa * BMI \< 18.5 kg/m² * Being able to consent * fluent in French * Being affiliated to a social security scheme or being the beneficiary of such a scheme. * Having signed the informed consent Exclusion Criteria: * Deprived of liberty subject (judicial or administrative decision) * Refusal to participate * Presenting an unstabilized serious physical illness or psychiatric disorder compromising the follow up according investigator evaluation * Contraindication for IRMf * Pregnant or breast-feeding women
Where this trial is running
Paris
- Centre Hospitalier St Anne — Paris, France (Recruiting)
Study contacts
- Study coordinator: Philibert Duriez, MD
- Email: p.duriez@ghu-paris.fr
- Phone: +33145658345
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.