Investigating factors that contribute to remission in anorexia nervosa
Official title: Study of Remission Factors in Anorexia Nervosa of Adult Women (REMANO)
Run by Institut National de la Santé Et de la Recherche Médicale, France · NCT04560517 · Data updated 2026-11-12
This study looks at different factors that might help or hinder recovery from anorexia nervosa in women to better understand why some people relapse while others improve.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Women only |
| Enrollment | 275 (estimated) |
| Sponsor | Institut National de la Santé Et de la Recherche Médicale, France Government |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | April 6, 2021 |
| Main results expected | October 2026 |
| Study ends | October 2026 |
| Registry record updated | September 18, 2025 |
| Trial ID | NCT04560517 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with anorexia nervosa who meet specific inclusion criteria, including a BMI of less than 18.5 kg/m².
✕Probably not a fit
Patients who are pregnant, breastfeeding, or have serious unstabilized physical or psychiatric illnesses may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on understanding the complex mechanisms underlying anorexia nervosa (AN), a severe eating disorder primarily affecting women. It aims to explore various risk factors, including genetic, biological, neuro-psychological, and social influences, that contribute to the maintenance and chronicity of AN. By examining reward processing abnormalities and other factors, the study seeks to shed light on the high rates of relapse and variability in recovery among patients. Participants will be assessed based on specific eligibility criteria related to their condition and ability to consent.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment strategies for patients with anorexia nervosa, potentially reducing relapse rates.
How similar studies have gone: While the study addresses a critical area of anorexia nervosa, similar studies have shown varying degrees of success in understanding the underlying mechanisms of this complex disorder.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * DMS 5 criteria for Anorexia Nervosa * BMI \< 18.5 kg/m² * Being able to consent * fluent in French * Being affiliated to a social security scheme or being the beneficiary of such a scheme. * Having signed the informed consent Exclusion Criteria: * Deprived of liberty subject (judicial or administrative decision) * Refusal to participate * Presenting an unstabilized serious physical illness or psychiatric disorder compromising the follow up according investigator evaluation * Contraindication for IRMf * Pregnant or breast-feeding women
Where it's running
-
Centre Hospitalier St Anne
Paris, France Recruiting
Study contacts
- Study coordinator: Philibert Duriez, MD
- Email: p.duriez@ghu-paris.fr
- Phone: +33145658345
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Specialist Supportive Clinical Management for teens with anorexia or atypical anorexia
This study tests a teen-focused SSCM approach to help 13-17 year-olds with anorexia nervosa or atypical anorexia nervosa when other treatments haven’t worked or can’t be used.
-
Identifying Signatures of Gut Interoception in Functional Dyspepsia and Anorexia Nervosa
This study tests how the gut-brain connection works in people with functional dyspepsia or anorexia nervosa using brain imaging.
-
Online FBT-DBT for Caregivers of Teens with Anorexia Nervosa
This online program tests a combination of family-based and DBT skills to help caregivers of teens with anorexia nervosa manage stress and improve family support.
-
Eating Disorder Dynamic Intervention
A digital program is tested to help adults with eating disorders by sending real-time, personalized coping tips based on smartphone surveys and sensor data.
-
Hormone and metabolic patterns in hypothalamus-like brain cells from people with anorexia nervosa
This study will test whether hypothalamic-like neurons made from adult women with long-standing anorexia nervosa respond differently to metabolic hormones than neurons from healthy women.
-
Narrative medicine workshops to support teens and young adults with anorexia nervosa (virtual)
This program tests whether a six-week series of narrative medicine workshops can help 16–25-year-olds with anorexia nervosa express themselves, reflect, and build resilience.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.