Identifying genes in systemic autoinflammatory diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project focuses on systemic autoinflammatory diseases (SAIDs), which are rare and genetically diverse conditions characterized by intermittent febrile crises and inflammation. The study aims to identify novel genes and specific molecular signatures in patients with SAIDs, particularly those with unknown causes. By advancing the understanding of the pathophysiology of SAIDs, the researchers hope to facilitate faster diagnoses and personalized treatment strategies based on the identified genetic variations. The study will involve observational assessments of patients presenting with specific inflammatory symptoms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A patient presenting with a clinical and biological aseptic inflammatory syndrome associating one or more of the following signs: spontaneously resolving fever, abdominal (pain, diarrhea), locomotor (arthralgia, myalgia), thoracic (pain, pericarditis), cutaneous, sensory (uveitis, deafness), or renal (amyloidosis) involvement.

Exclusion Criteria:

* Adult subject to legal protection measures (guardianship, curatorship, safeguard of justice).

Where it's running

• Trousseau Hospital
  Paris, France Recruiting

Study contacts

• Study coordinator: Irina GIURGEA
• Email: irina.giurgea@inserm.fr
• Phone: +33144735295

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.