Cognitive and behavioral treatment for people with environmental intolerance
Official title: Effectiveness of a Cognitive and Behavioral Treatment Program in People With Idiopathic Environmental Intolerance (IEI)
Run by Institut National de la Santé Et de la Recherche Médicale, France · NCT05973214 · Data updated 2026-11-12
This study is testing a new online therapy program to see if it can help people with environmental intolerance feel better and improve their quality of life.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 82 (estimated) |
| Sponsor | Institut National de la Santé Et de la Recherche Médicale, France Government |
| Locations | 1 site (Paris, Paris) |
| Status | Recruiting |
| Started | February 20, 2024 |
| Main results expected | February 2027 |
| Study ends | November 2028 |
| Registry record updated | August 13, 2025 |
| Trial ID | NCT05973214 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been diagnosed with Idiopathic Environmental Intolerance and experience significant symptoms.
✕Probably not a fit
Patients with severe mental health disorders, such as severe depression or substance use disorder, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of a newly developed cognitive behavioral therapy (CBT) program for individuals suffering from Idiopathic Environmental Intolerance (IEI). The study employs a randomized controlled design, comparing outcomes between participants receiving the 8-week online CBT intervention and a wait-list control group. The program aims to address cognitive biases and negative expectations that may exacerbate symptoms attributed to environmental factors. The research seeks to enhance the quality of life for patients with IEI and contribute to the understanding of this complex condition.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the quality of life for patients suffering from Idiopathic Environmental Intolerance.
How similar studies have gone: While cognitive behavioral therapy has been effective in treating various psychological conditions, this specific application for Idiopathic Environmental Intolerance is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged ≥18 years, * Present a diagnosis of idiopathic environmental intolerance confirmed by the lead physician at the admission * Be affiliated to a social security regime. * Informed Consent Exclusion Criteria: * Severe depression, delusion disorder or substance use disorder * No access to internet * Non-French speakers * Currently participating to another research on IEI * Under an exclusion period for another study * Benefiting from French state aid known as AME * Deprivation of liberty by court or administrative order * Hospitalized without consent * Under protective measures * Pregnancy and/or breastfeeding
Where it's running
-
Unité de pathologies professionnelles et environnementales, Hôtel-Dieu
Paris, Paris, France Recruiting
Study contacts
- Principal investigator: Cedric Lemogne, PR, MD — Institut de Psychiatrie et des Neurosciences de Paris
- Study coordinator: Victor Pitron, MD, PHD
- Email: victor.pitron@aphp.fr
- Phone: 0142348608
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.